A Single Educational Seminar Increases Confidence and Decreases Dropout from Active Surveillance by 5 Years After Diagnosis of Prostate Cancer [0.03%]
一项教育研讨会可增加患者的信心并减少前列腺癌诊断后五年内接受主动监测的患者流失数量
Netty Kinsella,Kerri Beckmann,Declan Cahill et al.
Netty Kinsella et al.
Background: Researchers remain divided on the major causes of dropout from active surveillance (AS), with rates of up to 38% among men with no evidence of prostate cancer (PC) progression. ...
Controlled Clinical Trial
European urology oncology. 2019 Jul;2(4):464-470. DOI:10.1016/j.euo.2018.09.007 2019
Defining the Most Informative Intermediate Clinical Endpoints for Predicting Overall Survival in Patients Treated with Radical Prostatectomy for High-risk Prostate Cancer [0.03%]
预测高危前列腺癌根治术后总生存的最有价值的中间临床终点指标的选择
Alberto Martini,Giorgio Gandaglia,R Jeffrey Karnes et al.
Alberto Martini et al.
Background: Given the prolonged natural history of clinically localized, high-risk prostate cancer, there is a need for the identification of intermediate clinical endpoints (ICEs) to predict long-term overall survival (O...
Adjuvant Radiation Therapy After Radical Nephrectomy in Patients with Localized Renal Cell Carcinoma: A Systematic Review and Meta-analysis [0.03%]
根治性肾切除术后局灶期肾癌患者辅助放疗的系统评价和 meta 分析
Iván A Rodríguez-Fernández,Laura Rodríguez-Romo,David Hernandez-Barajas et al.
Iván A Rodríguez-Fernández et al.
Context: Adjuvant radiation therapy has been recommended for patients at higher risk of relapse from renal cell carcinoma (RCC) to improve disease-free survival (DFS) and overall survival (OS) after radical nephrectomy. ...
Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy: A Meta-analysis of Oncologic, Perioperative, and Complication-related outcomes [0.03%]
机器人辅助根治性膀胱切除术与开放性根治性膀胱切除术的对比：一项关于肿瘤学、围手术期和并发症相关结果的meta分析研究
Raj Satkunasivam,Christopher T Tallman,Jennifer M Taylor et al.
Raj Satkunasivam et al.
Robot-assisted radical cystectomy (RARC) is increasingly being used to treat muscle-invasive bladder cancer in an attempt to improve functional outcomes and complication rates over open radical cystectomy (ORC). We performed a meta-analysis...
Detection of Relapse by Low-dose Computed Tomography During Surveillance in Stage I Testicular Germ Cell Tumours [0.03%]
低剂量CT在I期睾丸生殖细胞肿瘤监测中的复发检测能力
Peter Chung,Martin E O&#x;Malley,Michael A S Jewett et al.
Peter Chung et al.
Background: Standard-dose computed tomography (SDCT) scans are associated with radiation exposure during stage I testicular cancer surveillance. Objective...
Mannose Receptor-positive Macrophage Infiltration Correlates with Prostate Cancer Onset and Metastatic Castration-resistant Disease [0.03%]
甘露糖受体阳性巨噬细胞浸润与前列腺癌发生和转移性去势抵抗性疾病的关系
Jelani C Zarif,Javier A Baena-Del Valle,Jessica L Hicks et al.
Jelani C Zarif et al.
Background: M2 tumor-associated macrophages (M2-TAMs) can suppress inflammation in the tumor microenvironment and have been reported to modulate cancer progression. We and others have previously reported M2-TAM infiltrati...
Feasibility of a Mobile Health Application To Monitor Recovery and Patient-reported Outcomes after Robot-assisted Radical Prostatectomy [0.03%]
移动健康应用程序监测机器人辅助根治性前列腺切除术术后恢复和患者报告结果的可行性研究
André Belarmino,Ryan Walsh,Mark Alshak et al.
André Belarmino et al.
A mobile application (app) designed on the basis of a literature review and interviews with urologic oncologists was created to help streamline robot-assisted radical prostatectomy care and in compliance with quality indicators. Use of the ...
Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer [0.03%]
EC-8042通过转录重编程抑制ERG阳性前列腺癌肿瘤起始类干细胞的作用机制研究
Dheeraj Shinde,Domenico Albino,Marita Zoma et al.
Dheeraj Shinde et al.
Background: The TMPRSS2-ERG gene fusion is the most frequent genetic rearrangement in prostate cancers and results in broad transcriptional reprogramming and major phenotypic changes. Interaction and cooperation of ERG an...
Magnetic Resonance Imaging-guided In-bore and Magnetic Resonance Imaging-transrectal Ultrasound Fusion Targeted Prostate Biopsies: An Adjusted Comparison of Clinically Significant Prostate Cancer Detection Rate [0.03%]
磁共振引导的腔内和磁共振-经直肠超声融合靶向前列腺活检：临床显著性前列腺癌检测率的校正对比研究
Daniel N Costa,Kenneth Goldberg,Alberto Diaz de Leon et al.
Daniel N Costa et al.
Background: With the increasing adoption of targeted prostate biopsies, it becomes important to understand the strengths and shortcomings of the techniques available for targeting suspicious lesions. ...
Observational Study
European urology oncology. 2019 Jul;2(4):397-404. DOI:10.1016/j.euo.2018.08.022 2019
Delaying Radical Cystectomy After Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer is Associated with Adverse Survival Outcomes [0.03%]
肌层浸润性膀胱癌新辅助化疗后延迟根治性膀胱切除与预后不良有关
Luca Boeri,Matteo Soligo,Igor Frank et al.
Luca Boeri et al.
Background: Delaying radical cystectomy (RC) after a diagnosis of muscle-invasive bladder cancer (MIBC) has been associated with adverse survival. However, data are lacking regarding the impact of RC delay in patients rec...