Rare Blood Cancers in 2021: Importance of Continued Exchange of Ideas [0.03%]
2021年罕见血液肿瘤的重要议题——持续交流思想的重要性
Naveen Pemmaraju
Naveen Pemmaraju
Siba El Hussein,Sa A Wang,Naveen Pemmaraju et al.
Siba El Hussein et al.
Our understanding of chronic myelomonocytic leukemia (CMML) has evolved tremendously over the past decade. Large-scale sequencing studies have led to increased insight into the genomic landscape of CMML and clinical implications of these ch...
First-Line PARP Inhibitors-Emerging Side Effects Require Caution: A Case of PARPi-Induced Pneumonitis [0.03%]
一线PARP抑制剂-新的不良反应要求更谨慎：一例PARP抑制剂所致肺炎中毒副作用的病例报告
Alistair McLaren,Douglas Cartwright,Ewen Ross et al.
Alistair McLaren et al.
Niraparib, an inhibitor of poly(adenosine diphosphate [ADP]-ribose) 1 and 2, has been shown to improve progression free survival in patients when used as maintenance treatment after first-line platinum-based chemotherapy in advanced stage (...
Novel Therapies in Myeloproliferative Neoplasms: Beyond JAK Inhibitor Monotherapy [0.03%]
我的增生性肿瘤的新疗法：JAK抑制剂单药治疗之外的方法
Sophia S Lee,Srdan Verstovsek,Naveen Pemmaraju
Sophia S Lee
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic disorders that consist classically of polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF). Janus kinase (JAK) inhibitors have become the standard of the...
Eli M Soyfer,Angela G Fleischman
Eli M Soyfer
Myeloid malignancies, stemming from a somatically mutated hematopoietic clone, can cause a wide variety of clinical consequences, including pancytopenia in myelodysplastic syndrome, overproduction of three myeloid lineages in myeloprolifera...
Jacob J Adashek,Joud Hajjar,Roy F Chemaly et al.
Jacob J Adashek et al.
The Impact of COVID-19 on Cancer Clinical Trials Conducted by NCI-Designated Comprehensive Cancer Centers [0.03%]
COVID-19对美国国家癌症研究所综合癌症中心资助的临床试验的影响
Diviya Gupta,Shumei Kato,Razelle Kurzrock
Diviya Gupta
Shumei Kato,Razelle Kurzrock
Shumei Kato
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a pandemic with major implications across the world. One of the most frequent causes of death from SARS-CoV-2 is fatal pneumonia from coronavirus disease 2019 (COVID-19), which...