Real-World Evidence for a Smartwatch-Based Parkinson's Motor Assessment App for Patients Undergoing Therapy Changes [0.03%]
基于智能手表的帕金森病运动评估应用程序在治疗改变时的现实世界证据
Aaron J Hadley,David E Riley,Dustin A Heldman
Aaron J Hadley
Introduction: Parkinson's disease (PD) is poorly quantified by patients outside the clinic, and paper diaries have problems with subjective descriptions and bias. Wearable sensor platforms; however, can accurately quantif...
Developing a Novel Measurement of Sleep in Rheumatoid Arthritis: Study Proposal for Approach and Considerations [0.03%]
在类风湿关节炎中开发一种新型睡眠测量方法的研究提案：研究方法和考虑因素
Michelle Crouthamel,Robert J Mather,Suraj Ramachandran et al.
Michelle Crouthamel et al.
The development of novel digital endpoints (NDEs) using digital health technologies (DHTs) may provide opportunities to transform drug development. It requires a multidisciplinary, multi-study approach with strategic planning and a regulato...
Automatic Identification of Upper Extremity Rehabilitation Exercise Type and Dose Using Body-Worn Sensors and Machine Learning: A Pilot Study [0.03%]
基于身体穿戴传感器和机器学习的上肢康复运动类型和剂量自动识别：一项初步研究
Noah Balestra,Gaurav Sharma,Linda M Riek et al.
Noah Balestra et al.
Background: Prior studies suggest that participation in rehabilitation exercises improves motor function poststroke; however, studies on optimal exercise dose and timing have been limited by the technical challenge of qua...
The Real-World Data Challenges Radar: A Review on the Challenges and Risks regarding the Use of Real-World Data [0.03%]
真实世界数据挑战雷达：关于使用真实世界数据的挑战和风险的回顾性研究
Frank Grimberg,Petra Maria Asprion,Bettina Schneider et al.
Frank Grimberg et al.
Background: The life science industry has a strong interest in real-world data (RWD), a term that is currently being used in many ways and with varying definitions depending on the source. In this review article, we provi...
EVIDENCE Publication Checklist for Studies Evaluating Connected Sensor Technologies: Explanation and Elaboration [0.03%]
连接传感器技术评估出版检查表：解释与说明
Christine Manta,Nikhil Mahadevan,Jessie Bakker et al.
Christine Manta et al.
The EVIDENCE (EValuatIng connecteD sENsor teChnologiEs) checklist was developed by a multidisciplinary group of content experts convened by the Digital Medicine Society, representing the clinical sciences, data management, technology develo...
Adam B Cohen,Brain V Nahed
Adam B Cohen
Digital health has been rapidly thrust into the forefront of care delivery. Poised to extend the clinician's reach, a new set of examination tools will redefine neurologic and neurosurgical care, serving as the basis for the digital neurolo...
Remote Cardiac Safety Monitoring through the Lens of the FDA Biomarker Qualification Evidentiary Criteria Framework: A Case Study Analysis [0.03%]
基于FDA生物标志物认证证据标准框架的远程心脏安全监测案例分析研究
Elena S Izmailova,William A Wood,Qi Liu et al.
Elena S Izmailova et al.
Clinical safety findings remain one of the reasons for attrition of drug candidates during clinical development. Cardiovascular liabilities are not consistently detected in early-stage clinical trials and often become apparent when drugs ar...
Wearable Devices: Current Status and Opportunities in Pain Assessment and Management [0.03%]
可穿戴设备在疼痛评估和管理中的现状及前景
Andrew Leroux,Rachael Rzasa-Lynn,Ciprian Crainiceanu et al.
Andrew Leroux et al.
Introduction: We investigated the possibilities and opportunities for using wearable devices that measure physical activity and physiometric signals in conjunction with ecological momentary assessment (EMA) data to improv...
Voice for Health: The Use of Vocal Biomarkers from Research to Clinical Practice [0.03%]
声健康：从科研到临床实践中的声音生物标志物的应用
Guy Fagherazzi,Aurélie Fischer,Muhannad Ismael et al.
Guy Fagherazzi et al.
Diseases can affect organs such as the heart, lungs, brain, muscles, or vocal folds, which can then alter an individual's voice. Therefore, voice analysis using artificial intelligence opens new opportunities for healthcare. From using voca...
Priya Kumar,Ieuan Clay
Priya Kumar
At the end of 2020, Karger's Digital Biomarkers, together with Evidation Health, produced a special issue entitled "The Future of Digital Health." This brief meeting report provides an overview of the expert panel and workshop that were hel...