Impact of Implementation of Risk Calculators for the Selection of Extended Pelvic Lymph Node Dissection Candidates: 20-year Experience from a Tertiary Referral Centre [0.03%]
风险计算器实施对扩大盆腔淋巴结清扫术适应证选择的影响:一家三级转诊中心20年的经验
Francesco Barletta,Simone Scuderi,Pietro Scilipoti et al.
Francesco Barletta et al.
Background and objective: Several models predicting the lymph node invasion (LNI) risk in radical prostatectomy (RP) patients have been proposed to identify extended pelvic lymph node dissection (ePLND) candidates. We hyp...
Magnetic Resonance Imaging-guided Focal Boost to Intraprostatic Lesions Using External Beam Radiotherapy for Localized Prostate Cancer: A Systematic Review and Meta-analysis [0.03%]
磁共振引导下的外照射前列腺癌局灶病灶放疗的系统评价和meta分析
Darren M C Poon,Jing Yuan,Bin Yang et al.
Darren M C Poon et al.
Context: It is anticipated that a focal boost to intraprostatic lesions (IPLs) using external beam radiotherapy (EBRT) guided by magnetic resonance imaging (MRI) will increase biochemical disease-free survival (bDFS) with...
Higher Preoperative Maximum Standardised Uptake Values Are Associated with a Higher Risk of Metastases After Robot-assisted Radical Prostatectomy for Patients Undergoing 68Ga-PSMA-11 and 18F-DCFPyL Positron Emission Tomography/Computed Tomography [0.03%]
术前较高的最大标准化摄取值与接受68Ga-PSMA-11和18F-DCFPyL正电子发射断层扫描/计算机断层扫描的机器人辅助根治性前列腺切除术患者的转移风险较高有关
K C C de Bie,M F Creanza,Y J L Bodar et al.
K C C de Bie et al.
Background and objective: Prostate-specific membrane antigen (PSMA) expression on positron emission tomography/computed tomography (PET/CT), semiquantitatively expressed as the standardised uptake value (SUVmax), is incre...
Predictive Value of Prior Non-muscle-invasive Bladder Cancer for the Effectiveness of Neoadjuvant Chemotherapy in Localized Muscle-invasive Bladder Cancer: A Real-world Analysis of the BLADRAC Cohort [0.03%]
非肌层浸润性膀胱癌对肌层浸润性膀胱癌新辅助化疗效果预测价值的实证研究:BLADRAC队列分析
Elisabeth Grobet-Jeandin,Elliott Diamant,Pierre-Etienne Gabriel et al.
Elisabeth Grobet-Jeandin et al.
Background and objective: It remains currently unknown whether the effectiveness of neoadjuvant chemotherapy (NAC) before radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC) is the same in patients with or w...
Docetaxel with Androgen Deprivation and Radiotherapy in High-risk Localized Prostate Cancer: An ICECaP Individual Patient Data Meta-analysis [0.03%]
一项ICECaP个体患者数据Meta分析:高危局限性前列腺癌患者多西他赛联合雄激素剥夺和放疗的治疗效果
Praful Ravi,Lucia Kwak,Wanling Xie et al.
Praful Ravi et al.
Background and objective: The addition of docetaxel to radiotherapy (RT) and long-term androgen deprivation therapy (ADT) is not a standard of care for the treatment of high-risk localized prostate cancer (HRLPC). We perf...
Clinical Evaluation of a Novel Deintensified Surveillance Protocol for Low-risk Non-muscle-invasive Bladder Cancer: A Prospective Study in 250 Patients [0.03%]
低危非肌层浸润性膀胱癌新型降级监测方案的临床评价:一项前瞻性研究(涉及250例患者)
Chandrarajan Premal Shah,Jennifer Gray,Tanya Lord-McKenzie et al.
Chandrarajan Premal Shah et al.
Background and objective: Recent Edinburgh-based research demonstrated high negative predictive value (NPV) for urinary dipstick testing for haematuria (UDH) in low-risk bladder cancer surveillance. This enabled a new pro...
Prostate-specific Antigen Nadir and Time to Nadir Predict Recurrence in Postprostatectomy Patients Treated with Salvage Radiotherapy Without Androgen Deprivation Therapy [0.03%]
根治术后未行雄激素剥夺治疗序贯挽救放疗患者的生化复发与前列腺特异性抗原最低值及达到最低值时间的关系
Federico Mastroleo,Riccardo Villa,Mattia Zaffaroni et al.
Federico Mastroleo et al.
Background and objective: Salvage radiotherapy (SRT) is often curative in men with biochemical recurrence (BCR) after radical prostatectomy (RP); however, a subset experiences progression. While the depth of prostate-spec...
Re: M. Roupret, A. Bertaut, G. Pignot, et al. ALBAN (GETUG-AFU 37): A Phase 3, Randomized, Open-label, International Trial of Intravenous Atezolizumab and Intravesical Bacillus Calmette-Guérin (BCG) Versus BCG Alone in BCG-naive High-risk, Non-muscle-invasive bladder cancer (NMIBC). Ann Oncol. In press. https://doi.org/10.1016/j.annonc.2025.09.017 [0.03%]
ALBAN(GETUG-AFU 37):一项 III 期、随机、开放标签、国际多中心试验,评估阿特珠单抗联合卡介苗与单独卡介苗治疗高危初治非肌层浸润性膀胱癌患者的疗效和安全性。Ann Oncol. 在线发表。https://doi.org/10.1016/j.annonc.2025.09.017
David DAndrea,Shahrokh F Shariat
David DAndrea
Benchmarking Large Language Models Against Multidisciplinary Tumor Boards in Urological Oncology: Results from the Blinded, Prospective CONCORDIA Study [0.03%]
泌尿肿瘤学多学科肿瘤委员会对照大型语言模型:来自盲法前瞻性CONCORDIA研究的结果
Emily Rinderknecht,Maximilian Haas,Marco J Schnabel et al.
Emily Rinderknecht et al.
Background and objective: Multidisciplinary tumor boards (MTBs) are the gold standard for oncological treatment planning, but their implementation is resource intensive. Large language models (LLMs) such as ChatGPT-4 and ...
Prostate-specific Membrane Antigen Positron Emission Tomography Versus Conventional Imaging for Preoperative Staging High-risk Prostate Cancer Patients Undergoing Surgery for cN0M0 Disease: An European Association of Urology-Young Academic Urologists Prostate Cancer Working Group Multi-institutional Study [0.03%]
前列腺癌手术前分期:高危前列腺癌患者使用前列腺特异性膜抗原正电子发射断层扫描与常规成像的比较(欧洲泌尿外科协会-青年学术泌尿外科医师协会前列腺癌工作组多中心研究)
Lorenzo Bianchi,Matteo Droghetti,Calogero Catanzaro et al.
Lorenzo Bianchi et al.
Background and objective: Current guidelines strongly recommend prostate-specific membrane antigen positron emission tomography (PSMA-PET) for staging high-risk prostate cancer (PCa) patients. This study aims to evaluate ...