Tissue Engineered Models of Adipose Tissue Dysfunction to Investigate Obesity-Related Comorbidities [0.03%]
用于研究肥胖相关并发症的脂肪组织功能障碍的组织工程模型
Lara Ece Celebi,Frank Ketchum,Dila Naz Bozkaya et al.
Lara Ece Celebi et al.
Emerging evidence suggests that adipose tissue is not just a fat depot but a metabolically active organ that plays a central role in connecting obesity with its comorbidities. Understanding the complex interactions between adipocytes and ne...
Computational Modeling and Simulation for Medical Devices: A Summary of the 2024 FDA/MDIC Symposium [0.03%]
医疗器械计算模型与模拟：2024年FDA/MDIC symposium概述
Brent A Craven,Christopher A Basciano,Payman Afshari et al.
Brent A Craven et al.
Computational modeling and simulation (CM&S) is a powerful tool that can be used to support the development, evaluation, and regulatory authorization of medical devices. CM&S can provide valuable insights into device performance, safety, an...
Mohammad Alsenaide,Ryan O&#x;Hare Doig,Dusan Losic et al.
Mohammad Alsenaide et al.
Chemical cues have been extensively explored in tissue engineering (TE). However, biophysical cues, such as electrical stimulation (ES) have recently gained attention for their capacity to enhance stem cell (SC) viability, proliferation, an...
Natural Melanin: A Multifunctional Biopigment for Advanced Biomedical Applications [0.03%]
天然黑色素：一种多功能生物色素在高级生物医学应用中的作用
Magdalena Bartolewska,Alicja Kosik-Kozioł,Anbreen Arif et al.
Magdalena Bartolewska et al.
Melanin, a widespread natural biopigment, has attracted growing attention owing to its multifunctional properties and potential in novel biomaterials. This review addresses the classification, biological sources, and extraction methodology ...
Predicting Procedural Outcomes in Transcatheter Aortic Valve Implantation: A Scoping Review of Numerical Patient-Specific Simulations [0.03%]
经导管主动脉瓣植入术预后研究的数值模拟文献综述
Benedetta Grossi,Letizia Maria Perri,Valeria Raona et al.
Benedetta Grossi et al.
Transcatheter Aortic Valve Implantation (TAVI)-related post-operative complications remain significant clinical challenges, and current in-silico simulations fall short in predicting them accurately, limiting their clinical applicability. T...
Cutting-Edge Approaches to Diagnosing and Treating Limb Ischemia in Peripheral Arterial Disease [0.03%]
外周动脉疾病肢体缺血的诊断和治疗新进展
Goodluck Okoro,Fortune K Owunnah,Catherine C Applegate et al.
Goodluck Okoro et al.
Peripheral Arterial Disease (PAD) is a common circulatory condition that leads to reduced blood flow to the limbs, often resulting in limb ischemia which can severely impact a patient's quality of life and increase the risk of amputation. E...
Samuel Dembowitz,Felix Rivera Moctezuma,Nicholas Zhang et al.
Samuel Dembowitz et al.
Cellular biophysical properties are increasingly linked to disease development, including muscular dystrophy, cancer, glaucoma, and other conditions. Transcription profiles of different types have been used to clarify the relationship betwe...
Mechanical Reinforcement and Growth Factor Delivery Strategies for In Situ Cartilage Repair [0.03%]
原位软骨修复的力学增强和生长因子递送策略
Amy Xie,Francesca Taraballi,Anita Quigley et al.
Amy Xie et al.
In situ cartilage engineering aims to repair damaged cartilage within the body by using biomaterials
such as hydrogels, often loaded with regenerative cells to support tissue formation at the injury
site. Hydrogels are promising can...
Review of in silico models of cerebral blood flow in health and pathology [0.03%]
脑健康和疾病状况下脑血流的计算模型综述
Stephen Payne,Tamás István Józsa,Wahbi K El-Bouri
Stephen Payne
In this review, we provide a summary of the state-of-the-art in the in silico modelling of cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in the transport of nutrients, including oxygen and ...
Soft robotics for physical simulators, artificial organs and implantable assistive devices [0.03%]
用于物理模拟器、人工器官和植入式辅助设备的软体机器人
Debora Zrinscak,Lucrezia Lorenzon,Martina Maselli et al.
Debora Zrinscak et al.
In recent years, soft robotics technologies enabled the development of a new generation of biomedical devices. The combination of elastomeric materials with tunable properties and muscle-like motions paved the way toward more realistic phan...