Genetic diversity and epidemiology of accessory gene regulator loci in Clostridioides difficile [0.03%]
艰难梭菌中辅助基因调节位点的遗传多样性和流行病学研究
Yuta Okada,Shu Okugawa,Mahoko Ikeda et al.
Yuta Okada et al.
Quorum sensing is known to regulate bacterial virulence, and the accessory gene regulator (agr) loci is one of the genetic loci responsible for its regulation. Recent reports examining Clostridioides difficile show that two agr loci, agr1 a...
Prolonged viral shedding and new mutations of COVID-19 could complicate the control of the pandemic [0.03%]
COVID-19的病毒长时间排出和新突变可能会使疫情控制更加复杂
Chieh-Fan Chen,Tung-Yuan Tsai,Chen-Hui Yu et al.
Chieh-Fan Chen et al.
The studies of coronavirus disease 2019 (COVID-19) have mainly focused on epidemiological and clinical features of patients, but transmission dynamics of SARS-CoV-2 virus after patients have recovered is still poorly understood. Here we rep...
Tracking the genome of four Pseudomonas aeruginosa isolates that have a defective Las quorum-sensing system, but are still virulent [0.03%]
追踪四个铜绿假单胞菌分离株的基因组，这些分离株的Las群体感应系统有缺陷，但仍具有毒力
Enrique Martínez-Carranza,Selene García-Reyes,Abigail González-Valdez et al.
Enrique Martínez-Carranza et al.
In this work we analysed the whole genome extended multilocus sequence typing (wgMLST) of four Pseudomonas aeruginosa strains that are characterized by being virulent despite having a defective Las quorum-sensing (QS) system, and compare th...
IgG response to Mycobacterium tuberculosis non-polar lipids and sonicated extracts among tuberculous meningitis patients [0.03%]
结核性脑膜炎患者对结核分枝杆菌非极性脂质和超声提取物的IgG反应
Prashant Giribhattanavar,Chris Pirson,Kavitha Kumar et al.
Prashant Giribhattanavar et al.
Introduction: The diagnosis of tuberculous meningitis (TBM) is a major global health concern due to its protean nature. There is a need to identify better biomarkers for the rapid and definitive diagnosis of TBM. Lipids h...
Updated functional annotation of the Mycobacterium bovis AF2122/97 reference genome [0.03%]
牛分枝杆菌AF2122/97参考基因组的功能注释更新
Damien Farrell,Joseph Crispell,Stephen V Gordon
Damien Farrell
Mycobacterium bovis AF2122/97 is the reference strain for the bovine tuberculosis bacillus. Here we report an update to the M. bovis AF2122/97 genome annotation to reflect 616 new protein identifications that replace many of the old hypothe...
Phaeohyphomycosis caused by Diaporthe phaseolorum in an immunocompetent patient in Thailand: a case report [0.03%]
泰国免疫功能正常患者因Diaporthe phaseolorum引起的黑霉病：病例报告
Kulwadee Laosakul,Sirida Youngchim,Mati Chuamanochan et al.
Kulwadee Laosakul et al.
Phaeohyphomycosis is caused by a large, heterogeneous group of darkly pigmented fungi. It is an infrequent infection in humans. However, the prevalence has been increasing in recent years especially in immunocompromised patients. Diaporthe ...
Using next-generation sequencing of microRNAs to identify host and/or pathogen nucleic acid signatures in samples from children with biliary atresia - a pilot study [0.03%]
使用microRNA的下一代测序来识别胆道闭锁儿童样本中的宿主和/或病原体核酸特征-一个初步研究
Melvyn Smith,Mark Zuckerman,Apsara Kandanearatchi et al.
Melvyn Smith et al.
Biliary atresia (BA) is a progressive disease affecting infants resulting in inflammatory obliteration and fibrosis of the extra- and intra-hepatic biliary tree. BA may be grouped into type 1 isolated; type 2 syndromic, where other congenit...
Successful treatment of a unique chronic multi-bacterial scalp infection with N-chlorotaurine, N-bromotaurine and bromamine T [0.03%]
N-氯琥珀酸、N-溴琥珀酸和四溴化氨基甲烷对独特慢性多细菌头皮感染的成功治疗
Anthony M Kyriakopoulos,Markus Nagl,Dorothea Orth-Höller et al.
Anthony M Kyriakopoulos et al.
Microbial species can act in synergy to circumvent environmental stress conditions and survive. In addition, biofilms are a serious public-health issue globally and constitute a clinical emergency. Infection persistence, increased morbidity...
Detection of New Delhi metallo-beta-lactamase enzyme gene bla NDM-1 associated with the Int-1 gene in Gram-negative bacteria collected from the effluent treatment plant of a tuberculosis care hospital in Delhi, India [0.03%]
印度新德里一家结核病护理医院废水处理厂采集的阴性杆菌中与Int-1基因相关的新型德里金属β-内酰胺酶基因bla NDM-1的检出
Amit Aggarwal,Manpreet Bhalla,Khan Hena Fatima
Amit Aggarwal
Background: Organisms possessing the bla NDM-1 gene (responsible for carbapenem resistance) with a class-1 integron can acquire many other antibiotic resistance genes from the community sewage pool and become multidrug-re...
Abiotrophia defectiva endophthalmitis following routine cataract surgery: the first reported case in the United Kingdom [0.03%]
白内障手术后出现Abiotrophia defectiva眼内炎：英国首次报告此例
Madalina Chihaia,James Richardson-May,Layth Al-Saffar et al.
Madalina Chihaia et al.
Introduction: Abiotrophia defectiva is a fastidious organism that has been implicated in severe infections such as endocarditis in immunocompetent patients. Modern tools are available to aid identification, but the main c...