Luis A Pardo
Luis A Pardo
Bioelectricity goes far beyond electrical signaling in the nervous system, but this was initially not obvious for me. This article describes the journey from studying the biophysics of ion channels in classical electrically excitable tissue...
Modeling Electrostatic Charge Shielding Induced by Cationic Drug Carriers in Articular Cartilage Using Donnan Osmotic Theory [0.03%]
利用唐南渗透理论对阳离子药物载体在关节软骨中引起的静电荷屏蔽进行建模
Matthew R Warren,Ambika G Bajpayee
Matthew R Warren
Background: Positively charged drug carriers are rapidly emerging as a viable solution for long-standing challenges in delivery to dense, avascular, negatively charged tissues. These cationic carriers have demonstrated es...
Alistair V W Nunn,Geoffrey W Guy,Jimmy D Bell
Alistair V W Nunn
The consensus on the origins of life is that it involved organization of prebiotic chemicals according to the underlying principles of thermodynamics to dissipate energy derived from photochemical and/or geochemical sources. Leading theorie...
Determination of the Effects of Transcutaneous Auricular Vagus Nerve Stimulation on the Heart Rate Variability Using a Machine Learning Pipeline [0.03%]
基于机器学习流程的经皮耳迷走神经刺激对心率变异性影响的研究
Anna Tarasenko,Stefano Guazzotti,Thomas Minot et al.
Anna Tarasenko et al.
Background: We are all aware of day-to-day healthy stress, but, when sustained for long periods, stress is believed to lead to serious physical and mental health issues. ...
Enhancement of Bone Regeneration Through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation [0.03%]
一种新型的利用逆压电效应施加力学刺激促进骨再生的方法
Amber Carter,Kristen Popowski,Ke Cheng et al.
Amber Carter et al.
Serious bone injuries have devastating effects on the lives of patients including limiting working ability and high cost. Orthopedic implants can aid in healing injuries to an extent that exceeds the natural regenerative capabilities of bon...
Lung Ablation with Irreversible Electroporation Promotes Immune Cell Infiltration by Sparing Extracellular Matrix Proteins and Vasculature: Implications for Immunotherapy [0.03%]
通过不可逆电穿孔肺消融促进免疫细胞浸润，通过保存细胞外基质蛋白和血管：对免疫治疗的影响
Masashi Fujimori,Yasushi Kimura,Eisuke Ueshima et al.
Masashi Fujimori et al.
Background: This study investigated the sparing of the extracellular matrix (ECM) and blood vessels at the site of lung irreversible electroporation (IRE), and its impact on postablation T cell and macrophage populations. Materials and Meth...
Optical Estimation of Absolute Membrane Potential Using One- and Two-Photon Fluorescence Lifetime Imaging Microscopy [0.03%]
利用一和二维荧光寿命成像显微镜对绝对膜电位进行光学估计
Julia R Lazzari-Dean,Evan W Miller
Julia R Lazzari-Dean
Background: Membrane potential (V mem) exerts physiological influence across a wide range of time and space scales. To study V mem in these diverse contexts, it is essential to accurately record absolute values of V mem, rather than solely ...
Myocardial Edema Revisited in a New Paradigm of Cardiac Electrical Microcurrent Application in Heart Failure [0.03%]
心力衰竭中心肌水肿在心脏电微电流应用新机制中的再认识
Jesus Eduardo Rame,Johannes Müller
Jesus Eduardo Rame
Undisturbed bioelectricity is a prerequisite for normal organ function. This is especially true for organs with high electrical activity such as the heart and the nervous system. Under clinical conditions, however, this can hardly be determ...
Finding the Spark [0.03%]
寻找火花
Joel M Kralj
Joel M Kralj
It began, as with many good things, at a happy hour. Adam Cohen, a young assistant professor asked whether rhodopsins could be used to optically sense voltage. In the heady days of 2009, channel rhodopsin had just been unveiled as a voltage...