Mohammadamin Parsaei,Hossein Sanjari Moghaddam,Mohammad Hadi Aarabi
Mohammadamin Parsaei
Neural distinctiveness and discriminability underlying unitization and associative memory in aging [0.03%]
老化过程中单元化和联想记忆下的神经独特性与判别性
A C Steinkrauss,C M Carpenter,M K Tarkenton et al.
A C Steinkrauss et al.
Previous work has suggested unitized pairs behave as a single unit and more critically, are processed neurally different than those of associative memories. The current works examines the neural differences between unitization and non-uniti...
Fergus I M Craik
Fergus I M Craik
In this article I reprise some selected findings and issues from my previous behavioural work on age-related differences in memory, and relate them to current work on the neural correlates of encoding, retrieval and representation. In parti...
Rethinking the detection and diagnosis of Alzheimer's disease: Outcomes of a European Brain Council project [0.03%]
阿尔茨海默病的检测与诊断的新思维：欧洲大脑理事会项目成果
Annette Dumas,Frédéric Destrebecq,Giovanni Esposito et al.
Annette Dumas et al.
Alzheimer's disease (AD), the most common form of dementia, is a progressive and debilitating neurodegenerative condition which robs people of their memory, their independence, their relationships and, ultimately, their lives. It affects cl...
Cerebrovascular integrity affects gradients of aging-related dopamine D1 differences in the striatum [0.03%]
脑血管完整性影响纹状体内多巴胺D1受体衰老梯度变化
Jarkko Johansson,Nina Karalija,Alireza Salami
Jarkko Johansson
Extant research suggest aging-related losses of different dopaminergic markers, including presynaptic dopamine transporters as well as post-synaptic DA receptors. Given the central role of DA in neurocognitive functions, maintenance of a he...
Janice X Li,Hannah L Nguyen,Tianchen Qian et al.
Janice X Li et al.
Hippocampal sclerosis of aging (HS-A) is a common degenerative neuropathology in older individuals and is associated with dementia. HS-A is characterized by disproportionate hippocampal atrophy at autopsy but cannot be diagnosed during life...
Sleep deprivation aggravated amyloid β oligomers-induced damage to the cerebellum of rats: Evidence from magnetic resonance imaging [0.03%]
睡眠剥夺加重淀粉样蛋白β低聚物诱导的大鼠小脑损伤：磁共振成像证据
Wensheng Guo,Xin Mao,Ding Han et al.
Wensheng Guo et al.
For quite a long time, researches on Alzheimer's disease (AD) primarily focused on the cortex and hippocampus, while the cerebellum has been ignored because of its abnormalities considered to appear in the late stage of AD. In recent years,...
In the quest for the ideal sweetener: Aspartame exacerbates selected biomarkers in the fruit fly (Drosophila melanogaster) model of Alzheimer's disease more than sucrose [0.03%]
在寻找理想甜味剂的道路上：天冬氨酰苯丙氨酸甲酯会加重果蝇（Drosophila melanogaster）阿尔茨海默病模型中某些生物标志物，而蔗糖则不会
Bukola Christiana Adedayo,Stephanie Tolulope Akinniyi,Opeyemi Babatunde Ogunsuyi et al.
Bukola Christiana Adedayo et al.
This study evaluated the effect of dietary inclusions of aspartame and sucrose on some selected behavioral and biochemical indices linked with Alzheimer's disease in a transgenic fruit fly (Drosophila melanogaster) model expressing human am...
Reduction of brain stem pathology and transient amelioration of early cognitive symptoms in transgenic mice treated with a monoclonal antibody against α-synuclein oligomers/protofibrils [0.03%]
针对α-突触核蛋白低聚物/原纤维的单克隆抗体可降低小鼠脑干病理并暂时改善其早期认知症状
S Ekmark-Lewén,A Aniszewska,A Molisak et al.
S Ekmark-Lewén et al.
Immunotherapy against alpha-synuclein (α-syn) is a promising novel treatment strategy for Parkinson's disease (PD) and related α-synucleinopathies. We have previously shown that systemic treatment with the monoclonal oligomer/protofibril-...
Sadashiva Pai
Sadashiva Pai