Management of Urgent Bleeding in Patients with Hemophilia A: Focus on the Use of Emicizumab [0.03%]
甲型血友病患者紧急出血的管理：emicizumab的应用聚焦
Víctor Jiménez-Yuste,María T Álvarez-Román,Rubén Berrueco et al.
Víctor Jiménez-Yuste et al.
Management of patients with hemophilia A (HA) requires the knowledge and experience of specialized health care professionals. However, these patients may need to be attended in emergencies, outside the referral hospital, where health care p...
Age-Dependent Detection of Atrial Fibrillation with Implantable Cardiac Monitors in Patients with Cryptogenic Stroke [0.03%]
不明原因卒中的植入式心脏监测仪在不同年龄段的心房颤动检出率
Tobias Uhe,Janina Keilitz,Jörg Berrouschot et al.
Tobias Uhe et al.
Background Continuous monitoring using implantable cardiac monitors (ICMs) results in atrial fibrillation (AF) detection rates of up to 30% in patients with cryptogenic stroke (CS). Although higher age is an independent risk factor for AF, ...
Disease Burden, Clinical Outcomes, and Quality of Life in People with Hemophilia A without Inhibitors in Europe: Analyses from CHESS II/CHESS PAEDs [0.03%]
CHESS II/CHESS PAEDs研究中的甲型血友病（无抑制物）患者的疾病负担、临床结局和生活质量分析
Pratima Chowdary,Richard Ofori-Asenso,Francis Nissen et al.
Pratima Chowdary et al.
Introduction Limited data relating to treatment burden, quality of life, and mental health burden of hemophilia A (HA) are currently available. Aim To provide a comprehensive overview of unmet needs in people with HA (PwHA) using data gener...
Thrombophilia Testing: from Genetic Predisposition to Discrimination [0.03%]
血栓形成倾向的检验：从基因易感性到区别对待政策
Andreas Verstraete,Kathleen Freson,Peter Verhamme et al.
Andreas Verstraete et al.
Challenges in the Monitoring of Therapeutic Plasma Exchange during Acute Heparin-Induced Thrombocytopenia in Adults under ECMO [0.03%]
成人体外膜氧合(ECMO)支持下的他莫西林诱导的血小板减少症(HTP)急性期治疗性血浆置换监测挑战
Nicolas Gendron,Candice Cavalie,Elie Kantor et al.
Nicolas Gendron et al.
Therapeutic plasma exchange (TPE) has been proposed to remove heparin-induced thrombocytopenia (HIT) antibodies before planned thoracic surgery in patients with acute HIT and to allow brief re-exposure to heparin during surgery. In patients...
Impaired Whole-Blood Fibrinolysis is a Predictor of Mortality in Intensive Care Patients [0.03%]
重症监护患者的全血纤溶功能受损是死亡率的预测指标
Julie S Brewer,Christine L Hvas,Anne-Mette Hvas et al.
Julie S Brewer et al.
Background Altered fibrinolysis is considered to play a crucial role in the development of coagulopathy in sepsis. However, routine laboratory tests for fibrinolysis are currently very limited, and the impact of fibrinolytic capacity on cli...
Risk of Bleeding and Venous Thromboembolism after Colorectal Cancer Surgery in Patients with and without Type 2 Diabetes: A Danish Cohort Study [0.03%]
2型糖尿病患者和非糖尿病患者的结直肠癌术后出血和静脉血栓栓塞风险：一项丹麦队列研究
Frederik Pagh Bredahl Kristensen,Erzsébet Horváth-Puhó,Szimonetta Komjáthiné Szépligeti et al.
Frederik Pagh Bredahl Kristensen et al.
Background Bleeding and venous thromboembolism (VTE) are adverse outcomes after colorectal cancer (CRC) surgery. Type 2 diabetes (T2D) clusters with bleeding and VTE risk factors. We examined the bleeding and VTE risk in patients with T2D u...
Safety and Efficacy of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Untreated Patients with Hemophilia B [0.03%]
重组凝血因子Ⅸ与白蛋白融合蛋白(rIX-FP)治疗从未接受过凝血因子Ⅸ治疗的B型血友病患者的疗效和安全性
Richard Lemons,Michael Wang,Julie Curtin et al.
Richard Lemons et al.
Introduction Recombinant fusion protein linking coagulation factor IX (FIX) with albumin (rIX-FP) has been shown to be an effective, well-tolerated treatment for patients with severe hemophilia B who had previously received factor replaceme...
Real-world Data on Treatment Patterns and Bleeding in Cancer-associated Thrombosis: Data from the TROLL Registry [0.03%]
TROLL登记处癌症相关血栓治疗模式和出血的现实世界数据
Zygimantas Zaboras,Camilla Tøvik Jørgensen,Andreas Stensvold et al.
Zygimantas Zaboras et al.
Background International guidelines are increasingly recommending direct oral anticoagulants (DOACs) as the first-line treatment for cancer-associated thrombosis (CAT). However, data regarding treatment patterns and adherence to guidelines ...
Bleeding Risk Prediction in Patients Treated with Antithrombotic Drugs According to the Anatomic Site of Bleeding, Indication for Treatment, and Time Since Treatment Initiation [0.03%]
抗凝治疗患者的出血风险预测模型——根据出血部位、适应症和起始治疗时间区分
Vinai Bhagirath,Tanya Kovalova,Jia Wang et al.
Vinai Bhagirath et al.
Background Reasons for the relatively poor performance of bleeding prediction models are not well understood but may relate to differences in predictors for various anatomical sites of bleeding. Methods We pooled individual participant data...