Remote Monitoring of Vital and Activity Parameters in Chronic Transfusion-Dependent Patients: A Feasibility Pilot Using Wearable Biosensors [0.03%]
慢性输血依赖患者的远程生命体征和活动参数监测：使用可穿戴生物传感器的可行性试验
Rik Paulus Bernardus Tonino,Mackenzie Tweardy,Stephan Wegerich et al.
Rik Paulus Bernardus Tonino et al.
Introduction: Little is known if, and to what extent, outpatient red blood cell (RBC) transfusions benefit chronic transfusion-dependent patients. Costs, labour, and potential side effects of RBC transfusions cause a rest...
Considerations for Analyzing and Interpreting Data from Biometric Monitoring Technologies in Clinical Trials [0.03%]
在临床试验中分析和解读生物识别监测技术数据的考虑因素
Bohdana Ratitch,Isaac R Rodriguez-Chavez,Abhishek Dabral et al.
Bohdana Ratitch et al.
Background: The proliferation and increasing maturity of biometric monitoring technologies allow clinical investigators to measure the health status of trial participants in a more holistic manner, especially outside of t...
Validation of the Remote Automated ki:e Speech Biomarker for Cognition in Mild Cognitive Impairment: Verification and Validation following DiME V3 Framework [0.03%]
远程自动化ki:e语音生物标志物在轻度认知障碍中对认知的验证：按照DiME V3框架进行验证和确认
Johannes Tröger,Ebru Baykara,Jian Zhao et al.
Johannes Tröger et al.
Introduction: Progressive cognitive decline is the cardinal behavioral symptom in most dementia-causing diseases such as Alzheimer's disease. While most well-established measures for cognition might not fit tomorrow's dec...
Reliability of Automatic Computer Vision-Based Assessment of Orofacial Kinematics for Telehealth Applications [0.03%]
基于计算机视觉的自动评估口颌面部运动学在远程医疗应用中的可靠性
Leif Simmatis,Carolina Barnett,Reeman Marzouqah et al.
Leif Simmatis et al.
Introduction: Telehealth/remote assessment using readily available 2D mobile cameras and deep learning-based analyses is rapidly becoming a viable option for detecting orofacial and speech impairments associated with neur...
Smartphone-Based Gait Cadence to Identify Older Adults with Decreased Functional Capacity [0.03%]
基于智能手机的步态步伐以识别功能下降的老年成人
Daniel S Rubin,Sylvia L Ranjeva,Jacek K Urbanek et al.
Daniel S Rubin et al.
Background: Functional capacity assessment is a critical step in the preoperative evaluation to identify patients at increased risk of cardiac complications and disability after major noncardiac surgery. Smartphones offer...
Objective Home-Monitoring of Physical Activity, Cardiovascular Parameters, and Sleep in Pediatric Obesity [0.03%]
儿童肥胖症的家庭监测：体力活动、心血管参数和睡眠的客观检测
Janine M Knijff,Euphemia C A M Houdijk,Daniëlle C M van der Kaay et al.
Janine M Knijff et al.
Introduction: Clinical research and treatment of childhood obesity is challenging, and objective biomarkers obtained in a home-setting are needed. The aim of this study was to determine the potential of novel digital endp...
Dorsal Finger Fold Recognition by Convolutional Neural Networks for the Detection and Monitoring of Joint Swelling in Patients with Rheumatoid Arthritis [0.03%]
基于卷积神经网络的指褶纹识别在类风湿关节炎患者肿胀关节检测和监测中的应用研究
Thomas Hügle,Leo Caratsch,Matteo Caorsi et al.
Thomas Hügle et al.
Digital biomarkers such as wearables are of increasing interest in monitoring rheumatic diseases, but they usually lack disease specificity. In this study, we apply convolutional neural networks (CNN) to real-world hand photographs in order...
Quantifying the Benefits of Digital Biomarkers and Technology-Based Study Endpoints in Clinical Trials: Project Moneyball [0.03%]
量化数字生物标志物及基于技术的临床试验研究终点的优势：Moneyball项目
Hiromasa Mori,Stig Johan Wiklund,Jason Yuren Zhang
Hiromasa Mori
Introduction: Digital biomarkers have significant potential to transform drug development, but only a few have contributed meaningfully to bring new treatments to market. There are uncertainties in how they will generate ...
Considerations for Conducting Bring Your Own "Device" (BYOD) Clinical Studies [0.03%]
开展“自带设备”（BYOD）临床试验的考量因素
Charmaine Demanuele,Cynthia Lokker,Krishna Jhaveri et al.
Charmaine Demanuele et al.
Background: Digital health technologies are attracting attention as novel tools for data collection in clinical research. They present alternative methods compared to in-clinic data collection, which often yields snapshot...
Video-Based Pose Estimation for Gait Analysis in Stroke Survivors during Clinical Assessments: A Proof-of-Concept Study [0.03%]
基于视频的姿势估计在临床评估中用于卒中患者的步态分析的概念验证研究
Luca Lonini,Yaejin Moon,Kyle Embry et al.
Luca Lonini et al.
Recent advancements in deep learning have produced significant progress in markerless human pose estimation, making it possible to estimate human kinematics from single camera videos without the need for reflective markers and specialized l...