Risk of Bleeding and Venous Thromboembolism after Colorectal Cancer Surgery in Patients with and without Type 2 Diabetes: A Danish Cohort Study [0.03%]
2型糖尿病患者和非糖尿病患者的结直肠癌术后出血和静脉血栓栓塞风险：一项丹麦队列研究
Frederik Pagh Bredahl Kristensen,Erzsébet Horváth-Puhó,Szimonetta Komjáthiné Szépligeti et al.
Frederik Pagh Bredahl Kristensen et al.
Background Bleeding and venous thromboembolism (VTE) are adverse outcomes after colorectal cancer (CRC) surgery. Type 2 diabetes (T2D) clusters with bleeding and VTE risk factors. We examined the bleeding and VTE risk in patients with T2D u...
Safety and Efficacy of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Untreated Patients with Hemophilia B [0.03%]
重组凝血因子Ⅸ与白蛋白融合蛋白(rIX-FP)治疗从未接受过凝血因子Ⅸ治疗的B型血友病患者的疗效和安全性
Richard Lemons,Michael Wang,Julie Curtin et al.
Richard Lemons et al.
Introduction Recombinant fusion protein linking coagulation factor IX (FIX) with albumin (rIX-FP) has been shown to be an effective, well-tolerated treatment for patients with severe hemophilia B who had previously received factor replaceme...
Real-world Data on Treatment Patterns and Bleeding in Cancer-associated Thrombosis: Data from the TROLL Registry [0.03%]
TROLL登记处癌症相关血栓治疗模式和出血的现实世界数据
Zygimantas Zaboras,Camilla Tøvik Jørgensen,Andreas Stensvold et al.
Zygimantas Zaboras et al.
Background International guidelines are increasingly recommending direct oral anticoagulants (DOACs) as the first-line treatment for cancer-associated thrombosis (CAT). However, data regarding treatment patterns and adherence to guidelines ...
Bleeding Risk Prediction in Patients Treated with Antithrombotic Drugs According to the Anatomic Site of Bleeding, Indication for Treatment, and Time Since Treatment Initiation [0.03%]
抗凝治疗患者的出血风险预测模型——根据出血部位、适应症和起始治疗时间区分
Vinai Bhagirath,Tanya Kovalova,Jia Wang et al.
Vinai Bhagirath et al.
Background Reasons for the relatively poor performance of bleeding prediction models are not well understood but may relate to differences in predictors for various anatomical sites of bleeding. Methods We pooled individual participant data...
Anticoagulation Stewardship to Bridge the Implementation Gap in Perioperative Anticoagulation Management [0.03%]
围手术期抗凝管理中抗菌药物 stewardship 治理模式在缩小实施差距中的作用
Alfonso J Tafur,Geoffrey D Barnes,Vinai C Bhagirath et al.
Alfonso J Tafur et al.
Lack of alignment of care protocols among providers in health care is a driver of increased costs and suboptimal patient outcomes. Perioperative anticoagulation management is a good example of a complex area where protocol creation is a cli...
Development of the Integrated Computer Simulation Model of the Intracellular, Transmembrane, and Extracellular Domain of Platelet Integrin α IIb β 3 (Platelet Membrane Glycoprotein: GPIIb-IIIa) [0.03%]
血小板整合素α IIb β 3（血小板膜糖蛋白：GPIIb-IIIa）的细胞内、跨膜和细胞外域的综合计算机模拟模型的发展
Masamitsu Nakayama,Shinichi Goto,Shinya Goto
Masamitsu Nakayama
Background The structure and functions of the extracellular domain of platelet integrin α IIb β 3 (platelet membrane glycoprotein: GPIIb-IIIa) change substantially upon platelet activation. However, the stability of the integrated model o...
Risk Profiles and Treatment Patterns in Atrial Fibrillation Patients with Chronic Kidney Disease Receiving or not Receiving Anticoagulation Therapy [0.03%]
伴有慢性肾病的房颤患者抗凝治疗的风险特征及治疗模式分析
Reinhold Kreutz,Gilbert Deray,Jürgen Floege et al.
Reinhold Kreutz et al.
Background Patients with atrial fibrillation (AF) and chronic kidney disease (CKD) are at high risk for both thromboembolism and bleeding events. The latter induces a potential reason for withholding oral anticoagulation (OAC) despite an in...
Transient Perivascular Inflammation of the Carotid Artery as a Poorly Recognized Cause of Neck Pain [0.03%]
颈痛的少见原因——颈动脉瞬时管周炎症
Sophie Greutert,Tatiana Schlomer,Marc Righini
Sophie Greutert
Transient perivascular inflammation of the carotid artery (TIPIC) syndrome, historically named idiopathic carotidynia or Fay syndrome, is a rare condition characterized by inflammation and pain in the carotid artery. The diagnosis requires ...
Unraveling Epigenetic Interplay between Inflammation, Thrombosis, and Immune-Related Disorders through a Network Meta-analysis [0.03%]
通过网络荟萃分析揭示炎症、血栓形成和免疫相关疾病之间的表观遗传相互作用
Shankar Chanchal,Swati Sharma,Syed Mohd et al.
Shankar Chanchal et al.
Inflammation and thrombosis are two distinct yet interdependent physiological processes. The inflammation results in the activation of the coagulation system that directs the immune system and its activation, resulting in the initiation of ...
Treatment Patterns of Cancer-associated Thrombosis in the Netherlands: The Four Cities Study [0.03%]
荷兰癌症相关性血栓的治疗模式：四个城市的研究
Fleur H J Kaptein,Noori A M Guman,Susan B Lohle et al.
Fleur H J Kaptein et al.
Background Current guidelines recommend either low-molecular weight heparin (LMWH) or direct oral anticoagulants (DOACs) as first-line treatment in cancer-associated venous thromboembolism (VTE). Aim This study aimed to investigate treatmen...