Can health inequalities in sickle cell disease be addressed through novel therapies? [0.03%]
新型疗法能否解决镰状细胞病的健康不平等问题?
Stephen P Hibbs,Richard J Buka,Mary Shaniqua et al.
Stephen P Hibbs et al.
Circulating tumor-associated and neoantigen-specific endogenous T cells in children treated for B-acute lymphoblastic leukemia [0.03%]
儿童B细胞急性淋巴细胞白血病治疗过程中肿瘤相关及新抗原特异性内源性T细胞的循环作用
Eliane Huwiler,Anne-Christine Thierry,Justine Michaux et al.
Eliane Huwiler et al.
A spheroid model that recapitulates the protective role of the lymph node microenvironment and serves as a platform for drug testing in chronic lymphocytic leukemia [0.03%]
一种球形模型可再现淋巴结微环境的保护作用并可用于慢性淋巴细胞白血病药物筛选测试
Elisa Lenti,Edoardo Visentin,Engin Bojnik et al.
Elisa Lenti et al.
Chronic lymphocytic leukemia (CLL) B cells are characterized by a propensity to undergo rapid apoptosis when cultured in vitro, underscoring the importance of the tissue microenvironment for disease survival. One of the major limitations in...
Prognostic impact and clinical value of low levels of flow cytometric MRD at the end of induction in childhood B-lineage acute lymphoblastic leukemia: Results of study ALL-MB 2015 [0.03%]
儿童B淋巴细胞急性淋巴细胞白血病中诱导末期流式细胞术微小残留病低水平的预后影响及临床价值:ALL-MB 2015研究结果
Alexander Popov,Guenter Henze,Julia Roumiantseva et al.
Alexander Popov et al.
CHIC: A machine learning framework for inferring the presence of high-risk clonal hematopoiesis using complete blood count data from 431,531 UK Biobank participants [0.03%]
利用英国生物银行431,531名参与者的数据基于完整血液计数数据推断克隆型造血现象的机器学习框架CHIC
William G Dunn,Isabella Withnell,Muxin Gu et al.
William G Dunn et al.
Gianpietro Semenzato,Antonella Teramo,Gregorio Barilà et al.
Gianpietro Semenzato et al.
NK-large granular lymphocyte leukemia (NK-LGLL) is a lymphoid malignancy driven by constitutive activation of cellular pathways and chronic inflammation, underscoring the central role of the microenvironment in the disease's pathogenesis. P...
Fetal-hemoglobin-expressing red blood cells ("F cells") consist of three distinct types as revealed by single-cell transcriptomic analysis of circulating reticulocytes [0.03%]
单细胞转录组分析揭示出的胎儿血红蛋白表达红细胞(“F 细胞”)包含三种不同的类型
Helen Rooks,Cecilia Ng,Spyros Oikonomopoulos et al.
Helen Rooks et al.
Adama Ladu,Stephen P Hibbs
Adama Ladu
Editorial
HemaSphere. 2025 Jun 17;9(6):e70157. DOI:10.1002/hem3.70157 2025
Comparable outcomes for pediatric acute lymphoblastic leukemia patients receiving conditioning with total body irradiation or chemotherapy: A nationwide, Korean registry-based study [0.03%]
基于韩国全国注册资料的儿童急性淋巴细胞白血病患者接受全身照射或化疗预处理的结局比较研究
Kyung Taek Hong,Jung Yoon Choi,Hyery Kim et al.
Kyung Taek Hong et al.
Acute lymphoblastic leukemia (ALL) is the predominant malignancy in pediatric patients, and allogeneic hematopoietic stem cell transplantation (HSCT) plays a critical role in high-risk cases. However, real-world nationwide data comparing th...
Prognostic significance of PET/CT for CAR T cell therapy in relapsed/refractory multiple myeloma [0.03%]
PET/CT对复发难治多发性骨髓瘤CAR-T治疗预后价值评估
Patrick Born,David Fandrei,Song Yau Wang et al.
Patrick Born et al.
PET/CT plays an important role in staging of multiple myeloma (MM) and detecting extramedullary disease (EMD); however, its role in patients treated with commercially available CAR T cell therapies is unclear. We evaluated 61 patients treat...