Evidence-based Assessment of Current and Emerging Bladder-sparing Therapies for Non-muscle-invasive Bladder Cancer After Bacillus Calmette-Guerin Therapy: A Systematic Review and Meta-analysis [0.03%]
基于证据的巴氏消毒法治疗后非肌层浸润性膀胱癌当前和新兴保膀胱疗法的评估:系统回顾和meta分析
Ashish M Kamat,Seth P Lerner,Michael ODonnell et al.
Ashish M Kamat et al.
Context: Currently, there is no standard of care for patients with non-muscle-invasive bladder cancer (NMIBC) who recur despite bacillus Calmette-Guerin (BCG) therapy. Although radical cystectomy is recommended, many pati...
Chromophobe Renal Cell Carcinoma Aggressiveness and Immuno-oncology Therapy: How to Distinguish the Good One from the Bad One [0.03%]
肾透明细胞癌的侵袭性与免疫肿瘤学治疗:如何区分好坏
Rodolfo Montironi,Alessia Cimadamore,Riuko Ohashi et al.
Rodolfo Montironi et al.
Diagnostic Performance of Vesical Imaging Reporting and Data System for the Prediction of Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis [0.03%]
膀胱影像报告和数据系统判断肌层浸润性膀胱癌的诊断性能:一项系统综述和 meta 分析
Sungmin Woo,Valeria Panebianco,Yoshifumi Narumi et al.
Sungmin Woo et al.
Context: A noninvasive multiparametric magnetic resonance imaging (MRI)-based scoring system for predicting muscle-invasive bladder cancer (MIBC), the "Vesical Imaging Reporting and Data System" (VI-RADS), was recently de...
Factors Influencing Variability in the Performance of Multiparametric Magnetic Resonance Imaging in Detecting Clinically Significant Prostate Cancer: A Systematic Literature Review [0.03%]
多参数磁共振成像检测临床显著性前列腺癌性能变异的影响因素:系统文献回顾
Armando Stabile,Francesco Giganti,Veeru Kasivisvanathan et al.
Armando Stabile et al.
Context: There is a lack of comprehensive data regarding the factors that influence the diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) to detect and localize clinically significant prostate canc...
Carcinogen Biomarkers in the Urine of Electronic Cigarette Users and Implications for the Development of Bladder Cancer: A Systematic Review [0.03%]
关于电子烟使用者尿液中的致癌生物标志物及其对膀胱癌发展的潜在影响的系统评价
Marc A Bjurlin,Richard S Matulewicz,Timothy R Roberts et al.
Marc A Bjurlin et al.
Context: Use of electronic cigarettes (e-cigarettes) has rapidly increased despite unclear longitudinal health effects. Once thought to be a safer alternative to tobacco smoke, it is possible that e-cigarettes expose the ...
Defects in DNA Repair Genes Confer Improved Long-term Survival after Cisplatin-based Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer [0.03%]
DNA修复基因的缺陷可提高肌侵袭性膀胱癌顺铂新辅助化疗的长期生存率
Benjamin Miron,Jean H Hoffman-Censits,Fern Anari et al.
Benjamin Miron et al.
Cisplatin-based neoadjuvant chemotherapy (NAC) has demonstrated an overall survival (OS) benefit in muscle-invasive bladder cancer (MIBC). However, only a subset of patients (25-50%) have a pathologic complete response at cystectomy. Using ...
Re: Karl H. Tully, David-Dan Nguyen, Peter Herzog, et al. Risk of Dementia and Depression in Young and Middle-aged Men Presenting with Nonmetastatic Prostate Cancer Treated with Androgen Deprivation Therapy. Eur Urol Oncol. In press. http://dx.doi.org/10.1016/j.euo.2019.08.003 [0.03%]
雄激素剥夺治疗对前列腺癌患者认知功能影响的纵向研究:DAISY队列报告
Charalampos Fragkoulis,Ioannis Glykas,Georgios Papadopoulos et al.
Charalampos Fragkoulis et al.
Detection of Recurrent Prostate Cancer Using Prostate-specific Membrane Antigen Positron Emission Tomography in Patients not Meeting the Phoenix Criteria for Biochemical Recurrence After Curative Radiotherapy [0.03%]
前列腺根治性放疗后不符合凤凰城标准生化复发的患者中使用前列腺特异性膜抗原正电子发射断层扫描检测前列腺癌复发
Bernard H E Jansen,Pim J van Leeuwen,Maurits Wondergem et al.
Bernard H E Jansen et al.
Biochemical recurrence of prostate cancer (PCa) after curative radiotherapy is defined as a prostate-specific antigen (PSA) rise of ≥2 ng/ml above the nadir ("Phoenix criteria", 2005). With the introduction of prostate-specific membrane an...
Phase II Trial of Enzalutamide and Androgen Deprivation Therapy with Salvage Radiation in Men with High-risk Prostate-specific Antigen Recurrent Prostate Cancer: The STREAM Trial [0.03%]
高危前列腺癌根治术后PSA复发的恩扎卢胺联合去势治疗及挽救性放疗疗效观察:STREAM试验报告
Rhonda L Bitting,Patrick Healy,Daniel J George et al.
Rhonda L Bitting et al.
Background: Salvage external beam radiotherapy (RT) with androgen deprivation therapy (ADT) improves survival over RT in men with prostate cancer (PC) and rising prostate-specific antigen (PSA) levels after radical prosta...
Clinical Trial
European urology oncology. 2021 Dec;4(6):948-954. DOI:10.1016/j.euo.2020.01.005 2021
Urothelial Cancers with Small Cell Variant Histology Have Confirmed High Tumor Mutational Burden, Frequent TP53 and RB Mutations, and a Unique Gene Expression Profile [0.03%]
具有小细胞变异组织学的尿路上皮癌具有较高的肿瘤突变负荷、频繁的TP53和RB基因突变以及独特的基因表达谱
Jean Hoffman-Censits,Woonyoung Choi,Sumanta Pal et al.
Jean Hoffman-Censits et al.
Although predominantly urothelial, some bladder cancer and upper tract urothelial cancer (BC/UTUC) harbor histologic variants. Small cell BC (SCBC) variants comprised ˜5% of The Cancer Genome Atlas BC cohort, with a poor prognosis. We desc...