Association of Fibrin Clot Characteristics with Development of Ischemic Stroke in Patients with Recently Diagnosed Type 2 Diabetes [0.03%]
糖尿病患者缺血性卒中的发病与纤维蛋白凝块特征之间的关联
Nicoline Daugaard,Else-Marie Bladbjerg,Helene M L Svane et al.
Nicoline Daugaard et al.
Background: Ischemic stroke occurs when a thrombus blocks a cerebral artery, and an important component is the fibrin clot. Different plasma fibrinogen variants have been associated with stroke risk in type 2 diabetes (T2...
Diabetes, Protein Misfolding, and Heat Stress: Molecular Insights and Translational Perspectives [0.03%]
糖尿病、蛋白质错误折叠与热激：分子洞察及转化视角
M Marc Abreu,Victor Hugo Spitz,David M Smadja
M Marc Abreu
Diabetes mellitus (DM), particularly type 1 (T1D) and type 2 (T2D), is a growing global health burden with complex pathophysiology extending beyond glucose dysregulation. Both forms of diabetes involve cellular stress, chronic inflammation,...
Reduced- Compared with Standard-Dose Direct Oral Anticoagulant for Extended Treatment of Venous Thromboembolism: A Systematic Review and Meta-Analysis [0.03%]
低剂量与标准剂量直接口服抗凝药用于延长治疗静脉血栓栓塞的疗效比较：系统评价和.meta.分析
Carmen Ka Man Cheung,Stephanie Carlin,Thomas C Scheier et al.
Carmen Ka Man Cheung et al.
Introduction: Reduced-dose direct oral anticoagulants (DOACs) may provide similar efficacy with less bleeding than standard dose for extended venous thromboembolism (VTE) treatment. It is unclear whether standard doses ar...
David Gimelfarb,Atefeh Ghorbanzadeh,Alfonso J Tafur
David Gimelfarb
Paediatric Subanalysis of TSUBASA, Assessing Physical Activity, Bleeding, Quality of Life and Safety in People with Haemophilia A Receiving Emicizumab [0.03%]
佩乐能TSUBASA儿科亚组分析：在甲型血友病合并抑制物患者中评估emicizumab治疗对身体活动、出血及生活质量的影响和安全性
Keiji Nogami,Kagehiro Amano,Akihiro Sawada et al.
Keiji Nogami et al.
Introduction: Limited data are available on the relationship between bleeding outcomes and physical activity, and the quality of daily life (QoL), in children with haemophilia A (HA) receiving emicizumab prophylaxis. ...
Differences and Compatibility between Human and Porcine Fibrinolytic Components toward Plasmin Generation and Fibrin Degradation [0.03%]
人和猪溶栓成分的差异及在生成尿激酶原和溶解纤维蛋白方面的兼容性
Paul Y Kim,Chengliang Wu,Hena Noorzada et al.
Paul Y Kim et al.
Background: Fibrinolysis is the process of blood clot breakdown by the enzyme plasmin. Despite increased usage of large animals such as pigs to study fibrinolysis in human disease models, a comprehensive study comparing t...
Anticoagulant Therapy in Neonatal Acute Infectious Peritonitis Based on the TAT, PIC, t-PAIC, and sTM: A New Case Series [0.03%]
基于TAT、PIC、t-PAIC和sTM的新生儿急性感染性腹膜炎抗凝治疗：新的病例系列
Wenya Wang,Yue Gao,Yan Qiao et al.
Wenya Wang et al.
Neonatal acute peritonitis is a leading cause of morbidity and mortality and poses challenges that demand prompt diagnosis and treatment, particularly in infants with disseminated intravascular coagulation. Here, we report a case series of ...
Bleeding Risk of Central Venous Catheterization in Adults: A Systematic Review and Meta-analysis [0.03%]
成人中心静脉置管出血风险的系统评价和 meta 分析
Nicola Mumoli,Lucia Colavolpe,Piero Tarantini et al.
Nicola Mumoli et al.
Background: Central venous catheter (CVC) insertion is a cornerstone procedure in hospitalized and critically ill adults. However, many patients requiring CVCs have coagulopathy, thrombocytopenia, liver disease, or hemato...
Identification of Prothrombin Belgrade Variant in a Mexican-American Family with Recurrent Deep Vein Thrombosis [0.03%]
在具有复发性深静脉血栓形成病史的墨西哥美国人家庭中鉴定出贝尔格莱德型凝血酶原变异型
Émile Moura Coelho da Silva,Natalie Montanez,Miguel Escobar
Émile Moura Coelho da Silva
A rare prothrombin variant (c.1787G > A, p.Arg596Gln), also known as the prothrombin Belgrade variant, has been associated with an increased predisposition to thrombosis through resistance to antithrombin. This variant has been previously r...
Edoxaban Overdose in a Child: Unexpected Observation of Clot Lysis [0.03%]
儿童艾-do-xa-班过量事件中意外发现血栓溶解现象
Mouna Sassi,Emna Sfar,Linda Khefacha et al.
Mouna Sassi et al.