Ranking the risk factors for Alzheimer's disease; findings from the UK Biobank study [0.03%]
来自英国生物样本库研究的阿尔茨海默病风险因素排名
Michael Allwright,Hamish D Mundell,Andrew N McCorkindale et al.
Michael Allwright et al.
Background: The cause of the most common form of dementia, sporadic Alzheimer's disease (AD), remains unknown. This may reflect insufficiently powered studies to date for this multi-factorial disorder. The UK Biobank data...
Dário Trindade,Maria Cachide,Tânia Soares Martins et al.
Dário Trindade et al.
Objective: Clusterin is involved in a variety of physiological processes, including proteostasis. Several clusterin polymorphisms were associated with an increased risk of developing Alzheimer's disease, the world-leading...
The 5XFAD mouse model of Alzheimer's disease displays age-dependent deficits in habituation to a novel environment [0.03%]
五倍阿尔茨海默病小鼠模型显示对新环境习惯化的年龄依赖性缺陷
Sabrina Smith,Sarah C Hopp
Sabrina Smith
Habituation is a form of learning characterized by a decrement in responsiveness to a stimulus that is repeated or prolonged. In rodents, habituation to a novel environment is characterized by a decrease in locomotion over time spent in a n...
Sadashiva K Pai
Sadashiva K Pai
Longitudinal grip strength is associated with susceptibility to the Sound Induced Flash Illusion in older adults [0.03%]
纵向握力与老年人对声音诱导闪光错觉的易感性有关
A O&#x; Dowd,R J Hirst,A Setti et al.
A O&#x; Dowd et al.
The precision of temporal multisensory integration is associated with specific aspects of physical functioning in ageing, including gait speed and incidents of falling. However, it is unknown if such an association exists between multisenso...
Longitudinal association between ß-amyloid accumulation and cognitive decline in cognitively healthy older adults: A systematic review [0.03%]
无β淀粉样蛋白积累与认知健康的老年人的认知下降的纵向关联：系统评价
Camille Parent,Louis-Simon Rousseau,David Predovan et al.
Camille Parent et al.
This systematic review examined the longitudinal association between amyloid-β (Aβ) accumulation and cognitive decline in cognitively healthy adults. It was conducted using the PubMed, Embase, PsycInfo, and Web of Science databases. The m...
Multimodal imaging of the aging brain: Baseline findings of the LoCARPoN study [0.03%]
多模态脑影像学在老年痴呆症研究中的应用：LoCARPoN 研究的基线结果
Pallavi Nair,Kameshwar Prasad,Parthiban Balasundaram et al.
Pallavi Nair et al.
We quantified and investigated multimodal brain MRI measures in the LoCARPoN Study due to lack of normative data among Indians. A total of 401 participants (aged 50-88 years) without stroke or dementia completed MRI investigation. We assess...
Sadashiva K Pai
Sadashiva K Pai
Muscular and cortical activation during dynamic and static balance in the elderly: A scoping review [0.03%]
老年人静态和动态平衡期间的肌肉和皮质激活：综述型研究
Maria Rubega,Roberto Di Marco,Marianna Zampini et al.
Maria Rubega et al.
Falls due to balance impairment are a major cause of injury and disability in the elderly. The study of neurophysiological correlates during static and dynamic balance tasks is an emerging area of research that could lead to novel rehabilit...
Association of positive and negative life events with cognitive performance and psychological status in late life: A cross-sectional study in Northern Portugal [0.03%]
葡萄牙北部老年人生活积极和消极事件与认知功能和心理状态的关联：一项横断面研究
T C Castanho,N C Santos,C Meleiro-Neves et al.
T C Castanho et al.
Objectives: Life events have important effects on psychological well-being. Yet, studies have mainly focused on exploring the impact of traumatic and negative experiences on health and well-being, with positive events rec...