The impact of liver disease on mortality in cystic fibrosis - a systematic review protocol [0.03%]
囊性纤维化肝病对死亡率影响的系统评价方案
Ao Sasame,Lucy Connolly,Emer Fitzpatrick et al.
Ao Sasame et al.
Background Cystic fibrosis (CF) is a multiorgan disease affecting the lungs pancreas and gastrointestinal tract. Pulmonary complications are the most common manifestation of the disease. Recent advances in the treatment of pulmonary complic...
Rare Disease Research Partnership (RAinDRoP): a collaborative approach to identify research priorities for rare diseases in Ireland [0.03%]
罕见病研究伙伴关系(RAinDRoP):爱尔兰罕见病研究优先事项的协作识别方法
Suja Somanadhan,Emma Nicholson,Emma Dorris et al.
Suja Somanadhan et al.
Background: Rare diseases are individually rare, but collectively these conditions are common. Research on rare diseases are currently focused on disease-specific needs rather than a life-course perspective. The Rare Disease Research Partne...
Neuronal response variability as a product of divisive normalization; neurobiological implications at a macroscale level [0.03%]
基于除法归一化的神经元反应变异性的产生及宏观尺度下的神经生物学含义
Kathy L Ruddy,David M Cole,Colin Simon et al.
Kathy L Ruddy et al.
The occurrence of neuronal spikes recorded directly from sensory cortex is highly irregular within and between presentations of an invariant stimulus. The traditional solution has been to average responses across many trials. However, with ...
Steps Ahead: optimising physical activity in adults with cystic fibrosis: Study Protocol for a pilot randomised trial using wearable technology, goal setting and text message feedback [0.03%]
走在时间前面:囊性纤维化成人患者身体活动的优化:使用可穿戴技术、目标设定和短信反馈进行随机对照试验的研究方案
Maire Curran,Audrey C Tierney,Louise Collins et al.
Maire Curran et al.
Background: Physical activity (PA) and exercise are widely documented as key components in the management of cystic fibrosis (CF). In recent years there have been significant improvements in telehealth, in particular; wearable technology, s...
Transition from child-centred to adult-oriented healthcare systems for young people with neurodisability: a scoping review protocol [0.03%]
神经功能障碍青年从以儿童为中心过渡到以成人为主的医疗保健系统的转变:一项系统综述协议
Jennifer Fortune,Paul Murphy,Nabil Merchant et al.
Jennifer Fortune et al.
Background: The transition from child-centred to adult-oriented healthcare is a challenging time for young people with neurodisability. As the prevalence of neurodisability increases, greater numbers of young people will eventually transfer...
Housing with support for older people: a mixed-methods systematic review protocol [0.03%]
支持老年人的住房:混合方法系统评价方案
Camille Coyle,Sarah Buggy,Olivia Cagney et al.
Camille Coyle et al.
Background: The implementation of housing with support is rapidly expanding, particularly as life expectancy is increasing throughout the world. This expansion is likely to intensify in the context of coronavirus disease 2019 (COVID-19), wh...
Transcutaneous tibial nerve stimulation for the treatment of bladder storage symptoms in people with multiple sclerosis: Protocol of a single-arm feasibility study [0.03%]
胫神经经皮电刺激治疗多发性硬化症患者的膀胱贮存症状:单组可行性研究方案
Hawra B Al Dandan,Rose Galvin,Katie Robinson et al.
Hawra B Al Dandan et al.
Background: Neurogenic lower urinary tract dysfunction (NLUTD) is common among people with multiple sclerosis (MS) with a pooled prevalence of 68.41% using self-report measures and 63.95% using urodynamic studies. Transcutaneous tibial nerv...
Is optometry ready for myopia control? Education and other barriers to the treatment of myopia [0.03%]
控制近视的需求是否已经来临?教育及其他影响近视治疗的因素
Saoirse McCrann,Ian Flitcroft,James Loughman
Saoirse McCrann
Background: With the increasing prevalence of myopia there is growing interest in active myopia control. However, the majority of progressive myopes are still prescribed single vision spectacles. This prospective study aims to elucidate the...
Barriers and enablers to screening and diagnosing depression and diabetes distress in people with type 2 diabetes mellitus; protocol of a qualitative evidence synthesis [0.03%]
在二型糖尿病患者中筛查和诊断抑郁症和糖尿病困扰的障碍与促进因素;定性证据综合协议
Niamh McGrath,Sheena McHugh,Patricia M Kearney et al.
Niamh McGrath et al.
Background: Depression and diabetes distress are common in people with type 2 diabetes (T2DM). These conditions are independently associated with poorer T2DM outcomes and increased healthcare utilisation and costs. Questions remain regardin...
Covid-19 Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing: a study protocol [0.03%]
新冠-19 估计社区中症状性疾病负担及公共卫生措施对身体、精神和社会健康的影响:研究方案
M Isabela Troya,Ali Khashan,Patricia Kearney et al.
M Isabela Troya et al.
Introduction: Covid-19 was declared a pandemic in March 2020. Since then, governments have implemented unprecedented public health measures to contain the virus. This study will provide evidence to inform responses to the pandemic by: i) es...