Hepatic steatosis as measured by the computed attenuation parameter predicts fibrosis in long-term methotrexate use [0.03%]
长期使用甲氨蝶呤肝脂肪变性预测纤维化指标的参数模型计算评估结果显示肝脏衰弱程度较高
Marcel Tomaszewski,Monica Dahiya,Seyed Amir Mohajerani et al.
Marcel Tomaszewski et al.
Introduction: To determine predictors of hepatic steatosis by the computed attenuation parameter (CAP) and fibrosis via transient elastography (TE) in persons on methotrexate (MTX) therapy with rheumatologic and dermatolo...
Comparison of public and private payments for direct-acting antivirals (DAAs) across Canada [0.03%]
加拿大各省直接抗病毒药物(DAAs)的公费和自费比较研究
Ahmad Shakeri,Kaleen N Hayes,Tara Gomes et al.
Ahmad Shakeri et al.
Cost-effectiveness of obeticholic acid for the treatment of non-alcoholic steatohepatitis: An early economic evaluation [0.03%]
奥贝胆酸治疗非酒精性脂肪肝病的经济效果分析：一项早期经济学评价
Chanh-Phong Tran,John J Kim,Jordan J Feld et al.
Chanh-Phong Tran et al.
Background: Currently, there are no pharmacological options available for the treatment of non-alcoholic steatohepatitis (NASH). In the 18-month interim analysis of an ongoing randomized, placebo-controlled phase 3 trial ...
Bears, beets, rifaximin [0.03%]
熊，甜菜，利福昔明
Peter L Wang,Jennifer A Flemming
Peter L Wang
A real-world experience of SARS-CoV-2 infection in a tertiary referral centre of Montréal: Unexpected low prevalence and low mortality [0.03%]
蒙特利尔三级转诊中心SARS-CoV-2感染的真实世界经验：意外低流行率和低死亡率
Isaac Ruiz,Geneviève Huard,Claire Fournier et al.
Isaac Ruiz et al.
Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with chronic liver disease (CLD) and liver transplant (LT) recipients remains a concern. The aim of this study w...
Yaqeen Abduallah,Safaa Azzouz,Kelita Singh et al.
Yaqeen Abduallah et al.
A sinus of Valsalva aneurysm (SOVA) is a rare cardiac defect in which the aortic root area between the aortic annulus and the sinotubular junction is dilated. We present a case of acute liver failure (ALF) in a 21-year-old man secondary to ...
Characterizing risk behaviour and reinfection rates for successful programs to engage core transmitters in HCV elimination (C-RESPECT) [0.03%]
丙肝消除项目中识别高风险人群及再感染率（C-RESPECT）
Brian Conway,Dan Smyth,Réjean Thomas et al.
Brian Conway et al.
Background: Development of robust treatment programs among core transmitters (CT) of hepatitis C virus (HCV) are needed, including strategies to address reinfection risk. The aim of this study was to describe the effectiv...
Palbociclib-induced severe hepatitis: A case study and literature review [0.03%]
帕博西尼致重度肝损害的病例分析及文献复习
Jessie Jean Hyppolite,Nir Hilzenrat
Jessie Jean Hyppolite
Palbociclib is a selective and reversible CDK4/6 inhibitor approved for patients presenting with HR+ HER2- locally advanced or metastatic breast cancer. Its adverse effect (AE) is mainly reported on the occurrence of leukopenia and fatigue....
A national paucity of hepatologists: An unprecedented opportunity for interdisciplinary collaboration [0.03%]
肝病学家短缺催生跨学科协作前所未有的机遇
Sydney McLean,Eric M Yoshida,Sanjeev Sirpal et al.
Sydney McLean et al.
Survival and development of health conditions after iron depletion therapy in C282Y-linked hemochromatosis patients [0.03%]
铁耗尽治疗C282Y遗传性血色病患者的健康状况的生存和发展分析
Paul C Adams,Lucie Richard,Matthew Weir et al.
Paul C Adams et al.
Background: We report long-term survival and development of selected health conditions in Ontario-based referred and screened C282Y homozygotes for hemochromatosis treated by phlebotomy compared with an untreated control ...