Anticoagulation Stewardship to Bridge the Implementation Gap in Perioperative Anticoagulation Management [0.03%]
围手术期抗凝管理中抗菌药物 stewardship 治理模式在缩小实施差距中的作用
Alfonso J Tafur,Geoffrey D Barnes,Vinai C Bhagirath et al.
Alfonso J Tafur et al.
Lack of alignment of care protocols among providers in health care is a driver of increased costs and suboptimal patient outcomes. Perioperative anticoagulation management is a good example of a complex area where protocol creation is a cli...
Development of the Integrated Computer Simulation Model of the Intracellular, Transmembrane, and Extracellular Domain of Platelet Integrin α IIb β 3 (Platelet Membrane Glycoprotein: GPIIb-IIIa) [0.03%]
血小板整合素α IIb β 3（血小板膜糖蛋白：GPIIb-IIIa）的细胞内、跨膜和细胞外域的综合计算机模拟模型的发展
Masamitsu Nakayama,Shinichi Goto,Shinya Goto
Masamitsu Nakayama
Background The structure and functions of the extracellular domain of platelet integrin α IIb β 3 (platelet membrane glycoprotein: GPIIb-IIIa) change substantially upon platelet activation. However, the stability of the integrated model o...
Risk Profiles and Treatment Patterns in Atrial Fibrillation Patients with Chronic Kidney Disease Receiving or not Receiving Anticoagulation Therapy [0.03%]
伴有慢性肾病的房颤患者抗凝治疗的风险特征及治疗模式分析
Reinhold Kreutz,Gilbert Deray,Jürgen Floege et al.
Reinhold Kreutz et al.
Background Patients with atrial fibrillation (AF) and chronic kidney disease (CKD) are at high risk for both thromboembolism and bleeding events. The latter induces a potential reason for withholding oral anticoagulation (OAC) despite an in...
Transient Perivascular Inflammation of the Carotid Artery as a Poorly Recognized Cause of Neck Pain [0.03%]
颈痛的少见原因——颈动脉瞬时管周炎症
Sophie Greutert,Tatiana Schlomer,Marc Righini
Sophie Greutert
Transient perivascular inflammation of the carotid artery (TIPIC) syndrome, historically named idiopathic carotidynia or Fay syndrome, is a rare condition characterized by inflammation and pain in the carotid artery. The diagnosis requires ...
Unraveling Epigenetic Interplay between Inflammation, Thrombosis, and Immune-Related Disorders through a Network Meta-analysis [0.03%]
通过网络荟萃分析揭示炎症、血栓形成和免疫相关疾病之间的表观遗传相互作用
Shankar Chanchal,Swati Sharma,Syed Mohd et al.
Shankar Chanchal et al.
Inflammation and thrombosis are two distinct yet interdependent physiological processes. The inflammation results in the activation of the coagulation system that directs the immune system and its activation, resulting in the initiation of ...
Treatment Patterns of Cancer-associated Thrombosis in the Netherlands: The Four Cities Study [0.03%]
荷兰癌症相关性血栓的治疗模式：四个城市的研究
Fleur H J Kaptein,Noori A M Guman,Susan B Lohle et al.
Fleur H J Kaptein et al.
Background Current guidelines recommend either low-molecular weight heparin (LMWH) or direct oral anticoagulants (DOACs) as first-line treatment in cancer-associated venous thromboembolism (VTE). Aim This study aimed to investigate treatmen...
Effect of Plasma Fibrinogen Levels on the Risk of Stroke in Patients with Type 2 Diabetes: A Systematic Review [0.03%]
血浆纤维蛋白原水平对2型糖尿病患者卒中风险的影响：系统性评价
Nicoline Daugaard,Else-Marie Bladbjerg,Moniek P M de Maat et al.
Nicoline Daugaard et al.
Aims In this systematic review, we assessed the literature on the association between fibrinogen levels and stroke in patients with type 2 diabetes (T2D). Methods MEDLINE and Ovid searches of English reports were performed on the relation b...
Surgical Experience from the STASEY Study of Emicizumab Prophylaxis in People with Hemophilia A with Factor VIII Inhibitors [0.03%]
STASEY研究中Emicizumab预防治疗伴第八因子抑制物的A型血友病患者的外科经验
Giancarlo Castaman,Flora Peyvandi,Johanna A Kremer Hovinga et al.
Giancarlo Castaman et al.
Background Guidelines surrounding emicizumab prophylaxis and perioperative treatment for people with hemophilia A (PwHA) with factor (F)VIII inhibitors undergoing surgeries are limited. The phase IIIb multicenter, single-arm STASEY study ev...
The Use of Risk Scores for Thromboprophylaxis in Medically Ill Patients-Rationale and Design of the RICO trial [0.03%]
风险评分在内科疾病患者抗凝治疗中的应用 - RICO试验的原理与设计
Francesco Dentali,Mauro Campanini,Aldo Bonaventura et al.
Francesco Dentali et al.
Background Venous thromboembolism (VTE) in hospitalized medically ill patients is a significant cause of morbidity and mortality. Guidelines suggest that VTE and bleeding risk assessment models (RAMs) should be integrated into the clinical ...
Direct-Acting Oral Anticoagulants in patients at extremes of body weight: a review of pharmacological considerations and clinical implications [0.03%]
极体重患者中的直接口服抗凝药：药物因素和临床意义综述
Rosa Talerico,Roberto Pola,Frederikus Albertus Klok et al.
Rosa Talerico et al.
Patients at extremes of body weight are underrepresented in randomized controlled trials of direct-acting oral anticoagulants (DOACs). Therefore, their optimal anticoagulant treatment remains a topic of debate. The aim of this narrative rev...