Clinical Response to Baricitinib in Monogenic Lupus: Real-World Evidence from a Case Series of Seven Patients [0.03%]
Baricitinib治疗单基因狼疮的临床疗效：七例患者的系列研究真实世界证据分析
Sulaiman M Al-Mayouf,Ali AlAsmari,Alhanouf Al-Saleem
Sulaiman M Al-Mayouf
Background: Monogenic lupus is a rare, early-onset form of lupus caused by high-penetrance genetic variants, with diverse clinical features and a central role for type I interferon (IFN-I) in its pathogenesis. Standard tr...
Age-Related Microbiota Signatures in Inflammatory Diseases: Comparative Insights into Paediatric and Adult Crohn's Disease, Ulcerative Colitis, and Spondyloarthritis [0.03%]
炎症性疾病的年龄相关微生物标志物：儿童和成人克罗恩病、溃疡性结肠炎及脊柱关节炎的比较研究
Giancarlo Gimignani,Alessandro Borello,Cristina Panetta et al.
Giancarlo Gimignani et al.
Objectives: The study investigated the relationship among the human microbiota in the development and progression of inflammatory bowel diseases (IBD), specifically Crohn's Disease (CD) and Ulcerative Colitis (UC), as wel...
Emerging Targets in Psoriatic Arthritis: Dual IL-17A/F and Selective TYK2 Inhibition in a Clinical Perspective [0.03%]
从临床角度审视银屑病关节炎的新兴靶点：白介素-17A/F双效抑制及TYK2选择性抑制
Violeta Dimopoulou,Maria Nitsa,Christos Koutsianas
Violeta Dimopoulou
Psoriatic arthritis (PsA) is a multifaceted immune-mediated inflammatory disease with several unmet therapeutic needs, and many patients fail to achieve comprehensive disease control with existing treatments. This has driven the exploration...
Beyond Clinical Trials: Experience with Bimekizumab in 3 Challenging Cases of Psoriatic Arthritis [0.03%]
贝拉西尤单抗治疗3例银屑病关节炎的临床经验
Evangelos Papadimitriou,Ioanna Katsigianni,Marina Papoutsaki et al.
Evangelos Papadimitriou et al.
Background: Psoriatic arthritis (PsA) is a multi-domain inflammatory disease affecting skin, nails and the musculoskeletal system, often accompanied by comorbidities that complicate the management of patients. Although se...
Patients' Journey and Burden of Disease Among Patients with Axial Spondyloarthritis in Greece: A Cross-Sectional Online Survey [0.03%]
希腊轴性脊柱关节炎患者的疾病负担和就医历程：横断面在线调查
Katerina Lioliou,Dimitra I Lampropoulou,Garyfallia Stefanou et al.
Katerina Lioliou et al.
Objective/aim: This study investigates the patient journey and humanistic and economic burden of axial spondyloarthritis (axSpA) in Greece, addressing a gap in real-world data on patient experiences. ...
The Clinical Significance and Therapeutic Management of Dactylitis and Enthesitis in Psoriatic Arthritis [0.03%]
银屑病性关节炎的远端指(趾)炎和附着点炎的临床意义及治疗对策
Eleftherios Pelechas,Panagiota G Karagianni,Evripidis Kaltsonoudis
Eleftherios Pelechas
Introduction: Dactylitis and enthesitis are hallmark musculoskeletal manifestations of psoriatic arthritis, often signifying a more severe disease phenotype. These domains not only aid early diagnosis but are also associa...
The Pathophysiological Significance of Dual Inhibition of IL-17A and IL-17F in Psoriatic Arthritis and Axial Spondyloarthritis [0.03%]
白细胞介素17A和17F双重抑制在银屑病关节炎及轴向脊柱关节炎中的病理生理意义研究
Olga Katsouli,Vasileios Lainis,Andreas V Goules et al.
Olga Katsouli et al.
Objective: Spondylarthritides (SpA), including psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) are immune-mediated diseases in which the IL-23/IL-17 axis plays a central role. IL-17A inhibition is already a ...
Current and Emerging Therapies for Uveitis in Axial Spondyloarthritis: A Scoping Review [0.03%]
强轴型脊柱关节炎葡萄膜炎的当前和新兴疗法：系统回顾
Dimitrios Deligeorgakis,Elpida Skouvaklidou,Vasileios Skepastianos et al.
Dimitrios Deligeorgakis et al.
Aim: Uveitis is a common and potentially vision-threatening extra-musculoskeletal manifestation of axial spondyloarthritis (axSpA). Various biologic (bDMARD), as well as targeted synthetic (tsDMARD) disease-modifying anti...
Sofia Karagianni,Niki Kyriazi,Nikolaos Michalakeas et al.
Sofia Karagianni et al.
Psoriatic arthritis (PsA) and axial Spondyloarthritis (axSpA) share some common therapeutic options, namely TNF-inhibitors, anti-IL-17 and JAK-inhibitors. Despite the wealth of choices, often patients do not respond to the first b/tsDMARDs,...
Effect of Diet and Dietary Supplements on Gout-Related Outcomes: A Systematic Review of Randomised Controlled Trials [0.03%]
饮食及膳食补充剂对痛风的影响：随机对照试验的系统评价
Eleni C Pardali,Arriana Gkouvi,Kalliopi Nasiou et al.
Eleni C Pardali et al.
Objective: Gout is an inflammatory arthritis caused by elevated serum uric acid (SUA) concentrations, leading to monosodium urate crystal deposition in the joints and clinical symptoms. Various dietary supplements and die...