Larger dlPFC and vmPFC grey matter volumes are associated with high adherence to the Mediterranean diet: A cross-sectional study in older adults [0.03%]
较大的dlPFC和vmPFC灰质体积与老年人地中海饮食依從性高有关：一项横断面研究
Belina Rodrigues,Carlos Portugal-Nunes,Ricardo Magalhães et al.
Belina Rodrigues et al.
Dietary self-control is associated with inter-individual differences in neuroanatomy. Yet, whether such inter-individual differences are also associated with healthier dietary patterns is yet to be determined. In this cross-sectional study,...
The prevalence of sleep loss and sleep disorders in young and old adults [0.03%]
年轻人和老年人失眠及睡眠障碍的流行性研究
Vibha Madan Jha
Vibha Madan Jha
The ability to sleep declines with age. The National Sleep Foundation, USA has recommended a minimum sleep amount for all ages. Individuals who experience sleep lesser than the recommended amount could be sleep-deprived. Several factors lik...
Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer's disease pathology in mouse models of Alzheimer's disease [0.03%]
阿尔茨海默病小鼠模型中的年龄相关脑ACE-2降低并非由阿尔茨海默病病理恶化所致
Robert MacLachlan,Charles E Evans,Siew Yeen Chai et al.
Robert MacLachlan et al.
An imbalance in the circulatory and organ-specific renin-angiotensin system (RAS) pathways is associated with age-related dysfunction and disease including cardiovascular burden and more recently Alzheimer's disease (AD). It is currently un...
Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy [0.03%]
3xTg-AD小鼠星形胶质细胞转录组分析：衰老、疾病进展和抗Aβ免疫治疗的影响
Doris Lambracht-Washington,Min Fu,Navid Manouchehri et al.
Doris Lambracht-Washington et al.
Background: To investigate how changes in expression of glial genes relate to a progression of Alzheimer's disease (AD) pathology, and how anti-Aβ immunotherapy impact these changes, we conducted a transcriptomic analysi...
Rostral anterior cingulate connectivity in older adults with subthreshold depressive symptoms: A preliminary study [0.03%]
前扣带回脑网络在轻度抑郁老年人中的作用的初步研究
Andrew M Gradone,Gabriell Champion,Keith M McGregor et al.
Andrew M Gradone et al.
Subthreshold depressive symptoms are highly prevalent among older adults and are associated with numerous health risks including cognitive decline and decreased physical health. One brain region central to neuroanatomical models of depressi...
To sleep or not to sleep - Effects on memory in normal aging and disease [0.03%]
sleeping还是not sleeping：正常衰老和疾病状态下的记忆效应
Daniel Kroeger,Ramalingam Vetrivelan
Daniel Kroeger
Sleep behavior undergoes significant changes across the lifespan, and aging is associated with marked alterations in sleep amounts and quality. The primary sleep changes in healthy older adults include a shift in sleep timing, reduced slow-...
Josef Zihl,Simone Reppermund
Josef Zihl
Cognitive decline as part of mental ageing is typically assessed with standardized tests; below-average performance in such tests is used as an indicator for pathological cognitive aging. In addition, morphological and functional changes in...
Compensatory cognition in neurological diseases and aging: A review of animal and human studies [0.03%]
神经性疾病和衰老中的代偿性认知：动物及人类研究综述
Kanishka,Sushil K Jha
Kanishka
Specialized individual circuits in the brain are recruited for specific functions. Interestingly, multiple neural circuitries continuously compete with each other to acquire the specialized function. However, the dominant among them compete...
Longitudinal trajectories of spectral power during sleep in middle-aged and older adults [0.03%]
中老年人睡眠期间功率谱的纵向变化轨迹
Chenlu Gao,Michael K Scullin
Chenlu Gao
Age-related changes in sleep appear to contribute to cognitive aging and dementia. However, most of the current understanding of sleep across the lifespan is based on cross-sectional evidence. Using data from the Sleep Heart Health Study, w...
Narges Ahangari,Corinne E Fischer,Tom A Schweizer et al.
Narges Ahangari et al.
Cognitive resilience in Alzheimer's disease (AD) can be defined as retention of high cognition despite presence of considerable cerebral AD lesions. We sought to identify factors associated with this phenomenon. Data were obtained from Nati...