Hongyu Luo,Pierre-Alexandre Lee,Ieuan Clay et al.
Hongyu Luo et al.
Background: Fatigue is a broad, multifactorial concept encompassing feelings of reduced physical and mental energy levels. Fatigue strongly impacts patient health-related quality of life across a huge range of conditions,...
Robust Step Detection from Different Waist-Worn Sensor Positions: Implications for Clinical Studies [0.03%]
不同腰戴传感器位置下的鲁棒性步态周期检测方法及其临床意义
Matthias Tietsch,Amir Muaremi,Ieuan Clay et al.
Matthias Tietsch et al.
Analyzing human gait with inertial sensors provides valuable insights into a wide range of health impairments, including many musculoskeletal and neurological diseases. A representative and reliable assessment of gait requires continuous mo...
Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science [0.03%]
通过监管科学促进使用数字健康技术支持帕金森病药物开发的预竞争共识建设
Diane Stephenson,Robert Alexander,Varun Aggarwal et al.
Diane Stephenson et al.
Innovative tools are urgently needed to accelerate the evaluation and subsequent approval of novel treatments that may slow, halt, or reverse the relentless progression of Parkinson disease (PD). Therapies that intervene early in the diseas...
A Roadmap to Inform Development, Validation and Approval of Digital Mobility Outcomes: The Mobilise-D Approach [0.03%]
迈向数字化运动结果研发、验证及批准的路线图：Mobilise-D方法
Lynn Rochester,Claudia Mazzà,Arne Mueller et al.
Lynn Rochester et al.
Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a pressing need for tools to facilitate remote visits and monitoring. Digital health technology, including body-worn devices, offers a solution using digital...
The Path Forward for Digital Measures: Suppressing the Desire to Compare Apples and Pineapples [0.03%]
数字化度量的发展之路：抑制比较苹果与菠萝的冲动
Carrie R Houts,Bray Patrick-Lake,Ieuan Clay et al.
Carrie R Houts et al.
Digital measures are becoming more prevalent in clinical development. Methods for robust evaluation are increasingly well defined, yet the primary barrier for digital measures to transition beyond exploratory usage often relies on a compari...
Ieuan Clay
Ieuan Clay
NODE. Health Meeting Report and Panel Discussion - The FDA's Changing Regulatory Landscape for Digital Health Technologies and Digital Health Innovation during COVID-19: A Discussion with Eric Topol and Bakul Patel, Moderated by Aenor Sawyer [0.03%]
NODE健康会议报告及小组讨论——美国食品药品监督管理局(CDC)在新冠疫情下对数字医疗技术的不断变化的监管格局：埃内尔·索耶主持，埃里克·托普尔和巴库尔·帕塔尔参与讨论数字医疗创新
Anna Andoni,Shayann Ramedani,Benjamin I Rosner et al.
Anna Andoni et al.
Digital Health, Telehealth, and Primary Care Post-COVID: A Discussion with Kim Boyd and Joe Kvedar, Moderated by Benjamin Rosner [0.03%]
新冠疫情后数字化医疗、远程医疗服务与基层医疗研讨会：本杰明·罗斯纳主持金·博伊德和乔·克韦达尔参与讨论
Benjamin I Rosner,Masha Morozov,Anna Andoni
Benjamin I Rosner
Repeatability of Commonly Used Speech and Language Features for Clinical Applications [0.03%]
临床上常用的语音和语言特征的重复性研究
Gabriela M Stegmann,Shira Hahn,Julie Liss et al.
Gabriela M Stegmann et al.
Introduction: Changes in speech have the potential to provide important information on the diagnosis and progression of various neurological diseases. Many researchers have relied on open-source speech features to develop...
Evaluation of Speech-Based Digital Biomarkers: Review and Recommendations [0.03%]
基于语音的数字生物标志物评估：综述与建议
Jessica Robin,John E Harrison,Liam D Kaufman et al.
Jessica Robin et al.
Speech represents a promising novel biomarker by providing a window into brain health, as shown by its disruption in various neurological and psychiatric diseases. As with many novel digital biomarkers, however, rigorous evaluation is curre...