Jarno M A Tanskanen,Annika Ahtiainen,Jari A K Hyttinen
Jarno M A Tanskanen
Biological neuronal cells communicate using neurochemistry and electrical signals. The same phenomena also allow us to probe and manipulate neuronal systems and communicate with them. Neuronal system malfunctions cause a multitude of sympto...
Artificial Intelligence, Brains, and Beyond: Imperial College London Neurotechnology Symposium, 2020 [0.03%]
人工智能、大脑和更远的未来：帝国理工学院神经技术研讨会，2020年
Anna Tarasenko,Mikheil Oganesyan,Daryna Ivaskevych et al.
Anna Tarasenko et al.
In this report, we give an overview of the proceedings from the online Imperial College London Neurotechnology Symposium 2020. The first part deals with the fundamentals of how artificial intelligence (AI) can be used to inform research fra...
Masayuki Yamashita
Masayuki Yamashita
Background: To study the molecular mechanism of galvanotropism in vitro, the strength of an electric field (EF) must be controlled precisely. In this study, I present a culture system that supplies an EF of constant strength by regulating t...
Physiological Effects of the Electrogenic Current Generated by the Na+/K+ Pump in Mammalian Articular Chondrocytes [0.03%]
哺乳动物关节软骨细胞中Na+/K+泵产生的电生电流的生理效应
Mary M Maleckar,Pablo Martín-Vasallo,Wayne R Giles et al.
Mary M Maleckar et al.
Background: Although the chondrocyte is a nonexcitable cell, there is strong interest in gaining detailed knowledge of its ion pumps, channels, exchangers, and transporters. In combination, these transport mechanisms set the resting potenti...
A Role for Monosaccharides in Nucleation Inhibition and Transport of Collagen [0.03%]
单糖在胶原蛋白成核抑制和运输中的作用
Cassandra L Martin,Michael R Bergman,Leila F Deravi et al.
Cassandra L Martin et al.
Background: Collagenous tissues are composed of precisely oriented, tightly packed collagen fibril bundles to confer the maximal strength within the smallest volume. While this compact form benefits mobility, it consequentially restricts va...
Differential Cell Death and Regrowth of Dermal Fibroblasts and Keratinocytes After Application of Pulsed Electric Fields [0.03%]
脉冲电场作用后皮肤成纤维细胞和角质形成细胞的差异性死亡与再生修复
Bodhisatwa Das,Anil Shrirao,Alexander Golberg et al.
Bodhisatwa Das et al.
Background: High-powered pulsed electric fields (PEF) may be used for tissue debridement and disinfection, while lower PEF intensities may stimulate beneficial cellular responses for wound healing. We investigated the dual effects of nonuni...
Pharmacokinetics and Biodistribution Analysis of Small Interference RNA for Silencing Tissue Transglutaminase-2 in Celiac Disease After Oral Administration in Mice Using Gelatin-Based Multicompartmental Delivery Systems [0.03%]
基于明胶的多隔室传递系统口服给药后小干扰RNA在小鼠体内的药代动力学及组织分布研究（针对乳糜泻组织转谷氨酰胺酶-2基因沉默）
Husain Z Attarwala,Kanika Suri,Mansoor M Amiji
Husain Z Attarwala
Background: RNA interference (RNAi) therapy has tremendous potential in treating diseases that are characterized by overexpression of genes. However, the biggest challenge to utilize the therapy is to engineer delivery systems that can effi...