Efficacy and Safety of Different Neoadjuvant Treatment Regimens in Locally Advanced Squamous Head and Neck Cancer [0.03%]
不同新辅助治疗方案在局部晚期头颈部鳞癌中的有效性和安全性研究
Ya-Ting Ding,Bin-Bin Fang,Lian-Bing Zhu et al.
Ya-Ting Ding et al.
Background: Head and neck squamous cell carcinoma (HNSCC), which constitutes approximately 90% of all head and neck cancers, represents a significant global health burden. A concerning trend is the rising incidence, parti...
Outcomes and Management of Dermatologic Toxicity Following Enfortumab Vedotin Rechallenge in Patients With Metastatic Urothelial Carcinoma: A Retrospective Single-Center Study [0.03%]
恩fortumab vedotin再挑战治疗转移性尿路上皮癌后患者的临床结局及皮肤毒性管理：一项基于单中心的回顾性研究
Takashi Kawahara,Yoshiyuki Nagumo,Akane Yamaguchi et al.
Takashi Kawahara et al.
Background: Enfortumab vedotin (EV) has demonstrated clinical benefits as a third-line monotherapy after chemotherapy and immune checkpoint inhibitors and is currently established, in combination with pembrolizumab, as a ...
Observational Study
Cancer reports (Hoboken, N.J.). 2026 Jan;9(1):e70466. DOI:10.1002/cnr2.70466 2026
Clinical Course and Risk Factors of Lenvatinib-Related Hypothyroidism in Hepatocellular Carcinoma: A Retrospective Cohort Study [0.03%]
仑伐替尼相关性甲减的临床经过及危险因素——一项回顾队列研究
Chihiro Shiraishi,Hideo Kato,Yuki Asai et al.
Chihiro Shiraishi et al.
Background: Lenvatinib-related hypothyroidism occurs in 16%-22% of patients with hepatocellular carcinoma and may affect treatment management. Previous studies have reported elevated serum thyroid stimulating hormone (TSH...
Significance and Correlation Analysis of Folate Receptor-Positive Circulating Tumor Cells (FR + CTC) in Colorectal Cancer Patients [0.03%]
结直肠癌患者叶酸受体阳性循环肿瘤细胞的临床意义及关联分析
Renwang Hu,Aofeng Lan,Dan Li et al.
Renwang Hu et al.
Background: To investigate the significance of detecting folate receptor-positive circulating tumor cells (FR + CTC) in colorectal cancer patients and to analyze their correlation with the expression of conventional tumor...
Transmembrane Protein TMEM59L Modulates 5-FU Resistance via PTPRN-Mediated DNA Damage Repair in Colorectal Cancer [0.03%]
跨膜蛋白TMEM59L通过PTPRN介导的DNA损伤修复调节结直肠癌对5-氟尿嘧啶耐药性
Wenzhi Jin,Qiang Ma,Zenghui Ma et al.
Wenzhi Jin et al.
Background: Chemotherapy resistance in colorectal cancer (CRC) is often mediated by enhanced DNA damage repair (DDR). Transmembrane protein TMEM59L is implicated in cancer progression, but its role in CRC chemoresistance ...
Challenges and Limitations of Sequential MET-TKI Therapy in METex14- Positive NSCLC With a Focus on Non-ILD Toxicities: A Case Report [0.03%]
MET exon14跳突阳性非小细胞肺癌序贯MET-TKI治疗的挑战和局限性：重点关注非间质性肺炎毒性（个案报告）
Akina Nigi,Toshikazu Kumasa,Keisuke Iwamoto et al.
Akina Nigi et al.
Background: Nonsmall cell lung cancer (NSCLC) with mesenchymal-epithelial transition exon 14 skipping mutation (METex14) represents a distinct molecular subtype with limited therapeutic options. Selective MET tyrosine kin...
Adenoid Cystic Carcinoma of the Breast: Clinicopathological Features, Therapy Strategy, and Prognosis [0.03%]
乳腺腺样囊性癌的临床病理特征、治疗策略及预后研究
Lan Chen,Shuang Dai,Xi Yan
Lan Chen
Background: Adenoid cystic carcinoma (ACC) of the breast is a special subtype of breast cancer. Aims: This study aimed to systematicall...
Breast Health Training Program for Traditional Healers: A Pathway to Early Breast Cancer Detection in Tanzania [0.03%]
坦桑尼亚传统医术乳腺健康培训项目：通往早期乳腺癌检测的道路
Autumn Beavers,Elizabeth F Msoka,Irene Masue et al.
Autumn Beavers et al.
Background: In sub-Saharan Africa, traditional healers often serve as primary healthcare providers and are the first point of contact for patients. Given this, they are uniquely positioned to aid in early breast cancer de...
How Do Patient Demographics and Socioeconomic Disadvantage Impact Clinical Presentation, Surgical Outcomes, and Survival for Upper Extremity Soft Tissue Sarcoma? [0.03%]
患者人口统计学特征和经济社会劣势对上肢软组织肉瘤临床表现、手术结局及生存率的影响如何？
Nicole J Newman-Hung,Kameel Khabaz,Michaela Juels et al.
Nicole J Newman-Hung et al.
Background: Soft tissue sarcomas (STS) of the upper extremity (UE) are uncommon and may require complex surgical management. Socioeconomic disadvantage, race/ethnicity, sex, and marital status may influence presentation, ...
Frailty in Patients With Hematologic Malignancies and Patients Undergoing Hematopoietic Stem Cell Transplantation: A Systematic Review [0.03%]
血液系统恶性肿瘤患者和接受造血干细胞移植患者的衰弱状态：一项系统性回顾
Marit Bakken,Marie Roko Kallager,Marie Hamilton Larsen et al.
Marit Bakken et al.
Background: Hematopoietic stem cell transplantation (HSCT) is associated with significant morbidity and mortality. Frailty further increases these risks in recipients of HSCT. This systematic review analyzes the extent of...