Update of the evidence- and consensus-based S3 guideline on atopic dermatitis: Systemic therapy with biologics or Janus kinase inhibitors and specific aspects of systemic therapy in pregnancy and lactation [0.03%]
特应性皮炎证据及共识的S3指南更新：生物制剂或JAK抑制剂系统治疗以及系统治疗在妊娠和哺乳期的特殊问题
Thomas Werfel,Annice Heratizadeh,Matthias Augustin et al.
Thomas Werfel et al.
This guideline is a partial update of the S3 guideline on atopic dermatitis (AWMF register no. 013-027) published in 2023. The chapters on systemic therapy with biologics and Janus kinase inhibitors as well as the chapter on pregnancy, brea...
Resolution of childhood wheat allergy through evolution into WALDA? A case report [0.03%]
儿童小麦过敏经WALDA演变而消失的病例报告
Charlotte J Kiani,Valentina Faihs,Claudia Kugler et al.
Charlotte J Kiani et al.
Background: Wheat allergy may present with different phenotypes. Childhood-onset wheat allergy is characterized by immediate-type IgE-mediated reactions to wheat ingestion alone. It typically affects atopic individuals an...
Case Reports
Allergologie select. 2026 Jun 16:10:114-119. DOI:10.5414/ALX02631E 2026
Phila Cara Baumann,Lennart Matthias Roesner
Phila Cara Baumann
This review provides an overview of recent advances in understanding T-cell inflammation in atopic dermatitis (AD), a common chronic inflammatory skin disease. After recognizing their cognate antigen in the acute phase of the disease, the h...
Cefazolin as an alternative in patients with a history of penicillin or β-lactam antibiotic allergy: A case overview [0.03%]
青霉素或β-内酰胺类抗生素过敏患者的替代药物：头孢唑林——个例综述
Burkhard Kreft,Johannes Wohlrab,Cord Sunderkötter
Burkhard Kreft
Many patients with suspected or confirmed allergy to penicillin or β-lactam antibiotics are unnecessarily denied all β-lactam antibiotics (BLA) and instead given a less effective antibiotic with more side effects. However, cefazolin, a fi...
Case Reports
Allergologie select. 2026 May 29:10:101-106. DOI:10.5414/ALX02634E 2026
Does the teicoplanin skin test predict IgE-mediated hypersensitivity? [0.03%]
teicoplanin皮试能预测IgE介导的过敏反应吗？
Nur Betül Baştuğ İnan,Özge Göktürk,Yavuz Karahan et al.
Nur Betül Baştuğ İnan et al.
Various delayed-type hypersensitivity reactions have been reported following teicoplanin administration, including drug rash with eosinophilia and systemic symptoms (DRESS syndrome), and acute generalized exanthematous pustulosis (AGEP). Un...
Case Reports
Allergologie select. 2026 May 21:10:98-100. DOI:10.5414/ALX02632E 2026
Expert consensus on the long-term use of lanadelumab in hereditary angioedema: Toward harmonized care [0.03%]
长效C5补体抑制剂拉那利尤单抗治疗遗传性血管性水肿的长期应用专家共识：迈向规范化治疗
Emel Aygören-Pürsün,Jens Greve,Inmaculada Martinez-Saguer et al.
Emel Aygören-Pürsün et al.
Background: Hereditary angioedema (HAE) is a rare, potentially life-threatening disease caused in most cases by C1 inhibitor deficiency. Lanadelumab, a monoclonal antibody targeting plasma kallikrein, is an effective long...
Prick tests and basophil activation tests in hypersensitivity to SARS-CoV-2 vaccines and components [0.03%]
SARS-CoV-2疫苗和成分过敏的皮内试验和嗜碱性粒细胞活化试验
Anna-Emilia Aust,Heidi Reh,Bettina Wedi
Anna-Emilia Aust
In collaboration with certified allergy centers (CACs) in Germany, a standardized procedure was developed for the allergologic evaluation of hypersensitivity reactions to SARS-CoV-2 vaccines. Our CAC prospectively evaluated 60 subjects with...
Decoding allergy in vitro: Challenges and clinical use of humoral and cellular methods [0.03%]
过敏的体外检测：血清学和细胞学方法的临床应用及挑战
Bettina Wedi,Timo Buhl
Bettina Wedi
In vitro assays are essential tools in diagnosing IgE-mediated allergic diseases and complement clinical history and skin testing across food, inhalant, venom, and drug allergies. This methodological review is intended for clinicians seekin...
The MRGPRX2 paradigm shift: Redefining mast cell activation pathways in chronic urticaria [0.03%]
MRGPRX2的范式转变：重新定义慢性荨麻疹中的肥大细胞活化途径
Kun Wu,Junlin Liu
Kun Wu
Chronic urticaria (CU) is a skin disease characterized by recurrent episodes of vascular dilation and increased permeability of the cutaneous and mucosal microvasculature. Although antihistamines and omalizumab remain first-line and second-...
Kurtuluş Aksu,Onur Telli,Melis Yağdıran et al.
Kurtuluş Aksu et al.
Introduction: Biological agents used in the treatment of rheumatic diseases and malignancies cause an increase in herpes zoster susceptibility. This may also be the case for monoclonal antibody treatments used in asthma b...
Case Reports
Allergologie select. 2026 Apr 17:10:49-51. DOI:10.5414/ALX400616 2026