Bethany Percha
Bethany Percha
Electronic health records (EHRs) are becoming a vital source of data for healthcare quality improvement, research, and operations. However, much of the most valuable information contained in EHRs remains buried in unstructured text. The fie...
Jingqi Chen,Guiying Dong,Liting Song et al.
Jingqi Chen et al.
The accumulation of vast amounts of multimodal data for the human brain, in both normal and disease conditions, has provided unprecedented opportunities for understanding why and how brain disorders arise. Compared with traditional analyses...
Metatranscriptomics for the Human Microbiome and Microbial Community Functional Profiling [0.03%]
人类微生物组和微生物群功能谱系的元转录组学
Yancong Zhang,Kelsey N Thompson,Tobyn Branck et al.
Yancong Zhang et al.
Shotgun metatranscriptomics (MTX) is an increasingly practical way to survey microbial community gene function and regulation at scale. This review begins by summarizing the motivations for community transcriptomics and the history of the f...
Siobhan Cleary,Cathal Seoighe
Siobhan Cleary
Diploidy has profound implications for population genetics and susceptibility to genetic diseases. Although two copies are present for most genes in the human genome, they are not necessarily both active or active at the same level in a giv...
Angela Oliveira Pisco,Bruno Tojo,Aaron McGeever
Angela Oliveira Pisco
Cell atlases are essential companions to the genome as they elucidate how genes are used in a cell type-specific manner or how the usage of genes changes over the lifetime of an organism. This review explores recent advances in whole-organi...
Lee Call,Stephen Nayfach,Nikos C Kyrpides
Lee Call
Viruses are the most abundant biological entity on Earth, infect cellular organisms from all domains of life, and are central players in the global biosphere. Over the last century, the discovery and characterization of viruses have progres...
George-John Nychas,Emma Sims,Panagiotis Tsakanikas et al.
George-John Nychas et al.
Food safety is one of the main challenges of the agri-food industry that is expected to be addressed in the current environment of tremendous technological progress, where consumers' lifestyles and preferences are in a constant state of flu...
Xinyue Zhang,Peng Gao,Michael P Snyder
Xinyue Zhang
Human health is regulated by complex interactions among the genome, the microbiome, and the environment. While extensive research has been conducted on the human genome and microbiome, little is known about the human exposome. The exposome ...
Artificial Intelligence in Action: Addressing the COVID-19 Pandemic with Natural Language Processing [0.03%]
人工智能应对新冠疫情：自然语言处理的作用
Qingyu Chen,Robert Leaman,Alexis Allot et al.
Qingyu Chen et al.
The COVID-19 (coronavirus disease 2019) pandemic has had a significant impact on society, both because of the serious health effects of COVID-19 and because of public health measures implemented to slow its spread. Many of these difficultie...
Tianming Zhou,Ruochi Zhang,Jian Ma
Tianming Zhou
The spatial organization of the genome in the cell nucleus is pivotal to cell function. However, how the 3D genome organization and its dynamics influence cellular phenotypes remains poorly understood. The very recent development of single-...