Objective prenatal sleep and adverse childhood experiences in a proof-of-concept observational mixed methods study [0.03%]
一项概念验证性观察研究：产前睡眠与不良童年经历之间的关系
Jessica Rohr,Bishal Lamichhane,Ashutosh Sabharwal et al.
Jessica Rohr et al.
Adverse childhood experiences (ACEs) have been proposed as a contributor to maternal health risk, and sleep is one pathway through which early adversity may influence physiological functioning during pregnancy. We examined whether ACEs were...
A distribution-aware semi-supervised pipeline for cost-effective neuron segmentation [0.03%]
一种分布感知的半监督管道用于成本效益神经元分割
Yanchao Zhang,Hao Zhai,Jinyue Guo et al.
Yanchao Zhang et al.
Semi-supervised learning offers a cost-effective approach for neuron segmentation in electron microscopy (EM) volumes. This technique leverages unlabeled data to regularize supervised training for robust neuron boundary prediction. However,...
Caloric restriction modifies small RNA profiles and engages age-related molecular pathways in the CALERIE trial [0.03%]
热量限制可改变小RNA谱型并激活CALERIE实验中与年龄相关的分子通路
Melissa C Orenduff,Kim M Huffman,Daniel W Belsky et al.
Melissa C Orenduff et al.
Caloric restriction (CR) extends lifespan and enhances healthspan across species. In humans, the CALERIE Phase 2 trial demonstrated that CR improves inflammation, cardiometabolic health, and molecular aging. To explore underlying mechanisms...
Early postoperative acute kidney injury prediction in patients with acute type A aortic dissection [0.03%]
急性A型主动脉夹层患者早期术后急性肾损伤的预测
Ling Chen,Yichao Pan,Huaijian Zhang et al.
Ling Chen et al.
Acute kidney injury (AKI) is a frequent and serious complication following surgery for acute type A aortic dissection (AAD), often leading to delayed treatment and poor outcomes. This multicenter study developed and validated a predictive n...
Miles Walter Churchland,Jordi Garcia-Ojalvo
Miles Walter Churchland
Training highly recurrent networks is a technical challenge: gradient-based methods suffer from exploding or vanishing gradients, while purely evolutionary searches converge slowly. We introduce a hybrid, gradient-free optimization framewor...
Transcranial microtesla magnetic fields suppress neuroinflammation and neuronal oxidative stress burden [0.03%]
低频经颅磁刺激抑制神经炎症和氧化压力负荷
Nhu Nguyen,Nathan R Brady,Greg A Timblin et al.
Nhu Nguyen et al.
Neuroinflammation is a major driver of neurodegenerative and psychiatric disease, yet current therapies have limited brain penetration and efficacy. We investigated microtesla magnetic therapy (MMT), a brief transcranial exposure to time-va...
Sara C Pryor,Rebecca J Barthelmie
Sara C Pryor
Hundreds of thousands of wind turbines and billions of solar photovoltaic (PV) panels are operating worldwide. Reliability, power production and operations, and maintenance costs for these electricity generation sources depend on operating ...
The MO25 protein Pmo25 functions in contractile ring stability and Sid2 localization during cytokinesis [0.03%]
MO25蛋白Pmo25在有丝分裂胞质分裂期间收缩环稳定性和Sid2定位中的功能作用
Yanfang Ye,Sha Zhang,Jack R Gregory et al.
Yanfang Ye et al.
Mouse protein-25 (MO25) family proteins are crucial in development and morphogenesis from plants to humans. The fission yeast MO25 protein Pmo25 is essential for cell polarity and division. However, how Pmo25 regulates cytokinesis remains l...
Irteza Qayoom,Faisal Zahoor Jan,Irfan Rashid et al.
Irteza Qayoom et al.
Microplastics, recognized as an emerging and pervasive environmental contaminant, have been detected in remote cryospheric regions such as Antarctica, Arctic, Andes, Alps, and High Asia. This review synthesizes current knowledge on micropla...
Mutual effects of ablation and ice temperature in a firn-free glacier: Observations from Aug 1st glacier on northeast Tibetan plateau [0.03%]
无firn冰川消融与冰温的相互作用：青藏高原东北部八一冰川的观测结果
Guohua Liu,Rensheng Chen,Chuntan Han et al.
Guohua Liu et al.
Glacier stability depends on the interaction between ice temperature and ablation, processes mediated by firn cover. Although firn-covered glaciers have been extensively investigated, firn-free glacier dynamics remain less clear. This study...