A novel agent targeting APRIL: A new hope for elderly patients of IgA nephropathy [0.03%]
新型APRIL靶点制剂：为IgA肾病老年患者带来新希望
Xin Liu,Li Zuo
Xin Liu
Sibeprenlimab is a humanized IgG2 monoclonal antibody that binds to and neutralizes the activity of APRIL. It should usher in a new era in the treatment of IgAN, especially in elderly patients. ...
Diamagnetic Signature of Beta-Amyloid (Aβ) and Tau (τ) Tangle Pathology in Alzheimer's Disease: A Review [0.03%]
阿尔茨海默病中β-淀粉样蛋白(Aβ)和Tau(τ)缠结病理的反磁性特征：综述
Sadegh Ghaderi,Sana Mohammadi,Farzad Fatehi
Sadegh Ghaderi
The complex interplay between diamagnetic and paramagnetic substances within the brain, particularly in the context of Alzheimer's disease (AD), offers a rich landscape for investigation using advanced quantitative neuroimaging techniques. ...
Triglyceride-glucose index trajectories predict adverse cardiovascular outcomes in elderly heart failure patients with Diabetes: A retrospective cohort study [0.03%]
甘油三酯-葡萄糖指数轨迹预测老年心力衰竭合并糖尿病患者的不良心血管结局：一项回顾性队列研究
Hong Liu,Jian Wang,Zhi Luo et al.
Hong Liu et al.
Objective: Evaluating the change trajectories of triglyceride-glucose (TyG) index calculated after multiple tests in elderly heart failure (HF) patients may have clinical implications for predicting long-term adverse card...
Factors associated with hypercholesterolemia in older adults: A cross-sectional investigation [0.03%]
老年人高胆固醇患病因素的横断面研究
Maria Clara Alves de Oliveira,Júlia Perfeito Andrade,Ana Carolina Souza Porto et al.
Maria Clara Alves de Oliveira et al.
Objective: To investigate the factors associated with hypercholesterolemia in older adults residing in a small municipality in northeastern Brazil. Method...
SAHA inhibits lung fibroblast activation by increasing p66Shc expression epigenetically [0.03%]
SAHA通过表观遗传学增加p66Shc表达抑制肺成纤维细胞活化
Yiheng Dong,Jieting Peng,Xiangyu Zhang et al.
Yiheng Dong et al.
Objectives: To investigate the effects of suberoylanilide hydroxamic acid (SAHA) on lung fibroblast activation and to examine the role of p66Shc in this process. ...
The prevalence and outcomes of pre-admission vitamin D levels in the management of proximal femur fractures [0.03%]
术前维生素D水平在股骨近端骨折治疗中的流行病学和结局分析
Aysha Rajeev,Connor Hunter,Saurav Krishnan et al.
Aysha Rajeev et al.
Objectives: The prevalence of low Vitamin D levels (
Ultrasound blood-brain barrier opening: A new era of treatment for Alzheimer's disease? [0.03%]
聚焦超声打开血脑屏障：治疗阿尔茨海默病的新时代？
Cuiping Wang,Junhong Ren
Cuiping Wang
Predictive accuracy of comorbidity index models in assessing mortality risk among hemodialysis patients: A comprehensive single-center observational cohort study [0.03%]
评估透析患者合并症指数模型预测死亡风险的准确性的全面单中心队列研究
Yanna Yu,Fen Li,Zhan Wang et al.
Yanna Yu et al.
Objectives: Comorbidity prediction models have been demonstrated to offer more comprehensive and accurate predictions of death risk compared to single indices. However, their application in China has been limited, particu...
Trends in age-specific incidence, mortality, and DALYs of female breast cancer from 1990 to 2021 [0.03%]
1990年至2021年女性乳腺癌的年龄别新发、死亡和伤残调整寿命年变化趋势
Subhadra Priyadarshini,Kunja Bihari Panda
Subhadra Priyadarshini
Objectives: Breast cancer is a leading cause of morbidity and mortality among women worldwide. This study aims to analyze the trends in breast cancer incidence, mortality, and disability-adjusted life years (DALYs) across...
Yanwen Fang,Mengyue Yu
Yanwen Fang