Trajectory of fecal lactoferrin for predicting prognosis in ulcerative colitis [0.03%]
溃疡性结肠炎粪便乳铁蛋白轨迹与预后的预测价值研究
Rirong Chen,Li Li,Yizhe Tie et al.
Rirong Chen et al.
Objectives: To investigate the characteristics and prognostic value of fecal lactoferrin trajectories in ulcerative colitis (UC). Methods: ...
Advances in diagnosis and prediction for aggression of pure solid T1 lung cancer [0.03%]
纯固性T1期肺癌侵袭性的诊断和预后研究进展
Junhao Mu,Jing Huang,Min Ao et al.
Junhao Mu et al.
A growing number of early-stage lung cancers presenting as malignant pulmonary nodules have been diagnosed because of the increased adoption of low-dose spiral computed tomography. But pure solid T1 lung cancer with ≤3 cm in the greatest d...
Loss of chromosome 9p21 is associated with a poor prognosis in adenosquamous carcinoma of the pancreas [0.03%]
染色体缺失与胰腺腺鳞癌预后不良有关
Yina Jiang,Yinying Wu,Liwen Zhang et al.
Yina Jiang et al.
Adenosquamous carcinoma of the pancreas (ASCP) is a rare histological subtype of pancreatic cancer with a poor prognosis and a high metastasis rate. However, little is known about its genomic landscape and prognostic biomarkers. A total of ...
A pairwise radiomics algorithm-lesion pair relation estimation model for distinguishing multiple primary lung cancer from intrapulmonary metastasis [0.03%]
一种对多原发肺癌和肺内转移区分的成对影像组学算法-病灶配对关系估计模型方法
Ting-Fei Chen,Lei Yang,Hai-Bin Chen et al.
Ting-Fei Chen et al.
Background: Distinguishing multiple primary lung cancer (MPLC) from intrapulmonary metastasis (IPM) is critical for their disparate treatment strategy and prognosis. This study aimed to establish a non-invasive model to m...
Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review [0.03%]
激活蛋白2在乳腺癌发生发展中的作用：综述文章
Ahmed Amarah,Ahmed Adel Elsabagh,Amr Ouda et al.
Ahmed Amarah et al.
Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular functions. Since ATF2 p...
miR-181b-5p/SOCS2/JAK2/STAT5 axis facilitates the metastasis of hepatoblastoma [0.03%]
miR-181b-5p/SOCS2/JAK2/STAT5轴促进肝母细胞瘤的转移
Yong Lv,Xiaolong Xie,Guoyou Zou et al.
Yong Lv et al.
Introduction: Hepatoblastoma (HB) is a malignant liver tumor predominantly found in children and tumor metastasis is one of the main causes of poor prognosis in affected patients. The precise molecular mechanisms responsi...
Qiyuan Huang,Ruihao Zhou,Xuechao Hao et al.
Qiyuan Huang et al.
Owing to the advances in surgical technology, most solid tumours can be controlled by surgical excision. The priority should be tumour control, while some routine perioperative management might influence cancer progression in an unnoticed w...
Blockade of Syk modulates neutrophil immune-responses via the mTOR/RUBCNL-dependent autophagy pathway to alleviate intestinal inflammation in ulcerative colitis [0.03%]
Syk信号转导分子的阻断通过mTOR/RUBCNL依赖性自噬途径调节中性粒细胞免疫应答以缓解溃疡性结肠炎小鼠模型的肠道炎症反应
Fengqin Zhu,Dehuai Jing,Huihui Zhou et al.
Fengqin Zhu et al.
Background: Ulcerative colitis (UC) is a progressive chronic inflammatory disorder. Neutrophils play a critical role in regulating intestinal mucosal homeostasis in UC. Spleen tyrosine kinase (Syk) is involved in several ...
NDRG1 promotes endothelial dysfunction and hypoxia-induced pulmonary hypertension by targeting TAF15 [0.03%]
NDRG1通过靶向TAF15促进内皮功能障碍和缺氧诱导的肺动脉高压
Chengwei Li,Junzhu Lv,Gulinuer Wumaier et al.
Chengwei Li et al.
Background: Pulmonary hypertension (PH) represents a threatening pathophysiologic state that can be induced by chronic hypoxia and is characterized by extensive vascular remodeling. However, the mechanism underlying hypox...
The latest breakthrough on genetic characteristics of inflammatory bowel disease in Chinese and other East Asian ancestries [0.03%]
关于亚洲人群炎症性肠病遗传特性的最新研究进展
Han Gao,Zhanju Liu
Han Gao
Inflammatory bowel diseases (IBDs) are complex chronic disorders of the gastrointestinal tract with the following two subtypes: Crohn's disease and ulcerative colitis. Disease presentation and progression within and across IBDs, especially ...