Effect of prenatal heparin-binding epidermal growth factor (HB-EGF) administration on necrotizing enterocolitis-induced lung injury in a murine model [0.03%]
孕鼠注射HB-EGF对新生小鼠坏死性肠炎致肺损伤的预防作用研究
Beverly Giang,Andrei Radulescu,Georgi Dianov Mladenov et al.
Beverly Giang et al.
Background: Necrotizing enterocolitis (NEC) is a gastrointestinal emergency in premature neonates. NEC is mediated by toll-like receptor-4 (TLR-4) and associated with lung injury. Previously, we showed that prenatal hepar...
Surgical treatment of proximal femur unicameral bone cysts in children: a retrospective single-center study [0.03%]
儿童股骨近端单纯性骨囊肿的手术治疗:一项单中心回顾性研究
Haibing Li,Xiao Fen Niu,Hang Su et al.
Haibing Li et al.
Objective: The aim of this study was to present clinical and radiological outcomes of surgical treatment for proximal femur unicameral bone cysts (UBCs) in children. ...
Robotic liver resection for hepatic focal nodular hyperplasia in children: comparison with open surgery [0.03%]
儿童机器人肝切除术治疗肝局部结节增生与开腹手术的比较研究
Xuan Wu,Min He,Yinbing Tang et al.
Xuan Wu et al.
Background: Robot-assisted surgery is becoming increasingly used in pediatric oncology. The present study aimed to evaluate the feasibility and safety of robotic liver resection (RLR) for hepatic focal nodular hyperplasia...
Brainstem microglial cell morphology in neonatal rats with necrotizing enterocolitis and the effects of prenatal heparin-binding epidermal growth factor-like growth factor [0.03%]
坏死性小肠结肠炎新生大鼠脑干微胶质细胞形态变化及其宫内HB-EGF干预效应
Vonita Chawla,Yomara S Mendez,Lorraine C Siebold et al.
Vonita Chawla et al.
Background: Necrotizing enterocolitis (NEC) is associated with increased neurodevelopmental impairment. Gut-brain interactions through the brainstem may be central to NEC-related microglia-driven neuroinflammation. Hepari...
Hector L Monforte,Michael Wilsey,Raquel Gonzalez
Hector L Monforte
The practice, art and science of surgical pathology for disease entities evolves continuously. Standards for diagnosis and management of Hirschsprung disease (HSCR), variants and related dysmotility disorders are no exception. Morphologic p...
Predictive value of plasma zonulin for postoperative Hirschsprung-associated enterocolitis [0.03%]
血浆zonulin预测术后哈契斯普龙病相关性肠炎的价值
Lihua Wu,Ya Gao,Ruijie Zhou et al.
Lihua Wu et al.
Background: Hirschsprung's disease (HSCR) is a functional obstruction of the gastrointestinal tract characterized by abdominal distension, constipation, and vomiting. The protein zonulin serves as a biomarker for intestin...
Strengthening collaboration within Europe: biliary atresia and the rise of the European Reference Networks [0.03%]
加强欧洲地区合作:胆道闭锁和欧洲参考网络的兴起
Omid Madadi-Sanjani,Christoph Slavetinsky,Marie Uecker
Omid Madadi-Sanjani
Biliary atresia (BA) is a rare and devastating cholangiopathy with an incidence of 1:15 000-20 000 in Europe. There is a consensus that BA and related rare diseases should be managed at centers of expertise. However, current BA care in Euro...
Exosome encapsulation of miR-205-5p suppresses neuroblastoma progression by targeting RUNX2 [0.03%]
微囊化miR-205-5p通过靶向RUNX2抑制神经母细胞瘤进展
Jiaxiang Tang,Qi Liu,Binyi Yang et al.
Jiaxiang Tang et al.
Objective: This study investigates the tumor-suppressive role of microRNA (miR)-205-5p in neuroblastoma (NB) and evaluates exosome-mediated delivery of miR-205-5p as a therapeutic strategy. ...
Impact of preoperative chemotherapy cycles on tumor resectability and surgical timing in hepatoblastoma: a retrospective analysis [0.03%]
术前化疗次数对肝母细胞瘤肿瘤可切除性及手术时机影响的回顾性分析研究
Chengdong Wang,Yeming Wu,Jia Shi et al.
Chengdong Wang et al.
Background: Hepatoblastoma (HB) is the most common malignant liver tumor in children. However, the optimal duration of preoperative chemotherapy remains unclear, particularly regarding its impact on tumor size and proximi...
Fetal therapy for congenital diaphragmatic hernia: past, present and future [0.03%]
先天性膈疝的胎儿治疗:过去、现在和未来展望
Nimrah Abbasi,Tim Van Mieghem,Greg Ryan
Nimrah Abbasi
Congenital diaphragmatic hernia (CDH) affects 1/2500-5000 infants and is associated with significant neonatal morbidity and mortality related to pulmonary hypoplasia and pulmonary hypertension. Current estimates of perinatal mortality are b...