Automated Real-World Video Analysis of Sit-to-Stand Transitions Predicts Parkinson's Disease Severity [0.03%]
自动化的真实世界视频分析坐立过渡预测帕金森病的严重程度
Catherine Morgan,Alessandro Masullo,Majid Mirmehdi et al.
Catherine Morgan et al.
Introduction: Technology holds the potential to track disease progression and response to neuroprotective therapies in Parkinson's disease (PD). The sit-to-stand (STS) transition is a frequently occurring event which is i...
Clinical Validation of Novel Digital Measures: Statistical Methods for Reliability Evaluation [0.03%]
新型数字测量的临床验证：可靠性评价的统计方法
Bohdana Ratitch,Andrew Trigg,Madhurima Majumder et al.
Bohdana Ratitch et al.
Background: Assessment of reliability is one of the key components of the validation process designed to demonstrate that a novel clinical measure assessed by a digital health technology tool is fit-for-purpose in clinica...
Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones [0.03%]
基于人工智能的眼睑下垂测量工具的开发和评估用于成人重症肌无力患者的自拍视频片段录制在智能手机上
Meelis Lootus,Lulu Beatson,Lucas Atwood et al.
Meelis Lootus et al.
Introduction: Myasthenia gravis (MG) is a rare autoimmune disease characterized by muscle weakness and fatigue. Ptosis (eyelid drooping) occurs due to fatigue of the muscles for eyelid elevation and is one symptom widely ...
How Much Evidence Is Enough? Research Sponsor Experiences Seeking Regulatory Acceptance of Digital Health Technology-Derived Endpoints [0.03%]
足够的证据有多少？寻求监管部门认可基于数字健康技术的终点的研究资助者经验
Brian Perry,Lindsay Kehoe,Teresa Swezey et al.
Brian Perry et al.
Introduction: Digital health technologies (DHTs) provide opportunities for real-time data collection and assessment of patient function. However, use of DHT-derived endpoints in clinical trials to support medical product ...
Using Clinical Scales and Digital Measures to Explore Falls in Patients with Lewy Body Dementia [0.03%]
利用临床量表和数字测量探索莱ysz体痴呆患者的跌倒问题
Chakib Battioui,Albert Man,Melissa Pugh et al.
Chakib Battioui et al.
Introduction: PRESENCE was a phase 2 clinical trial assessing the efficacy of mevidalen, a D1 receptor positive allosteric modulator, for symptomatic treatment of Lewy body dementia (LBD). Mevidalen demonstrated improveme...
Reverse Engineering of Digital Measures: Inviting Patients to the Conversation [0.03%]
数字化评价的逆向工程——邀请患者参与对话
Ieuan Clay,Nele Peerenboom,Dana E Connors et al.
Ieuan Clay et al.
Background: Digital measures offer an unparalleled opportunity to create a more holistic picture of how people who are patients behave in their real-world environments, thereby establishing a better connection between pat...
Analytical Validation of a Webcam-Based Assessment of Speech Kinematics: Digital Biomarker Evaluation following the V3 Framework [0.03%]
基于网络摄像头的语音动力学评估的分析验证：遵循V3框架的数字生物标志物评价
Leif Simmatis,Saeid Alavi Naeini,Deniz Jafari et al.
Leif Simmatis et al.
Introduction: Kinematic analyses have recently revealed a strong potential to contribute to the assessment of neurological diseases. However, the validation of home-based kinematic assessments using consumer-grade video t...
Pilot Study of a Wearable Hydration Monitor in Haemodialysis Patients: Haemodialysis Outcomes & Patient Empowerment Study 02 [0.03%]
透析患者穿戴式hydration monitor试点研究：透析结局及患者自主研究02
Vicki Sandys,Lavleen Bhat,Emer O&#x;Hare et al.
Vicki Sandys et al.
Introduction: We aimed to assess the validity and reproducibility of a wearable hydration device in a cohort of maintenance dialysis patients. Methods: ...
Feasibility of Measuring Physiological Responses to Breakthrough Infections and COVID-19 Vaccine Using a Wearable Ring Sensor [0.03%]
使用可穿戴戒指传感器测量突破性感染和COVID-19疫苗诱发的生理反应的研究可行性
Gerald Norman Pho,Nina Thigpen,Shyamal Patel et al.
Gerald Norman Pho et al.
Continuous monitoring using commercial-grade wearable technology was used to quantify the physiological response to reported COVID-19 infections and vaccinations in five biometric measurements. Larger responses were observed following confi...
Usable Data Visualization for Digital Biomarkers: An Analysis of Usability, Data Sharing, and Clinician Contact [0.03%]
数字生物标志物的可用性数据可视化：关于可用性、数据共享和临床医生联系的分析
Luke Scheuer,John Torous
Luke Scheuer
Background: While digital phenotyping smartphone apps can collect vast amounts of information on participants, less is known about how these data can be shared back. Data visualization is critical to ensuring applications...