Germline DNA Repair and Immune-metabolic Alterations Suggest a Potentially Distinct Form of Early-onset Prostate Cancer in Men of African Descent [0.03%]
非洲男性系谱DNA修复和免疫-代谢变化提示一种潜在的独特的早发性前列腺癌形式
Jean-Samuel Loger,Emeline Colomba,Alexis Vallard et al.
Jean-Samuel Loger et al.
Background and objective: Early-onset prostate cancer (PCa) is more frequent in men of African descent; yet, the biological mechanisms underlying susceptibility remain unclear. While most germline studies have focused on ...
Reply to Constance Huck, Paul Sargos, and Alberto Bossi's Letter to the Editor re: Markus Graefen, Fabian Falkenbach, Tobias Maurer, et al. Best Systemic Therapy With or Without Radical Prostatectomy in the Management of Men With Oligometastatic Prostate Cancer: The RAMPP Randomised Controlled Trial. Eur Urol. In press. https://doi.org/10.1016/ [0.03%]
关于康斯坦茨·赫克、保罗·萨戈斯和阿尔贝托·博西来信的回复针对马库斯·格拉芬、法比安·冯克巴赫、 Tobias Maurer 等人文章《系统性治疗联合或不联合根治性前列腺切除术在寡转移性前列腺癌患者中的应用：RAMPP 随机对照试验》欧洲泌尿外科杂志，在线发表。DOI:10.1016/j.eururo.2021.09.048
Fabian Falkenbach,Markus Graefen,Burkhard Beyer
Fabian Falkenbach
Penile Cancer Survivorship: Research Gaps in Psychosocial Health and Sexual Quality of Life [0.03%]
阴茎癌幸存者身心和社会健康及性生活质量的研究空白点
Cameron J Britton,Omar Almidani,Avi S Baskin et al.
Cameron J Britton et al.
We discuss the limited evidence in the literature on the psychosocial health and sexual quality of life of survivors of penile cancer and suggest some future directions for research in this setting. ...
Assessment of Pathologic Response in Kidney Cancer: Back to the Microscope for Now [0.03%]
肾脏癌的病理评估：目前只能借助显微镜了
Axel Bex,Grant D Stewart
Axel Bex
Extending Current Guideline-recommended Prostate-specific Antigen Density Thresholds for Improving Benefit/Harm Balance in Risk-based Magnetic Resonance Imaging-directed Prostate Cancer Diagnosis, from the Community-based Multicentre MR-PROPER Study [0.03%]
基于风险的磁共振导向前列腺癌诊断中，为改善利弊平衡而对现行指南推荐的前列腺特异性抗原密度阈值进行改进--来自社区多中心MR-PROPER研究的结果分析
Anne M A Prinsen,Ivo M Wagensveld,Daniel F Osses et al.
Anne M A Prinsen et al.
Background and objective: International guidelines recommend a risk-based magnetic resonance imaging (MRI)-directed diagnostic pathway in prostate cancer (PCa) suspected biopsy-naïve men to reduce overdiagnosis. Prostate...
Re: Markus Graefen, Fabian Falkenbach, Tobias Maurer, et al. Best Systemic Therapy With or Without Radical Prostatectomy in the Management of Men With Oligometastatic Prostate Cancer: The RAMPP Randomised Controlled Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2025.09.4144 [0.03%]
马库斯·格拉芬、法比安·法尔肯巴赫、托比亚斯·毛勒等。寡转移性前列腺癌患者系统治疗联合或不联合根治性前列腺切除术的疗效：RAMPP随机对照试验。Eur Urol. 在线发表。https://doi.org/10.1016/j.eururo.2025.09.4144
Constance Huck,Paul Sargos,Alberto Bossi
Constance Huck
Bladder EpiCheck triggered Photodynamic Diagnosis biopsies Detect High-grade Bladder Cancer Recurrences Missed by White Light Cystoscopy [0.03%]
基于膀胱EpiCheck触发的光动力学诊断活检检测出白光膀胱镜遗漏的高级别复发性膀胱癌
Paramananthan Mariappan,Jasmin Hart-Brooke,Rebecca Sparks et al.
Paramananthan Mariappan et al.
Background and objective: White light cystoscopy (WLC) misses ∼70% of carcinoma in situ bladder recurrences that could be identified via photodynamic diagnosis (PDD). The Bladder EpiCheck (BE) test has high sensitivity a...
Pathologic Response to Immunotherapy Is Associated with Survival in Patients Undergoing Delayed Nephrectomy for Metastatic Renal Cell Carcinoma [0.03%]
延迟肾切除术的转移性肾细胞癌患者的免疫治疗病理反应与生存相关性研究
Yash S Khandwala,Stephen W Reese,Burcin A Ucpinar et al.
Yash S Khandwala et al.
Background and objective: The role of consolidative nephrectomy (CN) in metastatic renal cell carcinoma (mRCC) patients treated with immune checkpoint inhibitors remains unknown. As patients derive variable benefit from i...
A Novel Transurethral Robotic Platform for Performing En Bloc Resection of Bladder Tumour: Results from the First Phase of the VIABLE Trial [0.03%]
VIABLE试验第一阶段的成果：一种用于整块切除膀胱肿瘤的经尿道机器人平台的新方法
Jeremy Yuen-Chun Teoh,Francesco Maria Bracco,Julius Ho-Fai Wong et al.
Jeremy Yuen-Chun Teoh et al.
The Virtuoso Endoscopy System (VES) is a novel robotic surgical system designed for transurethral excision of bladder lesions. In this first-in-human study, we evaluated the feasibility of using the VES to perform safe and effective excisio...
Circulating Tumor DNA in Muscle-invasive Bladder Cancer: Promise, Pitfalls, and Path Forward [0.03%]
肌层浸润性膀胱癌的循环肿瘤DNA：希望、挑战及未来方向
Clara Cerrato,Morgan Rouprêt,Maria Carmen Mir
Clara Cerrato
Recent results from IMvigor 011 constitute the first prospective, randomized validation of a therapeutic strategy guided by circulating tumor DNA (ctDNA) status in urothelial cancer. We discuss the promise of ctDNA for guiding treatment dec...