Effects of On- and Off-Medication Periods on Walking Performance in Parkinson's Disease: Insights from Movement Synergies [0.03%]
帕金森病的服药和停药期对步行表现的影响：运动协同作用的新见解
Arunee Promsri,Peter Federolf
Arunee Promsri
Introduction: Impaired walking performance significantly impacts the quality of life in individuals with Parkinson's disease (PD). This study aimed to examine the effects of medication "on" and "off" periods on walking pe...
Feasibility of Using Smartphone Eye Tracking for Self-Recording Positional Tests [0.03%]
智能手机眼动追踪自录定位测试的可行性研究
Pouya B Bastani,Vidith Phillips,Hector Rieiro et al.
Pouya B Bastani et al.
Introduction: Benign paroxysmal positional vertigo (BPPV) is a common cause of dizziness that is diagnosed by detecting nystagmus through positional maneuvers. Limited access to expert clinicians to correctly perform and ...
Chair-Rising Power as Digital Biomarker: Validation against Jumping Power and Chair-Rising Time in Adults Aged 32-92 Years [0.03%]
椅子起身功率的数字生物标志物验证：与跳跃功率和椅子起身时间在32至92岁成人中的对比研究
Jörn Rittweger,Maik Gollasch,Roswitha Dietzel et al.
Jörn Rittweger et al.
Introduction: The chair-rising test (CRT) is being widely used to assess lower body power. The test provides valuable information about functional capacity and other health outcomes. However, most centers use timing-based...
Real-World Postural Transitions as Biomarkers of Functional Impairment in Duchenne Muscular Dystrophy [0.03%]
杜氏肌营养不良功能损害的姿势转换生物标志物研究
Cailin J Gramling,Dheeraj Dhanvee Kairamkonda,Jamie L Marshall et al.
Cailin J Gramling et al.
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder that impairs daily functioning and results in premature death. Current clinical assessments are widely used for characterizing functional impairment but have limitati...
Sidharth Abrol,Biswajit Das,Srikanth Nallanthighal et al.
Sidharth Abrol et al.
The physical basis of speech production in humans requires the coordination of multiple anatomical systems, where inhalation and exhalation of air through lungs is at the core of the phenomenon. Vocalization happens during exhalation, while...
Interpretation of Change in Novel Digital Measures: A Statistical Review and Tutorial [0.03%]
新型数字测量变化的解释：统计学回顾与教程
Andrew Trigg,Bohdana Ratitch,Frank Kruesmann et al.
Andrew Trigg et al.
Background: Novel clinical measures assessed by a digital health technology tool require thresholds to interpret change over time, such as the minimal clinically important difference. Establishing such thresholds is a key...
Analysis Method of Real-World Digital Biomarkers for Clinical Impact in Cancer Patients [0.03%]
分析癌症患者临床影响的现实世界数字生物标志物的方法
Ingrid Oakley-Girvan,Yaya Zhai,Reem Yunis et al.
Ingrid Oakley-Girvan et al.
Introduction: Wearable technologies can enhance measurements completed from home by participants in decentralized clinical trials. These measurements have shown promise in monitoring patient wellness outside the clinical ...
Analytical Validation of Wrist-Worn Accelerometer-Based Step-Count Methods during Structured and Free-Living Activities [0.03%]
用于结构化和自由生活活动的手部佩戴式加速计步数法的分析验证
Robert T Marcotte,Shelby L Bachman,Yaya Zhai et al.
Robert T Marcotte et al.
Introduction: Wrist-worn accelerometers can capture stepping behavior passively, continuously, and remotely. Methods utilizing peak detection, threshold crossing, and frequency analysis have been used to detect steps from...
Multiscale Analysis of Alzheimer's Disease Using Feature Fusion in Cognitive and Sensory Brain Regions [0.03%]
结合认知和感觉脑区特征融合的阿尔茨海默病多尺度分析方法研究
Aya Hassouneh,Alessander Danna-Dos-Santos,Bradley Bazuin et al.
Aya Hassouneh et al.
Introduction: This research is focused on early detection of Alzheimer's disease (AD) using a multiscale feature fusion framework, combining biomarkers from memory, vision, and speech regions extracted from magnetic reson...
A Holistic Approach to the Measurement of Physical Function in Clinical Research [0.03%]
临床研究中整体评价身体功能的方法
Jennifer C Richards,Shelby L Bachman,Krista Leonard-Corzo et al.
Jennifer C Richards et al.
Background: This commentary highlights the evolution of our understanding of physical function (PF) and key models/frameworks that have contributed to the current holistic understanding of PF, which encompasses not only a...