Parvovirus B19, Somatic Gene Mutations, and Hematologic Malignancy Subtypes: An Analytical Study [0.03%]
新型巨细胞病毒B19、体细胞性基因突变与血液系统肿瘤亚型:一项分析研究
Anfal Mohammed Khudhair,Dunya Jawad Ridha,Israa Radwan Ali et al.
Anfal Mohammed Khudhair et al.
Objective: To examine the association between somatic mutations (NPM1, FLT3, JAK2, RARA) and parvovirus B19 infection across major subtypes of myeloid malignancies, and to evaluate its potential clinical significance. ...
In Silico and In Vitro Evaluation of Novel Small Molecule Inhibitors Targeting Apoptosis Pathways in Breast Cancer Cells [0.03%]
用于靶向乳腺癌细胞凋亡途径的小分子抑制剂的体外及计算机模拟评估
Piyush Kumar,Blessing Wisdom Ike,Raman Rajesh Kumar et al.
Piyush Kumar et al.
Background: Breast cancer is one of the leading causes of cancer-related mortality globally. Recent advances in targeted therapies have focused on selectively inhibiting signalling pathways that are vital for cancer cell ...
Modification of Gold Nanoparticles Provides Antioxidant and Anti-Tumor Properties [0.03%]
改良的金纳米颗粒具有抗氧化和抗肿瘤特性
Ali G Al-Dulimi,Samah Ali Al Lateef,Mustafa Hadi et al.
Ali G Al-Dulimi et al.
Background: Metal nanoparticles such as gold (Au NPs) are less poisonous than those used in drug transporters through several features, making them predominantly suitable for biological or pharmacological requirements. ...
Real-World Effectiveness and Safety of Ribociclib Plus Aromatase Inhibitors in Patients with HR+/HER2- Metastatic Breast Cancer: A Multicenter Experience from Vietnam [0.03%]
利柏西利联合芳香化酶抑制剂治疗HR+/HER2-转移性乳腺癌的疗效和安全性:越南多中心经验
Hoa Thi Nguyen,Quang Van Le,Huyen Thi Phung et al.
Hoa Thi Nguyen et al.
Background: Although CDK4/6 inhibitors have demonstrated efficacy globally, real-world data from Vietnam are limited, primarily due to financial constraints. This study aimed to evaluate the effectiveness and toxicity of ...
Dual Repurposing Strategy: Rivaroxaban and Ciprofloxacin as a Synergistic Anticancer Therapy in Cervical Cancer: Insight into Inhibition of Metastasis via Targeting the EMT Pathway [0.03%]
双重再定位策略:利伐沙班和环丙沙星作为宫颈癌协同抗癌疗法的见解——通过靶向EMT途径抑制转移
Alyaa Aziz Ahmed
Alyaa Aziz Ahmed
Objective: This study assessed the anticancer and antimetastatic impact of rivaroxaban-ciprofloxacin mixture and explored its molecular mechanism by examining its ability to target the epithelial-mesenchymal transition (E...
MUC4 and Caspase-3 Immunoexpression in Meningioma: A Histopathological Study Linking Mucin & Apoptotic Pathways [0.03%]
脑膜瘤中MUC4和Caspase-3的免疫表达:连接黏蛋白及凋亡途径的组织病理学研究
Sara Mohamad Abou-Fandoud,Abeer Mohammed Amal Mohammed,Aya Magdy Elyamany
Sara Mohamad Abou-Fandoud
Background: The most frequent intracranial primary tumors of the central nervous system and the second most frequent tumors of the brain are meningiomas. Although most of them are benign, a subset of them is biologically ...
Prevalence of BRCA1/2 Mutation in High-Grade Non-Mucinous Ovarian Carcinoma [0.03%]
高分级非粘液性卵巢癌中BRCA1/2突变的流行率
Maria Angeline Christianto,Grace Ariani
Maria Angeline Christianto
Objective: Ovarian cancer is the third most common cancer among women with the most common subtype being high-grade ovarian carcinoma (90%), characterized by high genomic instability and somatic loss-of-function variants ...
Survival Outcomes and Mortality Predictors in Breast Cancer: An Ambidirectional Cohort Study from Central Vietnam [0.03%]
越南中部一项双向队列研究中的乳腺癌生存结局及其预后因素
Tuyen Dinh Hoang,Thang Van Vo,Chi Thi Minh Nguyen et al.
Tuyen Dinh Hoang et al.
Background: Breast cancer (BC) is one of the most common cancers worldwide; however, there is a lack of comprehensive data on survival outcomes and prognostic factors in Central Vietnam. This study aimed to estimate overa...
Thai Teachers' Knowledge, Attitude, and Awareness of E-Cigarette Use among Youth: A Sex-Based Comparative Analysis [0.03%]
泰国教师对青少年使用电子烟的知识、态度和意识:基于性别的比较分析
Jintana Sarayuthpitak,Chatchawan Tapat,Khajorn Treesopanakorn
Jintana Sarayuthpitak
Background: The rising prevalence of e-cigarette use among adolescents in Thailand poses significant public health concerns, particularly due to its association with increased risks of nicotine addiction and potential pro...
Using FMEA to Reduce the Risk of Delayed Reporting of Critical Radiological Results in Oncology: A Patient Safety Initiative [0.03%]
应用FMEA减少肿瘤科关键放射学检查结果报告延迟的风险:一项患者安全倡议
Ahmad Abu Alfwares,Bayan Qaddumi,Fadi Fawaris et al.
Ahmad Abu Alfwares et al.
Background: Timely communication of critical radiological findings is vital in oncology, where delays may jeopardize treatment and patient safety. Despite existing protocols, challenges such as manual reporting, unclear e...