Francesco Pipitone,Caterina Bernetti,Gianfranco Di Gennaro et al.
Francesco Pipitone et al.
•TMT is a viable biomarker for sarcopenia in dementia imaging.•Craniofacial muscle loss correlates with cognitive impairment.•Muscle fat infiltration links to brain atrophy in AD and DLB.•Sarcopenia and dementia share metabolic and infl...
Age-related differences in asymmetric synapses across the central inferior colliculus in the Fischer Brown Norway rat [0.03%]
在Fischer棕色挪威大鼠中央下丘中与年龄相关的不对称突触差异
Gillian L Barach,Alexa Wawrzyniak,Justine Busby et al.
Gillian L Barach et al.
The rapidly aging populations of industrial countries are commonly affected by age-related hearing loss (ARHL). A broad mechanistic theme to ARHL are imbalances to excitation and inhibition in the central auditory system in response to the ...
Plasma neurofilament light is associated with hippocampal volume and memory performance but not functional connectivity in older adults with and without mild cognitive decline [0.03%]
血浆神经丝轻链与老年伴或不伴有轻度认知障碍成年人的海马体积和记忆力相关，但与其功能连接无关
Youjin Jung,Scott E Counts,Benjamin M Hampstead et al.
Youjin Jung et al.
Plasma neurofilament light chains (pNfL) have shown promise as a biomarker for tracking and predicting neurodegeneration, such as cortical atrophy and hypometabolism, in Alzheimer's Disease (AD). However, it is still not clear whether neuro...
Increased functional integration of emotional control network across the adult lifespan [0.03%]
情绪控制网络的功能整合随着成人年龄的增长而提高
Leona Rahel Bätz,Shuer Ye,Melissa Schubbert et al.
Leona Rahel Bätz et al.
Emotional well-being has often been shown to improve across the adult lifespan. The corresponding effects, however, in the emotion regulation brain networks remain underexplored. By utilizing large-scale datasets such as the Human Connectom...
Associations between subjective cognitive concern, brain network connectivity, and cognitive performance in cognitively normal older adults [0.03%]
认知正常的老年人主观认知顾虑与大脑网络连接和认知表现之间的关联
Kimberly Albert,Brian Boyd,Brenna McDonald et al.
Kimberly Albert et al.
Subjective Cognitive Decline (SCD) is the perception of a persistent decline in cognitive function and self-reported concerns over cognitive ability in older adults with normal objective cognitive performance. SCD is associated with increas...
Evaluation of candidate RT-qPCR reference genes in the aging African turquoise killifish brain [0.03%]
评估非洲土耳其鱼脑衰老过程中候选RT-qPCR参考基因的表现
Emily Whisenant,Arne C Lekven
Emily Whisenant
Reference genes (RGs) are typically used to normalize gene expression from RT-qPCR experiments. However, the expression of commonly used RGs can vary across different physiological conditions, such as aging, and potentially lead to inaccura...
The association of late-life depressive symptoms with brain amyloid-β deposition: the ARIC-PET study [0.03%]
基于ARIC-PET研究的晚年抑郁症状与脑淀粉样β沉积的关系
Sylee Kanetkar,Valerie N Morrill,Marco T Egle et al.
Sylee Kanetkar et al.
Late-life depression is associated with an increased risk of developing dementia related to Alzheimer's disease, yet the mechanism underlying this relationship remains poorly understood. This study investigated the association of late-life ...
Influence of aging and task-related activation on descending cortical modulation of spinal sensorimotor circuitry [0.03%]
老化及任务相关的激活对下行皮质调控脊髓感觉运动环路的影响
Alejandro J Lopez,Terrence J Glover,Taylor M Leone et al.
Alejandro J Lopez et al.
The objective of this study was to evaluate the effects of aging on descending modulation of spinal reflexes across different task conditions. In healthy young (YA; age 27 ± 4 years) and older (OA; age 63 ± 10 years) adults, we utilized p...
Advanced brain aging mediates the relationship between cardiovascular health and aphasia severity in chronic stroke [0.03%]
高级脑老化介导了心血管健康与慢性卒中患者失语症严重程度之间的关系
Natalie Busby,Ida Rangus,Nicholas Riccardi et al.
Natalie Busby et al.
Introduction: There is evidence that overall physical health in general and cardiovascular risk (CV) factors in particular are associated with structural brain changes and recovery trajectories in stroke aphasia, however ...
Contributions of lifestyle, education, and cardiovascular risk factors to the brain age gap [0.03%]
生活方式、教育和心血管危险因素对脑年龄差距的影响
Kostas Stoitsas,Pieter Bakx,Trudy Voortman et al.
Kostas Stoitsas et al.
The brain age gap is the difference between chronological age and the age predicted from Magnetic Resonance Imaging (MRI) brain scans. We investigated the influence of life habits and cardio-metabolic factors on this gap. A convolutional ne...