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ISSN:2567-3459

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Sabine F B van der Horst,Tim A C de Vries,Gordon Chu et al. Sabine F B van der Horst et al.
Background For most patients with newly diagnosed atrial fibrillation (AF), direct oral anticoagulants (DOACs) are preferred over vitamin K antagonists. However, there is concern that the lack of monitoring may impair therapy adherence and ...
Gabriel Alejandro Zúñiga,Pranav Kandula,Hardy Sandefur et al. Gabriel Alejandro Zúñiga et al.
Despite anticoagulation recommendations, patients may present with recurrent events. While medication adherence is always a concern, assessment of anticoagulation failure demands a systematic approach, taking into account the potential limi...
Christina Köhler,Luise Tittl,Ulrike Hänsel et al. Christina Köhler et al.
Background Edoxaban is a non-vitamin K dependent oral anticoagulant (NOAC) licensed for venous thromboembolism (VTE) treatment or stroke prevention in atrial fibrillation. Major surgical procedures are not uncommon in anticoagulated patient...
Dana Meknas,Sigrid K Brækkan,John-Bjarne Hansen et al. Dana Meknas et al.
Background Surgery is a major transient risk factor for venous thromboembolism (VTE). However, the impact of major surgery as a VTE trigger has been scarcely investigated using a case-crossover design. Aim To investigate the role of major s...
Judith J de Vries,Chantal Visser,Maureen van Ommen et al. Judith J de Vries et al.
Background Fibrinogen variants as a result of alternative messenger RNA splicing or protein degradation can affect fibrin(ogen) functions. The levels of these variants might be altered during coronavirus disease 2019 (COVID-19), potentially...
Joseph R Shaw,Ubabuko Unachukwu,Joseph Cyr et al. Joseph R Shaw et al.
Background Direct factor Xa inhibitors (FXaIs) account for most oral anticoagulant use and FXaI-associated bleeding events are common. Clinicians have variable national and regional access to specific FXaI reversal agents such as andexanet ...