3D Bioprinting cell-laden bioinks for engineering neural tissues and potential models for Parkinson's disease [0.03%]
用于工程神经组织和潜在帕金森病模型的含细胞生物墨水的3D生物打印
Maria Alejandra Castilla Bolanos
Maria Alejandra Castilla Bolanos
Parkinson's disease (PD) is the second most common age-related neurodegenerative disorder after Alzheimer's disease, affecting over ten million people worldwide. It is characterized by motor symptoms such as tremors, rigidity, and gait dist...
Ivana Vasic,Todd C McDevitt
Ivana Vasic
Pluripotent stem cell-derived organoids providein vitromodels of development and disease that can be used for a wide range of biomedical applications, including high-throughput screens or regenerative medicine. The ability of stem cells to ...
Engineering bone from fat: a review of the in vivo mechanisms of adipose derived stem cell-mediated bone regeneration [0.03%]
由脂肪衍生干细胞介导的骨再生的体内机制综述
Allison L Horenberg,Alexandra N Rindone,Warren L Grayson
Allison L Horenberg
Adipose-derived stromal/stem cells (ASCs) have considerable potential to promote bone regeneration due to their ease of isolation, abundance, and osteogenic capacity. However, despite two decades of research, studies of the precise mechanis...
Ziyi Yu,Nan Jiang,Sergei G Kazarian et al.
Ziyi Yu et al.
For decades, diabetes mellitus has been of wide concern with its high global prevalence, resulting in increasing social and financial burdens for individuals, clinical systems and governments. Continuous glucose monitoring (CGM) has become ...
Modeling metastasis: engineering approaches to study the metastatic cascade [0.03%]
转移的建模：研究转移级联的工程方法
Hawley C Pruitt,Sharon Gerecht
Hawley C Pruitt
Tumor progression and metastasis requires a complex interplay between tumor cells and their surrounding environment. Conventional 2D and 3D tissue culture models lack the precision and spatiotemporal control required to accurately model the...
Scaffold-free and scaffold-based cellular strategies and opportunities for cornea tissue engineering [0.03%]
无支架及有支架细胞疗法在角膜组织工程中的策略及前景研究
Zahid Hussain,Renjun Pei
Zahid Hussain
The human cornea is a dome-shaped, multilaminar, transparent, immune-privileged membrane in the front of the eye's optical system. The cornea protects the intraocular parts and letting light into the interior for an image formation on the r...
Joaquim M Oliveira,Viviana P Ribeiro,Rui L Reis
Joaquim M Oliveira
The osteochondral (OC) tissue is one of the most hierarchical and complex structures known and it is composed by two main compartments of hyaline articular cartilage and subchondral bone. It exhibits unique cellular and molecular transition...
Progress and challenges in biomarker enrichment for cancer early detection [0.03%]
癌症早期检测中生物标志物捕获的进展与挑战
Prima Dewi Sinawang,Fernando Soto,Mehmet Ozgun Ozen et al.
Prima Dewi Sinawang et al.
Cancer cells generate and secrete diverse molecules into circulation that could be used as signatures for health and disease. A significant obstacle in detecting such molecules derives from their low signal-to-noise ratio in subsequent down...
Kinematic design of linkage-based haptic interfaces for medical applications: a review [0.03%]
基于机架的医疗应用触觉用户界面的运动设计：综述
Ali Torabi,Ali A Nazari,Everly Conrad-Baldwin et al.
Ali Torabi et al.
A haptic interface recreates haptic feedback from virtual environments or haptic teleoperation systems that engages the user's sense of touch. High-fidelity haptic feedback is critical to the safety and success of any interaction with human...
Current and emerging techniques for oral cancer screening and diagnosis: a review [0.03%]
口腔癌筛查和诊断的现有及新兴技术：综述性文章
Sapna R Bisht,Pratibha Mishra,Deep Yadav et al.
Sapna R Bisht et al.
Oral cancer causes over 350 000 deaths annually worldwide. Although most cases are in Asia, the incidence of oral cancer is rising across the world. Despite recent advances in screening methods, oral cancer remains a significant cause of mo...