Prediabetes screening: Questionable benefits in the golden years [0.03%]
糖尿病前期筛查：金年齡段的效益 questionable
Dimitrios Tsilingiris,Natalia G Vallianou,Maria Dalamaga
Dimitrios Tsilingiris
Irrespective of the definition and diagnostic criteria used, the term prediabetes denotes a state of dysmetabolism with a high risk of progression to diabetes mellitus. Although diabetes-related complications may already be evident among in...
Non-alcoholic fatty liver disease is a risk factor for occurrence of hepatocellular carcinoma after sustained virologic response in chronic hepatitis C patients: A prospective four-years follow-up study [0.03%]
非酒精性脂肪肝是慢性丙型肝炎患者持续病毒学治愈后发生肝细胞癌的危险因素：一项四年的前瞻性研究报告
Dong Ji,Guo-Feng Chen,Xiao-Xia Niu et al.
Dong Ji et al.
Background and aim: The incidence of hepatocellular carcinoma (HCC) decreases significantly in chronic hepatitis C (CHC) patients with sustained virologic response (SVR) after pegylated-interferon plus ribavirin (PR) or d...
Zhuoying Yang,Zhuo-Xian Meng
Zhuoying Yang
Sodium-glucose co-transporter-2 inhibitors in patients with type 2 diabetes mellitus without established cardiovascular disease: Do they have a role in primary prevention? [0.03%]
钠葡萄糖共转运体-2抑制剂在无已知心血管疾病2型糖尿病患者中用于一级预防的作用？
Shailaja Kale,Abd A Tahrani
Shailaja Kale
Most guidelines and cardiovascular outcome trials (CVOTs) focus on secondary prevention of cardiovascular disease (CVD) in type 2 diabetes mellitus (T2DM). Patients with T2DM without established CVD (eCVD) also form a critical cohort, for w...
Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor: In the heart of the problem [0.03%]
索塔格利弗雷扎尼恩，一种SGLT1和SGLT2双重抑制剂：治疗心脏病的新方法
Natalia G Vallianou,Gerasimos Socrates Christodoulatos,Dimitris Kounatidis et al.
Natalia G Vallianou et al.
Possible mechanisms of the hypoglycaemic effect of artesunate: Gender implication [0.03%]
青蒿素低血糖作用的可能机制及性别差异
Abdullateef Isiaka Alagbonsi,Toyin Mohammad Salman,Sheu Oluwadare Sulaiman et al.
Abdullateef Isiaka Alagbonsi et al.
Background: We investigated the mechanism of artesunate's glucose-modulating effect especially with gender implication. Methods: Twenty...
The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA [0.03%]
3-羟基丙酸和1,3-propanediol的存在提示了甘油转化为乙酰辅酶A的新途径
Eunsook S Jin,Min H Lee,Craig R Malloy
Eunsook S Jin
Background: In our recent study using [U-13C3]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol ...
Fasting plasma metabolomic profiles are altered by three days of standardized diet and restricted physical activity [0.03%]
标准化饮食和限制身体活动3天可改变受试者的空腹血浆代谢物谱式
Laura Pyle,Anne-Marie Carreau,Haseeb Rahat et al.
Laura Pyle et al.
Objective: Few studies have examined the effects of participants' diet and activity prior to sample collection on metabolomics profiles, and results have been conflicting. We compared the effects of overnight fasting with...
Comment on: Non-esterified fatty acids and telomere length in older adults [0.03%]
关于非酯化脂肪酸与老年人端粒长度的关系的述评
Bilal Katipoglu,Mehmet Ilkin Naharci
Bilal Katipoglu
Gut microbiome and Mediterranean diet in the context of obesity. Current knowledge, perspectives and potential therapeutic targets [0.03%]
肠道微生物组与地中海饮食在肥胖背景下的研究：现有知识、展望及潜在治疗靶点
Christina Tsigalou,Afroditi Paraschaki,Alexandros Karvelas et al.
Christina Tsigalou et al.
Mediterranean Diet has been recognized as one of the healthiest and sustainable dietary patterns worldwide, based on the food habits of people living in the Mediterranean region. It is focused on a plant-based cuisine combining local agricu...