Yang Liu,Tiandong Chen,Ning Gu et al.
Yang Liu et al.
Tumors with high mortality rates are still a major threat to human survival and health worldwide. In recent years, cancer immunotherapy has made rapid clinical progress in eliminating cancers by activating the host's own immune system. Part...
Physiological closed-loop control in critical care: opportunities for innovations [0.03%]
重症监护中的生理闭环控制：创新机遇
Jin-Oh Hahn,Omer T Inan
Jin-Oh Hahn
Physiological closed-loop control (PCLC) systems are a key enabler for automation and clinician support in medicine, including, but not limited to, patient monitoring, diagnosis, clinical decision making, and therapy delivery. Existing body...
Advances in engineered exosomes towards cancer diagnosis and therapeutics [0.03%]
工程化外泌体在癌症诊断和治疗中的进展
Tanziela Tanziela,Xiawei Dong,Jing Ye et al.
Tanziela Tanziela et al.
Exosomes have emerged as natural nanocarriers and are advantageous in the field of nanomedicine due to their lipid bilayer membrane comprising many proteins, nucleic acids and cell debris. Exosomes are secreted from all types of living cell...
Defne Yigci,Misagh Rezapour Sarabi,Merve Ustun et al.
Defne Yigci et al.
Glioma is one of the most malignant types of cancer and most gliomas remain incurable. One of the hallmarks of glioma is its invasiveness. Furthermore, glioma cells tend to readily detach from the primary tumor and travel through the brain ...
Sushila Maharjan,Diana Priscills Bonilla-Ruelas,Gorka Orive et al.
Sushila Maharjan et al.
As the field of tissue engineering and regenerative medicine progresses, the possibility for artificial organs to restore normal tissue functions seems to become more feasible. However, a major challenge in the long-term culture of the engi...
Recent progress in the use of thermogelling polymers for treatment of ophthalmic conditions [0.03%]
热凝胶聚合物在眼科疾病治疗中的最新进展
Jasmin Omar,Cécile A Dreiss,Xian Jun Loh
Jasmin Omar
Ocular diseases have serious implications on patients' lives, with the majority causing blindness if left untreated. In 2020 it was estimated that 43 million people were blind worldwide which is expected to increase to 61 million by 2050. D...
Hydrogel and nanoparticle carriers for kidney disease therapy: trends and recent advancements [0.03%]
用于肾脏疾病治疗的水凝胶和纳米粒子载体：趋势与近期进展
Xurui Gu,Zhen Liu,Yifan Tai et al.
Xurui Gu et al.
Achieving local therapeutic agent concentration in the kidneys through traditional systemic administration routes have associated concerns with off-target drug effects and toxicity. Additionally, kidney diseases are often accompanied by co-...
Daniel A Cruz,Melissa L Kemp
Daniel A Cruz
Systems biology models are typically considered across a spectrum from mechanistic to abstracted description; however, the lines between these forms of modeling are increasingly blurred. Ever-increasing computational power is providing nove...
Cancer-on-chip technology: current applications in major cancer types, challenges and future prospects [0.03%]
癌症芯片技术：在主要癌症类型中的当前应用、挑战和未来前景
Zakaria Baka,Marie Stiefel,Agathe Figarol et al.
Zakaria Baka et al.
Conventional 2D cell cultures are widely used for the development of new anticancer drugs. However, their relevance asin vitromodels is increasingly questioned as they are considered too simplistic compared to complex, three-dimensionalin v...
Soft wearable sensors for monitoring symptoms of COVID-19 and other respiratory diseases: a review [0.03%]
用于监测COVID-19及其他呼吸道疾病症状的软可穿戴传感器：综述
Yuxuan Liu,Darpan Shukla,Holly Newman et al.
Yuxuan Liu et al.
The COVID-19 pandemic has put extraordinary stress on medical systems and global society more broadly. The condition of infected patients may deteriorate rapidly due to overburdened hospital systems. This raises an urgent need for real-time...