The Presence of Lactobacillus spp. and its Effect on the Occurrence of Other Microorganisms in the Reproductive Tract of Polish Women [0.03%]
乳酸菌的存在及其对波兰女性生殖道其他微生物发生率的影响
Aneta Kiecka,Katarzyna Rak,Joanna Białecka et al.
Aneta Kiecka et al.
Disorders of the vaginal microbiota can lead to many complications and affect fertility. This study evaluates the role of Lactobacillus in the vagina and its impact on the incidence of colonization by pathogenic microorganisms, analyzing th...
Cloning Cellulase Genes from Victoria Falls Rainforest Decaying Logs Metagenome [0.03%]
从维多利亚瀑布雨林腐木宏基因组克隆纤维素酶基因
Makhosazana Nyathi,Zephaniah Dhlamini,Thembekile Ncube
Makhosazana Nyathi
The Victoria Falls rainforest is a protected site whose forest floors harbor a host of cellulolytic microorganisms involved in biomass degradation. This study collected decaying logs and soil from the rainforest for bioprospecting cellulase...
Halogenated Secondary Metabolites from Higher Plants: Potent Drug Candidates for Chikungunya Using in silico Approaches [0.03%]
高等植物卤化次生代谢产物：利用计算方法鉴定夏克热病毒候选药物
Sushil Kumar,Nidhi Joshi,Gourav Choudhir et al.
Sushil Kumar et al.
Chikungunya virus (CHIKV) causes a debilitating fever and joint pain, with no specific antiviral treatment available. Halogenated secondary metabolites from plants are a promising new class of drug candidates against chikungunya, with uniqu...
Establishment of a Nucleic Acid Detection Method for Norovirus GII.2 Genotype Based on RT-RPA and CRISPR/Cas12a-LFS [0.03%]
基于RT-RPA和CRISPR/Cas12a-LFD的诺如病毒GII.2型核酸检测方法的建立
Ting Wang,Hao Zeng,Jie Kang et al.
Ting Wang et al.
To establish a rapid detection method for norovirus GII.2 genotype, this study employed reverse transcription recombinase polymerase amplification (RT-RPA) combined with CRISPR/Cas12a and lateral flow strip (RT-RPA-Cas12a-LFS). Here, the ge...
Biological Characteristics of the Mycelium and Optimization of the Culture Medium for Phallus dongsun [0.03%]
东松环裙菌菌丝体生物学特性及培养基优化
Chao Kang,Xuan Zheng,Wankun Wang et al.
Chao Kang et al.
This study aimed to elucidate the influence of various culture medium components, including carbon sources, nitrogen sources, inorganic salts, suspension agents, and temperature, on the mycelial growth characteristics of Phallus dongsun. Em...
Guanylate-Binding Protein 1 (GBP1) Enhances IFN-α Mediated Antiviral Activity against Hepatitis B Virus Infection [0.03%]
鸟苷酸结合蛋白GBP1通过促进I型干扰素抗病毒作用抑制乙肝病毒感染
Yadi Li,Haiying Luo,Xiaoxia Hu et al.
Yadi Li et al.
Interferon-alpha (IFN-α) is a first-line drug for treating chronic hepatitis B (CHB). Guanylate-binding protein 1 (GBP1) is one of the interferon-stimulating factors, which participates in the innate immunity of the host and plays an antiv...
Negative Pressure Level and Effects on Bacterial Growth Kinetics in an in vitro Wound Model [0.03%]
负压水平及对体外伤口模型中细菌生长动力学的影响研究
Adam Bobkiewicz,Wojciech Francuzik,Amy Martinkosky et al.
Adam Bobkiewicz et al.
Negative Pressure Wound Therapy (NPWT) has been widely adopted in wound healing strategies due to its multimodal mechanism of action. While NPWT's positive impression on wound healing is well-established, its effect on bacterial load reduct...
Potential Usefulness of IgA for the Early Detection of SARS-CoV-2 Infection: Comparison With IgM [0.03%]
IgA在SARS-CoV-2感染早期检测中的潜在应用价值：与IgM的比较
Pei Wang
Pei Wang
Serological testing can be a powerful complementary approach to achieve timely diagnosis of severe acute respiratory coronavirus 2 (SARS-CoV-2) infection, along with nucleic acid detection. Immunoglobulin (Ig) A antibodies are less frequent...
Analysis of the Class 1 Integrons, Carbapenemase Genes and Biofilm Formation Genes Occurrence in Acinetobacter baumannii Clinical Isolates [0.03%]
肺炎克雷伯菌耐碳青霉烯类抗生素分子机制及毒力研究
Yu Xiu,Yueru Dai,Shasha Yin et al.
Yu Xiu et al.
Acinetobacter baumannii is a non-fermentative Gram-negative bacterium that can cause nosocomial infections in critically ill patients. Carbapenem-resistant A. baumannii (CRAB) has spread rapidly in clinical settings and has become a key con...
Epidemiological Characteristics of Shiga Toxin-Producing Escherichia coli Responsible for Infections in the Polish Pediatric Population [0.03%]
波兰儿童产志贺毒素的大肠杆菌感染的流行病学特征
Dominika Seliga-Gąsior,Beata Sokól-Leszczyñska,Jolanta Krzysztoñ-Russjan et al.
Dominika Seliga-Gąsior et al.
Shiga toxin-producing Escherichia coli (STEC) are zoonotic pathogens causing hemorrhagic colitis and hemolytic uremic syndrome (HUS) in children and the elderly. Stool samples were collected from 180 children hospitalized in five pediatric ...