Monitoring mepolizumab treatment in chronic rhinosinusitis with nasal polyps (CRSwNP): Discontinue, change, continue therapy? [0.03%]
针对鼻息肉型慢性鼻窦炎患者的美泊利单抗治疗监测：停止、更改还是继续治疗？
Ludger Klimek,Ulrike Förster-Ruhrmann,Heidi Olze et al.
Ludger Klimek et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial inflammatory disease of the mucous membranes of the nose and sinuses. Eosinophilic inflammation is described as a common endotype. The anti...
Christiane Hilger,Bente Janssen-Weets,Kyra Swiontek
Christiane Hilger
Furry pets are beloved companion animals; horse riding is a popular leisure activity. So-called hypoallergenic animals have gained high interest as sensitization to animal dander and allergy to furry animals are widespread. Allergen immunot...
Individual wearable air purifier protects against pollen, house dust mite, and cat allergens: Report from an allergen exposure chamber [0.03%]
个体式空气净化器可有效防护花粉、尘螨和猫过敏原——过敏暴露室实验报告
Karl-Christian Bergmann,Teresa Hartung,Torsten Zuberbier
Karl-Christian Bergmann
Purpose: Evaluation of a new individual wearable air purifier (Respiray Wear A+) for birch pollen, house dust mite (HDM), and cat-allergic rhinoconjunctivitis (ARC) patients in a standardized allergen exposure chamber (AE...
Eosinophil granulocytes in chronic inflammatory respiratory diseases and CRSwNP: Function, immunological basis, and clinical significance [0.03%]
慢性炎症性呼吸道疾病和肉芽肿性鼻窦炎中嗜酸性粒细胞的功能、免疫学基础及临床意义
Felix Klimek,Christoph Bergmann,Jan Hagemann et al.
Felix Klimek et al.
Introduction: Eosinophils play an important regulatory and immunomodulatory role in airway mucosa and have antiparasitic and antiviral properties as well as pro-inflammatory effects that may also cause persistence of infl...
Animal exposure, sensitization, and allergic symptoms in first-year veterinary medicine students [0.03%]
新生兽医专业学生接触、过敏感应及过敏症状情况研究
Eva Zahradnik,Christoph Nöllenheidt,Ingrid Sander et al.
Eva Zahradnik et al.
The AllergoVet study longitudinally examines the influence of animal exposure on the development of sensitization and allergic diseases among veterinary medicine students. In this group, contact to animals usually existed long before the st...
EGPA: Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) as a special presentation of chronic rhinosinusitis with nasal polyps (CRSwNP) [0.03%]
变应性肉芽肿性血管炎（楚格-斯特劳斯综合征）慢性鼻窦炎伴鼻息肉的一种特殊表现型
Jan Hagemann,Martin Laudien,Sven Becker et al.
Jan Hagemann et al.
Introduction: Eosinophilic granulomatosis with polyangiitis (EGPA) was formerly known as Churg-Strauss syndrome. The condition is characterized by disseminated necrotizing vasculitis with extravascular granulomas associat...
J Christian Virchow,Oliver Pfaar,Marek Lommatzsch
J Christian Virchow
Remission is the goal of modern asthma treatment. Allergen immunotherapy (AIT) is an essential component in the armamentarium of personalized asthma therapy. Subcutaneous AIT (SCIT) or sublingual AIT (SLIT) offer the possibility to prevent ...
Marek Lommatzsch
Marek Lommatzsch
The development and approval of DMAADs ("disease-modifying anti-asthmatic drugs"), in particular inhaled steroids (alone or in combination with long-acting bronchodilators), biologics and modern allergen immunotherapies, has fundamentally c...
Role of FEF25-75 in characterizing outpatients with asthma in clinical practice [0.03%]
FEF25-75%在哮喘门诊患者特征描述中的作用
Giorgio Ciprandi,Irene Schiavetti
Giorgio Ciprandi
Background: Asthma is characterized by variable airflow limitation. FEF25-75 has been proposed as a reliable marker for bronchial obstruction, especially when FEV1 and FEV1/FVC are normal. ...
Magdalena Zemelka-Wiacek,Marek Jutel
Magdalena Zemelka-Wiacek
Although used for over 100 years, allergen immunotherapy (AIT) is still an indispensable tool in modern allergy managemen20t due to its potential to cure allergic diseases. Its current rapid development through the application of personaliz...