A Rare STRN-ALK Fusion in Lung Adenocarcinoma Identified Using Next-Generation Sequencing-Based Circulating Tumor DNA Profiling Exhibits Excellent Response to Crizotinib [0.03%]
基于下一代测序的循环肿瘤DNA谱分析鉴定出罕见的STRN-ALK重排在肺腺癌中对克唑替尼表现出色响应
Yan Yang,Shu-Kui Qin,Jian Zhu et al.
Yan Yang et al.
The ALK gene fusion has been identified as a new driver gene in non-small cell lung cancer (NSCLC). It includes the EML4-ALK rearrangement as a recurring event that renders the tumor sensitive to ALK tyrosine kinase inhibitor crizotinib. In...
Automated Diabetes Case Identification Using Electronic Health Record Data at a Tertiary Care Facility [0.03%]
三级医疗保健机构电子健康记录数据的糖尿病病例自动化识别
Sudhi G Upadhyaya,Dennis H Murphree Jr,Che G Ngufor et al.
Sudhi G Upadhyaya et al.
Objective: To develop and validate a phenotyping algorithm for the identification of patients with type 1 and type 2 diabetes mellitus (DM) preoperatively using routinely available clinical data from electronic health rec...
Effect of Antimicrobial Stewardship Program Guidance on the Management of Uncomplicated Skin and Soft Tissue Infections in Hospitalized Adults [0.03%]
抗菌药物管理方案在住院成人单纯性皮肤和软组织感染治疗中的作用
Thomas L Walsh,Derek N Bremmer,Matthew A Moffa et al.
Thomas L Walsh et al.
Objective: To assess the effect of an antimicrobial stewardship program (ASP)-bundled initiative on the appropriate use of antibiotics for uncomplicated skin and soft tissue infections (uSSTIs) at 2 academic medical cente...
Pretravel Health Preparation of International Travelers: Results From the Boston Area Travel Medicine Network [0.03%]
国际旅行者的出行前健康准备：来自波士顿地区旅行医学网络的结果
Davidson H Hamer,William B MacLeod,Lin H Chen et al.
Davidson H Hamer et al.
Objective: To inform future interventions for advising travelers. Patients and methods: We prospectively collected data on travelers se...
Combined Association of Cardiorespiratory Fitness and Body Fatness With Cardiometabolic Risk Factors in Older Norwegian Adults: The Generation 100 Study [0.03%]
体能和体脂与老年人心血管代谢危险因素联合关联性研究——Generation 100 研究报告
Silvana B Sandbakk,Javaid Nauman,Carl J Lavie et al.
Silvana B Sandbakk et al.
Objective: To investigate the independent and combined associations of fitness and fatness with cardiometabolic risk factors in older Norwegian women and men. ...
Normalization of Testosterone Levels After Testosterone Replacement Therapy Is Not Associated With Reduced Myocardial Infarction in Smokers [0.03%]
睾酮替代治疗后睾酮水平的正常化与吸烟者心肌梗死减少无关
Olurinde A Oni,Rishi Sharma,Guoqing Chen et al.
Olurinde A Oni et al.
Objective: To examine the effect of cigarette smoking (CS) status and total testosterone (TT) levels after testosterone replacement therapy (TRT) on all-cause mortality, myocardial infarction (MI), and stroke in male smok...
Experience and Outcomes at a Specialized Clostridium difficile Clinical Practice [0.03%]
专治艰难梭菌感染的专科门诊的经验和预后分析
Raseen Tariq,Renee M Weatherly,Patricia P Kammer et al.
Raseen Tariq et al.
Objective: To report our experience with and outcomes among patients referred to a specialized Clostridium difficile clinical practice. Patients and metho...
Acute Alcoholic Hepatitis: Natural History and Predictors of Mortality Using a Multicenter Prospective Study [0.03%]
急性酒精性肝炎的自然史及死亡预测因素（多中心前瞻性研究）
Spencer Lourens,Dharma B Sunjaya,Ashwani Singal et al.
Spencer Lourens et al.
Objective: To examine the natural history of acute alcoholic hepatitis (AH) and identify predictors of mortality for AH using data from a prospective multicenter observational study. ...
National Trends in the Incidence, Management, and Outcomes of Heart Failure Complications in Patients Hospitalized for ST-Segment Elevation Myocardial Infarction [0.03%]
我国急性ST段抬高型心肌梗死住院患者的并发症发生、管理和预后变化趋势：来自国家心血管病中心的 insights注册研究数据
Manyoo Agarwal,Sahil Agrawal,Lohit Garg et al.
Manyoo Agarwal et al.
Objective: To analyze contemporary trends in the incidence, management, and clinical outcomes of heart failure (HF) complications in patients hospitalized for ST-segment elevation myocardial infarction (STEMI) in the Unit...
Nonexercise Estimated Cardiorespiratory Fitness and Mortality Due to All Causes and Cardiovascular Disease: The NHANES III Study [0.03%]
基于非运动估算的心肺适能与全因和心血管疾病死亡率的关系——国家健康和营养调查Ⅲ研究
Yanan Zhang,Jiajia Zhang,Jie Zhou et al.
Yanan Zhang et al.
Objective: To investigate associations of estimated cardiorespiratory fitness (eCRF) and all-cause and cardiovascular disease (CVD) mortality in a representative US population. ...