Dimitrios Deligeorgakis,Elpida Skouvaklidou,Christina Adamichou
Dimitrios Deligeorgakis
Despite advances in the management of systemic lupus erythematosus (SLE), it remains a chronic disease with frequent flares, requiring constant medical care, laboratory exams, hospitalisations, and the use of immunosuppressive drugs and cor...
Evolving Concepts in Treat-to-Target Strategies for Systemic Lupus Erythematosus [0.03%]
系统性红斑狼疮治疗目标策略的演变概念
Dionysis Nikolopoulos,Maria Helena Lourenço,Roberto Depascale et al.
Dionysis Nikolopoulos et al.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterised by a wide range of symptoms and a risk for irreversible organ damage, leading to increased morbidity and mortality. To improve long-term outcomes, inno...
The NYMERIA Study: A Real-World, Multicentre Contemporary Assessment of Disease- and Patient-Related Burden and Treatment Strategies in Patients with Systemic Lupus Erythematosus [0.03%]
NYMERIA研究：系统性红斑狼疮患者疾病及相关负担和治疗策略的多中心当代真实世界评估
George Bertsias,Antonis Fanouriakis,Marina Bartsakoulia et al.
George Bertsias et al.
Systemic lupus erythematosus (SLE) has a spectrum of phenotypes. Its management should target remission or low disease activity, prevention of relapses and organ damage, minimisation of drug-related harms, and optimisation of health-related...
Rapid and Remarkable Response to Rituximab in a Case of Lupus Enteritis: Challenging the Norm [0.03%]
利妥昔单抗治疗狼疮性肠炎快速显效的病例报告——挑战常规思维
Albader Hamza Hussein,Bayan Lafi Altamimi
Albader Hamza Hussein
Lupus enteritis is a rare gastrointestinal complication of systemic lupus erythematosus (SLE) associated with significant morbidity and mortality. Rituximab, a monoclonal antibody targeting CD20-positive B cells, has shown promise in refrac...
Diagnosing and Treating Systemic Juvenile Idiopathic Arthritis and Adult-Onset Still's Disease as Part of the Still's Disease Continuum [0.03%]
Still病谱系中的系统性幼年特发性关节炎和成人斯蒂尔病的诊断与治疗
Apostolos Kontzias,Olga Petryna,Priscila Nakasato et al.
Apostolos Kontzias et al.
Aim: We have summarised the existing evidence supporting the concept that systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease (AOSD) are part of the same Still's disease spectrum. ...
Focus on Filgotinib in Rheumatoid Arthritis: A Trial-Based Review [0.03%]
基于临床试验的Filgotinib治疗风湿性关节炎的效果分析
Elpida Skouvaklidou,Dimitrios Deligeorgakis,Anastasia Skalkou et al.
Elpida Skouvaklidou et al.
Janus kinases (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway is involved in pathophysiologic cascade of a notable number of rheumatic diseases. The development of JAK inhibitors has expanded treatment choices in rheum...
Konstantinos D Vassilakis,Konstantina Magiouf,Stefan Siebert et al.
Konstantinos D Vassilakis et al.
As our research interest and knowledge increases in the field of Spondyloarthritis, new aspects also emerge as regards to their therapeutic approach. JAK inhibitors (JAKi) are a relatively new treatment option, aiming molecules in the JAK-S...
The Effect of JAK Inhibitors on Patient-Reported Outcomes in Psoriatic Arthritis [0.03%]
JAK抑制剂对银屑病关节炎患者报告结果的影响
Sotirios G Tsiogkas,Carlo Perricone,Dimitrios P Bogdanos
Sotirios G Tsiogkas
Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects the joints and skin of patients with psoriasis. In this review we aimed to summarise the available evidence regarding the effect of Janus...
Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism with JAK Inhibitors versus TNF Inhibitors in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis [0.03%]
Janus激酶抑制剂与肿瘤坏死因子抑制剂治疗类风湿关节炎患者发生主要心血管事件和静脉血栓栓塞的风险比较：系统评价和 meta 分析
Styliani Partalidou,Dimitrios Patoulias,Kleopatra Deuteraiou et al.
Styliani Partalidou et al.
Objective: The aim of this study was to compare the risk of major cardiovascular events (MACE) and venous thromboembolic events (VTE) between tumour necrosis factor (TNF) and Janus kinase (JAK) inhibitors in patients with...
Anakinra for Refractory Pseudogout in Patients with End-stage Renal Disease on Haemodialysis [0.03%]
终末期肾病血液透析患者的难治性假痛风应用安那金拉治疗
Christina Antoniadou,Nikolaos Fytanidis,Vasileios Devetzis et al.
Christina Antoniadou et al.
Calcium pyrophosphate deposition (CPPD) arthritis is the second most common type of crystal-induced arthritis after gout. Acute flares are commonly treated with non-steroidal anti-inflammatory drugs, intra-articular or short-term systemic g...