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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Anouk Gentier,Mueez Aizaz,Maurice Halder et al. Anouk Gentier et al.
Vascular calcification is a common phenomenon in various vascular diseases, where its presence heralds increased occurrence of adverse disease events, which invariably lead to increased morbidity and mortality in patients. Although the impa...
Julia Martinez-Sanchez,Sergi Torramade-Moix,Ana Belén Moreno-Castaño et al. Julia Martinez-Sanchez et al.
Background Association between global platelet function and the risk of venous thromboembolic disease (VTE) has been proposed, though the mechanisms do not involve increased platelet aggregation. However, platelet adhesiveness has not been ...
Isabelle Gouin-Thibault,Alexandre Mansour,Michael Hardy et al. Isabelle Gouin-Thibault et al.
Nowadays, unfractionated heparin (UFH) use is limited to selected patient groups at high risk of both bleeding and thrombosis (patients in cardiac surgery, in intensive care unit, and patients with severe renal impairment), rendering its ma...
Vinita Bahl,Marc J Moote,Hsou Mei Hu et al. Vinita Bahl et al.
Background Venous thromboembolism (VTE) causes significant preventable morbidity and mortality in hospitalized patients. Assessing VTE risk is essential to initiating appropriate prophylaxis and reducing VTE outcomes. Studies show that comp...
Valérie L B I Jansen,Dagmar J M van Mourik,Mark Davids et al. Valérie L B I Jansen et al.
Background The origin of autoantibodies in patients with antiphospholipid syndrome (APS) is unknown. The gut microbiome contributes to autoimmunity and contains peptide homologues to the main APS autoantigen, which affect disease activity i...
Holger Seidel,Melina Duncklenberg,Hans-Jörg Hertfelder et al. Holger Seidel et al.
Background During pregnancy, a physiological increase of molecular activation markers (MAM) of hemostasis such as prothrombin fragments 1 + 2, thrombin-antithrombin complex, and D-dimers (DD) occurs. Therefore, monitoring MAM levels during ...
Cindy M M de Jong,Lisette F van Dam,Charlotte E A Dronkers et al. Cindy M M de Jong et al.
Background The noninvasive magnetic resonance direct thrombus imaging (MRDTI) technique can be used to diagnose acute deep vein thrombosis (DVT), without the use of intravenous contrast. MRDTI holds the potential to differentiate between ac...
Tomás J González-López,Gabriela Alperovich,Elena Burillo et al. Tomás J González-López et al.
Background Immune thrombocytopenia (ITP) is characterised by low platelet counts and often leads to bleeding, fatigue, and reduced health-related quality of life. Methods This observational, retrospective, population-based study using BIG-P...
Bülent Zülfikar,Johnny Mahlangu,Salim Mohamed Nekkal et al. Bülent Zülfikar et al.
Background Activated prothrombin complex concentrate (aPCC) is indicated for bleed treatment and prevention in patients with hemophilia with inhibitors. The safety and tolerability of intravenous aPCC at a reduced volume and faster infusion...