Hepatic activating transcription factor 3 protects against systemic inflammation by attenuating lipotoxicity [0.03%]
活化转录因子3通过减轻脂毒性保护机体免受系统性炎症损伤
Chencheng Hu,Qian Yang,Runzhi Yu et al.
Chencheng Hu et al.
Background: Activating transcription factor 3 (ATF3) is known to play a key role in regulating lipid and lipoprotein metabolism. However, the effects of hepatic ATF3 on systemic inflammation and the underlying mechanisms ...
Efficacy of Momordica charantia in glycaemic control and insulin resistance among patients with prediabetes and type 2 diabetes. A GRADE-adherent meta-analysis of randomised controlled trials [0.03%]
苦瓜在糖尿病前期和2型糖尿病患者血糖控制及胰岛素抵抗中的疗效：基于GRADE的随机对照试验Meta分析
Sphesihle A L Mkhize,Wendy N Phoswa,Phikelelani S Ngubane et al.
Sphesihle A L Mkhize et al.
The prevalence of prediabetes is rising globally, and if untreated, it can lead to a surge in the rate of type 2 diabetes (T2D). Altogether, these conditions are characterised by hyperglycaemia, which promotes cardiovascular complications. ...
Unsaturated alginate oligosaccharides alleviate insulin resistance and fatty liver in non-obese NAFLD mice by regulating bile acid metabolism through gut microbiota [0.03%]
通过调节肠道微生物群胆汁酸代谢缓解非肥胖型NAFLD小鼠的胰岛素抵抗和脂肪肝诱导的不饱和海藻寡糖
Qianqian Cha,Wenrui Zhao,Liyuan Ran et al.
Qianqian Cha et al.
Despite the rising global incidence of non-obese non-alcoholic fatty liver disease (NAFLD), this condition has received limited attention. Unsaturated alginate oligosaccharides (UAOS) have shown promising potential in the management of meta...
Using metabolic syndrome severity in the "real world": Associations with diabetes and cardiovascular disease in all of us vs. NHANES [0.03%]
利用“现实世界”中的代谢综合征严重程度：ALL OF US与NHANES中糖尿病和心血管疾病的关联性研究
Mark D DeBoer,Matthew J Gurka,Marieke K Jones et al.
Mark D DeBoer et al.
Background: While the severity of the metabolic syndrome (MetS) is associated with type 2 diabetes and cardiovascular disease (CVD) in research cohorts, it is unclear if this association remains when using clinically-coll...
The association between the ZJU index and bone mineral density (BMD) among patients with type 2 diabetes mellitus [0.03%]
浙江大学糖尿病综合指数与2型糖尿病患者骨密度的相关性分析
Yuan Zhang,Yali Jing
Yuan Zhang
Background: Previous studies have suggested that type 2 diabetes mellitus (T2DM) is associated with poor bone health, including osteoporosis (OP) and osteopenia. The ZJU index, a novel calculation that integrates fasting ...
Synthetic target trial emulation and predictive modeling of amylin-pathway therapies for obesity and type 2 diabetes [0.03%]
合成目标试验模拟和预测性建模以用于肥胖症和2型糖尿病的胰岛素超家族成员集落激素通路药物治疗
Faisal A Al-Harbi,Ahmed K Alsaif,Atheer G Almutairi et al.
Faisal A Al-Harbi et al.
Introduction: Amylin-pathway therapies represent a novel therapeutic class for obesity and type 2 diabetes, however head-to-head comparative data and long-term outcome predictions remain limited. We conducted target trial...
Pharmacokinetics and metabolic effects of ketone monoester supplementation: The first simultaneous CKM and CGM study under normal diet and activities [0.03%]
酮单酯补充的药代动力学和代谢效应：正常饮食和活动下的首次同时CKM和CGM研究
Toshiya Miyatsu,Connor Tate,Jeremy McAdam et al.
Toshiya Miyatsu et al.
Exogenous ketone supplementation has gained attention for its potential health and performance benefits, yet its real-world pharmacokinetics and metabolic effects remain underexplored. This study investigated the pharmacokinetics of ketone ...
Liver transplantation in the era of obesity: A metabolic public health crisis meets a surgical frontier [0.03%]
肥胖时代下的肝脏移植：代谢性公共卫生危机与外科前沿相遇
Sofia Rozani,Maria Dalamaga,Georg Weber et al.
Sofia Rozani et al.
The global obesity epidemic has reshaped the landscape of liver transplantation (LT). Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the leading indications for LT in Western countries, while excess adipo...
Deliberating the striking effect of dual GLP-1R and GIPR agonists on "Diabesity" in light of precision medicine and pharmacogenomics [0.03%]
精准医疗和药物基因组学视角下双GLP-1受体和GIP受体激动剂对“糖尿病肥胖症”的作用机制探讨
Angeliki Margoni,Kostas A Papavassiliou,Athanasios G Papavassiliou
Angeliki Margoni
Elevated fasting glucose is common in lung cancer patients undergoing 18F-FDG PET/CT: A brief report [0.03%]
肺癌患者进行18F-FDG PET/CT检查时常见空腹血糖升高：简报
Bojan Bojanic,Moritz Schwyzer,Thomas Sartoretti et al.
Bojan Bojanic et al.
Objectives: To characterize glycemic profiles among patients with lung cancer undergoing standardized capillary fasting blood glucose (cFBG) assessment prior to fluorodeoxyglucose positron emission tomography/computed tom...