National Early Warning Score for Predicting Clinical Outcome of Acute Pulmonary Embolism in Intermediate-High Risk Patients [0.03%]
用于中高危急性肺栓塞患者的预后评估及临床转归的预警评分系统研究
Audrey J C Overgaauw,Esther J Nossent,Lilian J Meijboom et al.
Audrey J C Overgaauw et al.
Background: Although the European Society of Cardiology (ESC) predicts mortality in acute pulmonary embolism (PE), it may overtriage the level of clinical monitoring needed. The National Early Warning Score (NEWS) is used...
Fibrinolytic Capacity and Risk of Bleeding in Intensive Care Patients with Acute Kidney Injury [0.03%]
急性肾损伤重症监护患者的溶栓能力和出血风险
Rasmus R Mikkelsen,Christine L Hvas,Tua Gyldenholm et al.
Rasmus R Mikkelsen et al.
Background: Acute kidney injury (AKI) is common among intensive care unit (ICU) patients and is associated with increased bleeding risk. The impact of fibrinolysis in AKI-related bleeding has not been explored previously....
Association between Active Cancer and Risk of Thrombotic and Cardiovascular Outcomes in Outpatients with COVID-19: A CORONA-VTE Network Analysis [0.03%]
基于CORONA-VTE网络的分析：癌症与冠状病毒病(COVID-19)门诊患者血栓和心血管结局风险的关系：一项队列研究
Bridget McGonagle,Christie Greason,Darsiya Krishnathasan et al.
Bridget McGonagle et al.
Coronavirus disease 2019 (COVID-19) and active cancer are each independently associated with excess risk of thrombotic and cardiovascular events. However, data are limited regarding the risk of these events in outpatients with active cancer...
Daniel Kraemmer,Rafaela Vostatek,Marina Trappl et al.
Daniel Kraemmer et al.
Introduction: Hemophilia is a rare X-linked bleeding disorder leading to recurrent hemarthroses, hemophilic arthropathy, and impaired quality of life. A chronic lifelong disease, hemophilia might be associated with accele...
Mental Health, Work Productivity, and Quality of Life in People with Severe Haemophilia A Receiving Prophylaxis: Findings from the CHESS Data Platform [0.03%]
CHESS数据平台中重度甲型血友病患者心理健康、工作能力和生活质量的研究
Pratima Chowdary,Letizia Polito,Mark Oellerich et al.
Pratima Chowdary et al.
Background: Newer therapeutic options for people with severe haemophilia A (PwSHA), in addition to improved clinical and patient-reported outcomes (PROs), have offered more personalised treatment regimens. This analysis e...
A Contemporary Review of Plasminogen Activator Inhibitor Type 1: Structure, Function, Genetic Architecture, and Intracellular/Extracellular Roles [0.03%]
纤溶酶原激活物抑制剂-1的当代综述：结构、功能、遗传构成和胞内/胞外作用
Jacob Wortley,Justin Vu,Neha Soogoor et al.
Jacob Wortley et al.
Plasminogen activator inhibitor type 1 (PAI-1) is the key regulator of the fibrinolytic system, thereby acting as a potent mediator in thrombosis. Plasminogen activators such as PAI-1 mediate the conversion of the inactive zymogen plasminog...
Effects of DOACs on Mouse Melanoma Metastasis and the Inhibitory Mechanism of Edoxaban, a Factor Xa-Specific DOAC [0.03%]
DOAC对小鼠黑色素瘤转移的影响及达比加群酯的特异性抑制机制研究
Keiichi Hiramoto,Taisei Watanabe,Masashi Imai et al.
Keiichi Hiramoto et al.
Introduction: Direct oral anticoagulants (DOACs) have been widely used in patients with thromboembolism. We previously reported that among DOACs, edoxaban (EDX), a factor Xa (FXa)-specific DOAC, most effectively inhibited...
Andreas Verstraete,Nicholas Cauwenberghs,Shayan Calhori et al.
Andreas Verstraete et al.
Background: Venous thromboembolism (VTE) is a significant contributor to global morbidity and mortality. Although management strategies and the distribution of risk factors have evolved, contemporary epidemiologic data ar...
Corrigendum: Prospective, Observational Study of the Clinical Outcomes of FVIII Treatment in Adults and Adolescents with Severe Haemophilia A [0.03%]
FVIII治疗重度HA成人及青少年患者的临床结局观察研究的勘误通知书
Pratima Chowdary,Liane Khoo,Michael Wang et al.
Pratima Chowdary et al.
[This corrects the article DOI: 10.1055/a-2621-9749.]. The Author(s). This is an open access article published by Thieme under the terms of the Creative ...
Platelet RNA-Seq Reveals Genes Associated with Carotid Intima-Media Thickness: A Cross-Sectional Study [0.03%]
基于血小板RNA测序的颈动脉内膜中层厚度相关的基因：横断面研究
Zhanfei Tan,Fan Guo,Jiaming Gao et al.
Zhanfei Tan et al.
Background: Although the association between platelet characteristics and the risk of developing atherosclerosis (AS) has been acknowledged, the specific role of platelets in AS development and progression remains unclear...