World Opioid and Substance Use Epidemic: A Latin American Perspective [0.03%]
全球阿片类药和物质滥用流行现状:拉丁美洲视角
Saul Francisco Pacurucu-Castillo,José Marcelo Ordóñez-Mancheno,Adrián Hernández-Cruz et al.
Saul Francisco Pacurucu-Castillo et al.
The opioid crisis is a growing social and public health phenomenon, particularly in developed countries such as the United States. Since the 1990s, this crisis has shown a variety of causal processes and consequences and has affected qualit...
Clinical Features of Psychotic Disorders: Comparing Categorical and Dimensional Models [0.03%]
精神分裂症障碍的临床特征:类别模型与维度模型的比较研究
Caitlin Ravichandran,Dost Ongur,Bruce M Cohen
Caitlin Ravichandran
Objective: Despite research demonstrating the value of dimensional approaches, standard systems for classifying psychotic disorders rely primarily on categorization of patients into distinct diagnoses. We present the firs...
Shortened Positive and Negative Symptom Scale as an Alternate Clinical Endpoint for Acute Schizophrenia Trials: Analysis from the US Food & Drug Administration [0.03%]
美国食品药品管理局分析:作为急性精神分裂症临床试验的替代临床终点的简化阳性阴性症状量表
Mathangi Gopalakrishnan,Tiffany Farchione,Mitchell Mathis et al.
Mathangi Gopalakrishnan et al.
Objective: To evaluate the performance of the individual Positive and Negative Symptom Scale (PANSS) items, and to assess the feasibility of using a shortened version of the PANSS as an alternative regulatory endpoint for...
Mental Health-Related Emergency Department Visits Among Children During The Early COVID-19 Pandemic [0.03%]
2019冠状病毒病大流行初期美国儿童因心理健康相关问题到急诊就诊情况
Juliet Beni Edgcomb,Nicole M Benson,Chi-Hong Tseng et al.
Juliet Beni Edgcomb et al.
Objective: To measure univariate and covariate-adjusted trends in children's mental health-related emergency department (MH-ED) use across geographically diverse areas of the U.S. during the first wave of the Coronavirus-...
CRF serum levels differentiate PTSD from healthy controls and TBI in military veterans [0.03%]
CRF的血清水平可将PTSD与健康对照组及创伤性脑损伤区分开来——对退伍军人的研究
Jaime Ramos-Cejudo,Afia Genfi,Duna Abu-Amara et al.
Jaime Ramos-Cejudo et al.
Background and objective: Posttraumatic stress disorder (PTSD) is a serious and frequently debilitating psychiatric condition that can occur in people who have experienced traumatic stessors, such as war, violence, sexual...
J Allan Hobson,Jarrod A Gott,Karl J Friston
J Allan Hobson
Objective: This article offers a philosophical thesis for psychiatric disorders that rests upon some simple truths about the mind and brain. Specifically, it asks whether the dual aspect monism-that emerges from sleep res...
Strategies to aid self-isolation and quarantine for individuals with severe and persistent mental illness during the COVID-19 pandemic: A systematic review [0.03%]
新冠疫情期间协助严重且长期精神疾病患者进行隔离和自我隔离的策略:系统综述
Anees Bahji,Paxton Bach,Marlon Danilewitz et al.
Anees Bahji et al.
Background: Individuals with severe and persistent mental illness (SPMI) have a higher risk of contracting COVID-19 than individuals without SPMI. In combination with physical distancing, hygiene protocols, and vaccines, ...
Celestina Barbosa-Leiker,Aimee N C Campbell,R Kathryn McHugh et al.
Celestina Barbosa-Leiker et al.
Objective: The opioid epidemic continues to evolve and impact all groups of people. Moreover, there are concerning trends among women. The aim of this article is to provide a review of opioid use disorder in women and the...
Psychotic-Like Experiences in Adolescence Occurring in Combination or Isolation: Associations with Schizophrenia Risk Factors [0.03%]
青春期出现的精神病样体验:单独发生还是组合发生与精神分裂症危险因素的联系
Alastair G Cardno,Saskia Selzam,Daniel Freeman et al.
Alastair G Cardno et al.
Objectives: Individual adolescent psychotic-like experiences (PLEs) are associated with schizophrenia risk factors. As DSM-5 schizophrenia requires the co-occurrence of at least two psychotic symptoms, we investigated whe...
Esha Chebolu,Melanie L Schwandt,Vijay A Ramchandani et al.
Esha Chebolu et al.
Objective: Interindividual variation in responses to alcohol is substantial, posing challenges for medical management and for understanding the biological underpinnings of alcohol use disorders (AUD). It is important to u...