Seasonal influenza vaccination: knowledge, attitude and practice in Varna, Bulgaria [0.03%]
保加利亚瓦尔纳市季节性流感疫苗的知识、态度和实践状况调查报告
Neli M Ermenlieva,Gabriela S Tsankova,Tatina T Todorova
Neli M Ermenlieva
Background: Seasonal influenza vaccination is recommended for certain at-risk groups in Bulgaria, but vaccine coverage and the population's perception of vaccination are currently unknown. The objective of this study was ...
Identification of goals and barriers to treatment from 92 consecutive consultations with families considering peanut oral immunotherapy [0.03%]
连续性咨询报告：探讨花生口服免疫疗法所面临的治疗目标及障碍（共92例患者）
Andrea C Blackman,Aikaterini Anagnostou
Andrea C Blackman
Background: Peanut allergy has become an important public health issue. It can be the cause of severe reactions and also the trigger of significant anxiety for the allergic individual, especially with regards to the risk ...
Therapeutic vaccination immunomodulation: forming the basis of all cancer immunotherapy [0.03%]
治疗性癌症疫苗免疫调节：所有癌症免疫治疗的基础形成
Brendon J Coventry
Brendon J Coventry
Recent immunotherapy advances have convincingly demonstrated complete tumour removal with long-term survival. These impressive clinical responses have rekindled enthusiasm towards immunotherapy and tumour antigen vaccination providing 'cure...
Ivette A Nuñez,Ted M Ross
Ivette A Nuñez
Highly pathogenic avian influenza viruses (HPAIVs), originating from the A/goose/Guangdong/1/1996 H5 subtype, naturally circulate in wild-bird populations, particularly waterfowl, and often spill over to infect domestic poultry. Occasionall...
Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations [0.03%]
流感疫苗在老年人、儿童和孕妇中负担、效力和安全性的评估
Sheena G Sullivan,Olivia H Price,Annette K Regan
Sheena G Sullivan
Vaccination is the most practical means available for preventing influenza. Influenza vaccines require frequent updates to keep pace with antigenic drift of the virus, and the effectiveness, and sometimes the safety, of the vaccine can ther...
Cancer stem cell mobilization and therapeutic targeting of the 5T4 oncofetal antigen [0.03%]
癌干细胞动员及5T4胎源性抗原治疗靶向作用研究进展
Richard Harrop,Eric O&#x;Neill,Peter L Stern
Richard Harrop
Cancer stem cells (CSCs) can act as the cellular drivers of tumors harnessing stem cell properties that contribute to tumorigenesis either as founder elements or by the gain of stem cell traits by the malignant cells. Thus, CSCs can self-re...
The failure of radical treatments to cure cancer: can less deliver more? [0.03%]
激进疗法抗癌失败：少一点是否意味着多一点？
Angus G Dalgleish,Peter L Stern
Angus G Dalgleish
All too often attempts to deliver improved cancer cure rates by increasing the dose of a particular treatment are not successful enough to justify the accompanying increase in toxicity and reduction in quality of life suffered by a signific...
Rajesh Kumar,Huma Qureshi,Suprit Deshpande et al.
Rajesh Kumar et al.
Antibodies that naturally develop in some individuals infected with human immunodeficiency virus 1 (HIV-1) and are capable of broadly neutralizing diverse strains of HIV-1 are useful for two applications: they can inform the rational design...
Optimal use of meningococcal serogroup B vaccines: moving beyond outbreak control [0.03%]
脑膜炎球菌B型疫苗的最适应用：超越疫情控制阶段
Paul Balmer,Laura J York
Paul Balmer
Neisseria meningitidis is a major cause of meningitis and septicemia globally. Vaccines directed against N. meningitidis serogroup B (MenB) have been used to control sporadic and sustained disease in industrialized and non-industrialized co...
Victoria A Brentville,Suha Atabani,Katherine Cook et al.
Victoria A Brentville et al.
The interplay between tumours and the immune system has long been known to involve complex interactions between tumour cells, immune cells and the tumour microenvironment. The progress of checkpoint inhibitors in the clinic in the last deca...