Z-alpha1-antitrypsin polymers and small airways disease: a new paradigm in alfa-1 anti-trypsin deficiency-related COPD development? [0.03%]
Z-α1-抗胰蛋白酶多聚体与小气道疾病：α1抗胰蛋白酶缺乏症相关慢阻肺发病的新范式？
Laura Pini,Laura Tiberio,Marianna Arici et al.
Laura Pini et al.
The presence of Alpha1-Antitrypsin (AAT) polymers, known to promote a sustained pro-inflammatory activity, has been previously demonstrated in bronchial biopsies of subjects with Z-AAT deficiency (AATD) suggesting a possible role in the dev...
Research data communication strategy at the time of pandemics: a retrospective analysis of the Italian experience [0.03%]
突发公共卫生事件中的科研数据传播战略——以意大利为例的回顾性分析
Danilo Buonsenso,Davide Pata,Chiara Rocchetti et al.
Danilo Buonsenso et al.
Coronavirus pandemic has radically changed the scientific world. During these difficult times, standard peer-review processes could be too long for the continuously evolving knowledge about this disease. We wanted to assess whether the use ...
Federico Raimondi,Caterina Conti,Luca Novelli et al.
Federico Raimondi et al.
Pulmonary Tumor Thrombotic Microangiopathy (PTTM) is a rare condition associated with neoplastic disorders, predominantly gastric cancer, leading to pre-capillary Pulmonary Hypertension (PH). The pathologic mechanism involved is a fibrocell...
Predictors of severity and in-hospital mortality in patients with influenza [0.03%]
流感患者的病情严重程度及住院死亡率的影响因素分析
Mariana Serino,Nuno Melo,João Paulo Caldas et al.
Mariana Serino et al.
Influenza virus is a common agent of acute respiratoty infections during epidemic periods. It is a major cause of morbidity and mortality and represent a significant burden on the healthcare system. We aimed to evaluate predictors of severi...
BCG vaccination impact on mortality and recovery rates in COVID-19: A meta-analysis [0.03%]
BCG疫苗对COVID-19死亡率和恢复率影响的Meta分析研究
Surjit Singh,Daisy Khera,Ankita Chugh et al.
Surjit Singh et al.
COVID-19 is a pandemic caused by SARS-CoV-2 virus which is a very worrisome public health emergency. In this study, we compared the mortality rate and recovery rate in countries with and without BCG vaccination policy. The data of mortality...
Ana Martins da Costa,Rafael Teixeira,Eduardo M Vilela et al.
Ana Martins da Costa et al.
Exercise is a pivotal physiological activity, associated with benefits. Whilst the importance of physical activity is consensual along different steps of the cardiovascular (CV) continuum, there has been interest in assessing the CV adaptat...
Giorgio Ciprandi,Maria Angela Tosca
Giorgio Ciprandi
The post-viral acute cough (PAC) is a widespread symptom, mainly in childhood and adolescence, and is usually associated with an acute upper respiratory infection, namely the common cold. The use of cough relievers is, therefore, impressive...
Tobacco use and nicotine dependence among patients with diabetes and hypertension in Ballabgarh, India [0.03%]
印度Ballabgarh糖尿病和高血压患者中的烟草使用与尼古丁依赖性问题
Rakesh Kumar,Shashi Kant,Ankit Chandra et al.
Rakesh Kumar et al.
Tobacco use is one of the most important modifiable risk factors for cardiovascular mortality and has a synergistic effect with diabetes and hypertension. This study was conducted to estimate the prevalence of tobacco use and nicotine depen...
Prolonged non-invasive respiratory supports in a COVID-19 patient with severe acute hypoxemic respiratory failure [0.03%]
序贯呼吸支持治疗新型冠状病毒感染者重症急性低氧性呼吸衰竭一例
Andrea Lanza,Maurizio Sommariva,Sara Mariani et al.
Andrea Lanza et al.
A pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 was declared in 2020. Severe cases were characterized by the development of acute hypoxemic respiratory failure (AHRF) requiring advanced respiratory support. However,...
Features and behavior of valvular abnormalities in adolescent and adult patients in mucopolysaccharidosis: an echocardiographic study [0.03%]
黏多糖贮积症青少年及成人患者瓣膜病变的特征和行为：超声心动图研究
Domenico Galzerano,Seemi Saba,Abdullah Al Sergani et al.
Domenico Galzerano et al.
Mucopolysaccharidoses, a rare inherited disorder of lysosomal storage, account for less than 0.1% of all genetic diseases. The penetrance is highly variable and clinically it varies from severe fetal-neonatal forms to attenuated diseases di...