Optimal use of meningococcal serogroup B vaccines: moving beyond outbreak control [0.03%]
脑膜炎球菌B型疫苗的最适应用：超越疫情控制阶段
Paul Balmer,Laura J York
Paul Balmer
Neisseria meningitidis is a major cause of meningitis and septicemia globally. Vaccines directed against N. meningitidis serogroup B (MenB) have been used to control sporadic and sustained disease in industrialized and non-industrialized co...
Victoria A Brentville,Suha Atabani,Katherine Cook et al.
Victoria A Brentville et al.
The interplay between tumours and the immune system has long been known to involve complex interactions between tumour cells, immune cells and the tumour microenvironment. The progress of checkpoint inhibitors in the clinic in the last deca...
Healthcare-associated infections: potential for prevention through vaccination [0.03%]
通过疫苗接种预防医院感染的潜力
E David G McIntosh
E David G McIntosh
The challenge of healthcare-associated infections is compounded by the higher incidence of resistant organisms and the decreasing utility of antimicrobial agents. Historic and current vaccines have already contributed to reductions in healt...
Eva Dahlén,Niina Veitonmäki,Per Norlén
Eva Dahlén
Following the clinical success of immune checkpoint antibodies targeting CTLA-4, PD-1 or PD-L1 in cancer treatment, bispecific antibodies are now emerging as a growing class of immunotherapies with potential to further improve clinical effi...
The influence of radiation in the context of developing combination immunotherapies in cancer [0.03%]
放射疗法在癌症免疫联合治疗中的作用
Jamie Honeychurch,Timothy M Illidge
Jamie Honeychurch
In addition to tumouricidal activity, radiotherapy is now recognized to display potent immunostimulatory properties that can contribute to the generation of anti-cancer immune responses. Treatment with radiation can induce a variety of pro-...
It is time to accelerate building local vaccine adjuvant manufacturing capacity [0.03%]
是时候加快在当地建立疫苗佐剂制造能力了
Christopher B Fox
Christopher B Fox