Altered DNA Methyltransferase Expression in Pulmonary Large-Cell Neuroendocrine Carcinoma: Pilot Experimental Data Targeted DNMT1, DNMT3A, and DNMT3B [0.03%]
肺巨细胞神经内分泌癌中DNA甲基转移酶表达改变:针对DNMT1、DNMT3A和DNMT3B的初步实验数据
Adam Put,Katerina Smesny Trtkova,Marcel Mittak et al.
Adam Put et al.
Introduction: Large cell neuroendocrine carcinoma (LCNEC) is a subtype of non-small-cell lung carcinoma with poorly understood methylation characteristics, including the activity of DNA methyltransferases. Despite the piv...
The Aberrant Activation of NLRP3 in Microsatellites Stability Colon Cancer Promotes M2 Macrophage Polarization Based on the TCGA Database and Tissue Microarray Analysis [0.03%]
基于TCGA数据库和组织微阵列分析的小卫星稳定性结直肠癌中NLRP3异常活化促进M2型巨噬细胞极化
Li Lu,Menglin Wu,Xunzhen Jiang et al.
Li Lu et al.
Background: Microsatellites stability (MSS) colon cancer patients exhibit a significant suppressive immune status, and the functional status of tumor NLRP3 immunosomes plays an important role in regulating the tumor immun...
Identification of BRAF V600E Mutation in Cerebrospinal Fluid Aids in Diagnosing Leptomeningeal Carcinomatosis Arising From Pleomorphic Xanthoastrocytoma: A Case Report [0.03%]
脑脊液中BRAF V600E突变检测在弥漫性天幕脑膜瘤诊断中的应用:一例多形性黄色星形细胞瘤病例报告
Randy S DAmico,Patricia Avancena,Alon Kashanian et al.
Randy S DAmico et al.
Background: Pleomorphic xanthoastrocytomas (PXAs) are rare primary central nervous system (CNS) tumors that appear heterogeneous on imaging and histology and typically cause headaches or seizures on initial presentation. ...
An In-Depth Evaluation of CD15 Expression in Thyroid Carcinoma: A Comprehensive Systematic Review [0.03%]
甲状腺癌中CD15表达的深度评价:全面系统性回顾分析
Amir Ebrahimzadeh Pasha,Amirhossein Ehsani,Sara Ashtari et al.
Amir Ebrahimzadeh Pasha et al.
Background: Cluster of differentiation 15 (CD15) is a carbohydrate epitope implicated in cell adhesion, migration, and tumor progression. It is variably expressed in thyroid carcinoma (TC) subtypes. However, its diagnosti...
The Effect of Interferon Type I Adjuvant Therapy on the Lifespan and Complications of Glioma Patients Undergoing Chemotherapy: A Systematic Review and Meta-Analysis [0.03%]
I型干扰素辅助治疗对胶质瘤化疗患者生存期和并发症的影响:系统评价和 meta 分析
Nima Goudarzi,Abolfazl Sam Daliri,Arshia Harati et al.
Nima Goudarzi et al.
Background: The malignant glioma, as the most common and aggressive primary brain and spinal cord neoplasm, has shown limited responsiveness to available treatments, including tumor dissection, radiation, and chemotherapy...
Meta-Analysis
Cancer reports (Hoboken, N.J.). 2026 Mar;9(3):e70507. DOI:10.1002/cnr2.70507 2026
Ten-Year Outcome of a Patient With Concurrent Pelvic Myeloid Sarcoma and Underlying Chronic Myeloid Leukaemia in Chronic Phase: A Case Report and Literature Review [0.03%]
慢性粒细胞白血病慢性期合并盆腔粒细胞性肉瘤的10年预后及相关文献述评——1例报告
Kar Ying Yong,Soo How Lim,Lee Gong Lau et al.
Kar Ying Yong et al.
Background: Myeloid sarcoma is a rare solid tumour of immature myeloid precursors occurring in an extramedullary site. It often presents significant diagnostic and therapeutic challenges to clinical haematologists. ...
Cytotoxicity Potency of Cannabinoids Is by Serum Supplementation: Implications for In Vitro Cancer Studies [0.03%]
cannabinoids的细胞毒性活性受血清补充的影响:对体外癌症研究的意义
Sanele Priscillia Mathibela,Maphuti Tebogo Lebelo,Vanessa Steenkamp
Sanele Priscillia Mathibela
Background: Fetal calf serum (FCS) is a key supplement in cell culture, providing nutrients, and growth factors that support cancer cell proliferation. Studies suggest that compound cytotoxicity profiles in vitro vary dep...
Comparative Liquid Biopsy Testing for KRAS Mutations From Plasma Cell-Free DNA (cfDNA) and Extracellular Vesicles in Lung Adenocarcinoma [0.03%]
比较分析肺癌肺腺癌患者血浆游离DNA和外泌体中KRAS突变的液体活检检测结果
Caeli J Zahra,Tian Mun Chee,Edward K H Stephens et al.
Caeli J Zahra et al.
Background: Liquid biopsy has emerged as a promising, minimally invasive tool to detect cancer biomarkers. Extracellular vesicles (EVs) are secreted into biofluids to transport cargo such as DNA and are a potential biosou...
Comparative Study
Cancer reports (Hoboken, N.J.). 2026 Mar;9(3):e70517. DOI:10.1002/cnr2.70517 2026
Expanding the Anatomical Distribution of PRRX1::KMT2D Fusion Mesenchymal Neoplasms: A Rare Mediastinal Case Report [0.03%]
PRRX1::KMT2D融合间充质瘤的解剖分布扩展:一例罕见纵隔肿瘤的病例报告
Weixiang Zhong,Yu Deng,Ke Sun
Weixiang Zhong
Background: PRRX1-rearranged mesenchymal neoplasms are rare soft tissue tumors with a predilection for the superficial subcutaneous tissue. The PRRX1::KMT2D fusion variant is exceptionally rare, with only three previously...
Complementary and Alternative Medicine in Oncology: A Concise Review of Utilization, Evidence, and Integration Challenges [0.03%]
肿瘤学中的补充和替代医学:利用、证据及整合挑战的简明综述
Danica Schöneseiffen,Matthias B Stope
Danica Schöneseiffen
Background: Complementary and alternative medicine (CAM) is widely used by cancer patients and increasingly shapes oncological care worldwide. This narrative review examines current evidence on utilization patterns, theor...