Ioannis-Eleemon Papagiannopoulos-Vatopaidinos,Maria I Papagiannopoulou,Eleni N Dotsika
Ioannis-Eleemon Papagiannopoulos-Vatopaidinos
Background: Dry fasting (DF) presents three primary risks: hypovolemia, hypertonicity, and hypoglycemia. The first two have been shown to be effectively compensated, and the respective mechanisms have been studied. The be...
PCSK9-promoted LDLR degradation: Recruitment or prevention of essential cofactors? [0.03%]
PCSK9促进LDLR降解:募集或阻止必要的辅因子?
Rong Li,Cindy Xinyi Zhang,Junli Liu et al.
Rong Li et al.
Assessment of DNA glycation in the prediabetic State: Early indicator of glycemic stress [0.03%]
糖尿病前期DNA糖基化的评估:早期的血糖压力指标
Tanish Baweja,Abhishek Dikshit,Shazia Bano et al.
Tanish Baweja et al.
Introduction: Glycation of nucleic acids secondary to hyperglycemia can lead to structural alterations and the formation of neoantigens. These molecular changes may elicit an early immune response. This study investigates...
Recovery time of diabetic ketoacidosis in Africa: Systematic review and meta-analysis [0.03%]
非洲糖尿病酮症酸中毒的恢复时间:系统评价和荟萃分析
Tadios Lidetu,Simon Birhanu,Addisu Simachew Asgai et al.
Tadios Lidetu et al.
Background: Diabetes mellitus is a long-term metabolic disease marked by consistently elevated blood glucose levels. Diabetic ketoacidosis is the medical consequence of diabetes mellitus that has the highest attributed fa...
Higher serum uric acid levels and risk of all-cause mortality in general population: a systematic review and meta-analysis [0.03%]
血尿酸水平与总死亡率的关系:系统评价和Meta分析
Md Golam Rabbani,Sheikh M Alif,Cammie Tran et al.
Md Golam Rabbani et al.
Background: Population-based studies have reported a relationship between high serum uric acid (SUA) levels and all-cause mortality; however, findings are inconsistent. To address this issue, we conducted a meta-analysis ...
Sleep quality and well-being in obesity-hypoventilation syndrome versus obstructive sleep apnea with obesity: A comparative study [0.03%]
肥胖型低通气综合征与肥胖型阻塞性睡眠呼吸暂停的睡眠质量和幸福感比较研究
Vasiliki Epameinondas Georgakopoulou,Athina Lazaridou,Athanasios Voulgaris et al.
Vasiliki Epameinondas Georgakopoulou et al.
Background: Only a few studies in the published literature have assessed the well-being, and the sleep quality (SQ) in patients with obesity hypoventilation syndrome (OHS). The aim of this study was to evaluate well-being...
Metabolic regulation of Th17 and Treg cell balance by the mTOR signaling [0.03%]
mTOR信号对Th17和Treg细胞平衡的代谢调控
Zhengzheng Wang,Zhen Xu,Ming Zong et al.
Zhengzheng Wang et al.
The balance between T helper type 17 (Th17) and regulatory T (Treg) cells is crucial for maintaining immune homeostasis. The breakdown of this equilibrium is strongly associated with autoimmune disorders, though the regulatory mechanism of ...
Rikke Thea,Karsten Buschard
Rikke Thea
Comprehensive profiling of candidate biomarkers and immune infiltration landscape in metabolic dysfunction-associated steatohepatitis [0.03%]
代谢功能紊乱相关steatohepatitis的候选生物标志物和免疫浸润特征的全面分析
Zhangliu Jin,Jianyun Cao,Zhaoxun Liu et al.
Zhangliu Jin et al.
Background: The incidence of metabolic dysfunction-associated steatohepatitis (MASH) is increasing, with an incompletely understood pathophysiology involving multiple factors, particularly innate and adaptive immune respo...
Truncated variant rs373056577 confers increased risk of type 2 diabetes and missense variant rs121912717 is associated with hypertriglyceridemia in Bangladeshi population [0.03%]
截断变异体rs373056577增加孟加拉人群2型糖尿病风险,错义变异体rs121912717与高甘油三酯血症相关
Shomoita Sayed,Abdullah Al Saba,Imrul Hasan et al.
Shomoita Sayed et al.
This study investigates the association of allelic and genotypic variations of rs121912717 and rs373056577 within APOA1 and APOA2 genes, respectively with the risk of type 2 diabetes (T2D). In this cross-sectional study, real-time quantitat...