Meta-analysis of functional genomics studies reveals conserved cellular pathways required by viruses of pandemic concern [0.03%]
系统功能基因组学 meta 分析识别大流行病毒所依赖的保守细胞通路
Aaron M Brice,Alessandro T Caputo,Cameron R Stewart
Aaron M Brice
The coronavirus disease 2019 pandemic illustrated the need to develop medical countermeasures against emerging infectious diseases. As viruses rely on cellular machinery for replication, host-directed antivirals (HDAs) may complement conven...
Type VI secretion system-mediated bacterial antagonism in the classroom [0.03%]
利用VI型分泌系统在课堂上进行细菌间的对抗实验
Alejandro Tejada-Arranz,Peter Ringel,Lin Lin et al.
Alejandro Tejada-Arranz et al.
The study of bacterial antagonism, and specifically type VI secretion system (T6SS)-mediated antagonism, has gained momentum over the last decade in research laboratories across the world. The T6SS is a molecular machine that mediates inter...
Preparation of culture plates demonstrating anti-Staphylococcus aureus activity of Penicillium sp. and their use as teaching materials [0.03%]
用作教学材料的展示Penicillium spp.抗金黄色葡萄球菌活性的培养平板的制备
Tomoe Ichikawa,Yoshio Ishibashi
Tomoe Ichikawa
Penicillin is recognized as one of the world's first antibiotics, originally derived from Penicillium sp. However, few students have directly observed the antibacterial activity of Penicillium sp. against bacterial pathogens. Therefore, we ...
Whole-genome sequencing of clinical methicillin-resistant Staphylococcus aureus isolates across hospitals in Mwanza, Tanzania [0.03%]
坦桑尼亚姆万扎多家医院临床耐甲氧西林金黄色葡萄球菌的全基因组测序
Vitus Silago,Lawrence Mapunda,Prisca Damiano et al.
Vitus Silago et al.
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of both healthcare-associated and community-acquired infections, characterized by limited treatment options and substantial morbidity and mortality, particularly in low- ...
Burden of extended-spectrum beta-lactamase-producing Enterobacteriaceae among cancer patients in Africa: a systematic review and meta-analysis [0.03%]
非洲癌症患者中产超广谱β内酰胺酶肠杆菌科的负担：系统评价和 Meta 分析
Henry Zamarano,Benson Musinguzi,Muzafaru Twinomujuni et al.
Henry Zamarano et al.
Background. Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) exacerbate infections in cancer patients in settings where antimicrobial resistance threatens health outcomes. This study estimated the prevalence of ESBL-P...
Microplate-based quantification of poly-γ-glutamic acid levels in biofilm samples [0.03%]
微平板法测定生物膜样品聚-γ-谷氨酸含量
David Stevenson,Cait E MacPhee,Nicola Stanley-Wall
David Stevenson
Poly-γ-glutamic acid (PGA) is a commercially useful biopolymer produced by many Bacillus species. PGA has a diverse range of applications across medicine and industry, generating significant interest in optimizing PGA production and enhanc...
Diversity and plant growth-promoting traits of endophytic bacteria isolated from maize cropped in organic and low-input agricultural systems in southern Brazil [0.03%]
从巴西南部有机和低投入农业系统中玉米内生细菌的多样性及促植物生长性状的研究
Dafila Santos Lima Fagotti,Josiane Fukami,Paula Cerezini et al.
Dafila Santos Lima Fagotti et al.
Plant growth-promoting bacteria (PGPB) may enhance plant growth and health through several mechanisms, contributing to sustainable agriculture. We isolated and characterized endophytic bacteria from stems of landrace maize (Zea mays L.) gro...
Management of infective endocarditis in a secondary care trust: a service evaluation of treatment outcomes and multidisciplinary involvement [0.03%]
英国某二级医疗保健机构感染性心内膜炎的管理：治疗效果与多学科参与的服务评估
Lisa Dwyer-Joyce,Mo Chung Kwok,Stephen Hughes et al.
Lisa Dwyer-Joyce et al.
Background. Infective endocarditis (IE) is a complex and life-threatening condition, requiring multidisciplinary team (MDT) input for optimal management. Objectives. This study aimed to review the demographics, infection management and clin...
Evaluating the impact of a laboratory teaching innovation: the case of the Bioskills at home kit [0.03%]
一种实验室教学创新的影响评估：Bioskills家用工具包案例分析
Bunmi B Omorotionmwan,Sarah Rayment,Karin Garrie et al.
Bunmi B Omorotionmwan et al.
Practical laboratory training is a key component of biosciences education, essential for developing critical skills and bridging the gap between theory and practice. The 'Bioskills at home kit', originally developed during the COVID-19 pand...
Reverse genetics approach for arteriviruses using circular polymerase extension reaction [0.03%]
采用-circle聚合酶展伸反应进行动脉病毒反向遗传学研究
Rabab T Hassanien,Wellesley Dittmar,Udeni B R Balasuriya et al.
Rabab T Hassanien et al.
The circular polymerase extension reaction (CPER) has emerged as a high-fidelity, versatile and rapid tool for generating infectious cDNA clones of positive-sense, single-stranded RNA viruses. Here, we implemented this strategy to generate ...