Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study [0.03%]
2021年全球疾病负担研究中南亚痴呆症负担的趋势分析
Shubham Chauhan,Diptismita Jena,Shilpa Gaidhane et al.
Shubham Chauhan et al.
Objectives: This study aims to analyze the trends in the burden of Alzheimer's Disease and Other Dementias (ADoD) in South Asia from 1990 to 2021, focusing on incidence, prevalence, mortality, and Disability-Adjusted Life...
Impact of Immunosenescence on Immune-Related Adverse Events in Elderly Patients With Cancer [0.03%]
免疫衰老对癌症老年患者免疫相关不良事件的影响
Jiayi Gao,Yue Yuan,Xue Wang et al.
Jiayi Gao et al.
Immune checkpoint inhibitors (ICI), have transformed the management of several types of cancers; however, immune-related adverse events (irAEs) may cause treatment interruptions, chronic toxic effects, and death. Elderly patients are at hig...
Interaction Effect of Estimated Pulse Wave Velocity and Serum Klotho Level on Chronic Kidney Disease [0.03%]
脉波传导速度与血清Klotho水平交互作用对慢性肾病的影响
Peilin Zou,Jiajun Li,Liangkai Chen et al.
Peilin Zou et al.
Objectives: Older individuals usually have greater arterial stiffness, lower serum Klotho levels and a greater incidence of chronic kidney disease (CKD). The current study aimed to evaluate the interaction effect of estim...
Impact of a Multidisciplinary Approach to Polypharmacy Management in Community-Dwelling Older Adults: Insights From a Specialized Outpatient Clinic [0.03%]
多学科方法对社区中老年患者多重用药管理的影响：来自专科门诊的见解
Victoria Roncal-Belzunce,Marta Gutiérrez-Valencia,Bernardo Abel Cedeño-Veloz et al.
Victoria Roncal-Belzunce et al.
Objectives: The increase in polypharmacy among older adults increases the risk of drug-related problems, making multidisciplinary interventions essential. This study evaluated the impact of a multidisciplinary polypharmac...
Associations Between Gut Microbiota and Diabetic Nephropathy: A Mendelian Randomization Study [0.03%]
肠道菌群与糖尿病肾病之间的关联：一项基于孟德尔随机化的研究
Yujun Xiong,Xingyun Zhu,Huazhao Xu et al.
Yujun Xiong et al.
Objectives: Diabetic nephropathy (DN) is a severe complication of diabetes mellitus, and its pathogenesis remains incompletely understood. Emerging evidence suggests a potential link between gut microbiota and DN. This st...
Effect of Steroids on the Progression of Alzheimer's Dementia: A Retrospective Chart Review [0.03%]
类固醇对阿尔茨海默氏病程的影响：病例回顾研究
Julijana Zoran Conic,Alexandra Chetty,Lily Chen et al.
Julijana Zoran Conic et al.
Objectives: Alzheimer's disease (AD) is a prevalent age-related neurodegenerative disease that affects millions of individuals in the United States. Neuroinflammation is a driver of the neurodegenerative changes that char...
A novel agent targeting APRIL: A new hope for elderly patients of IgA nephropathy [0.03%]
新型APRIL靶点制剂：为IgA肾病老年患者带来新希望
Xin Liu,Li Zuo
Xin Liu
Sibeprenlimab is a humanized IgG2 monoclonal antibody that binds to and neutralizes the activity of APRIL. It should usher in a new era in the treatment of IgAN, especially in elderly patients. ...
Diamagnetic Signature of Beta-Amyloid (Aβ) and Tau (τ) Tangle Pathology in Alzheimer's Disease: A Review [0.03%]
阿尔茨海默病中β-淀粉样蛋白(Aβ)和Tau(τ)缠结病理的反磁性特征：综述
Sadegh Ghaderi,Sana Mohammadi,Farzad Fatehi
Sadegh Ghaderi
The complex interplay between diamagnetic and paramagnetic substances within the brain, particularly in the context of Alzheimer's disease (AD), offers a rich landscape for investigation using advanced quantitative neuroimaging techniques. ...
Triglyceride-glucose index trajectories predict adverse cardiovascular outcomes in elderly heart failure patients with Diabetes: A retrospective cohort study [0.03%]
甘油三酯-葡萄糖指数轨迹预测老年心力衰竭合并糖尿病患者的不良心血管结局：一项回顾性队列研究
Hong Liu,Jian Wang,Zhi Luo et al.
Hong Liu et al.
Objective: Evaluating the change trajectories of triglyceride-glucose (TyG) index calculated after multiple tests in elderly heart failure (HF) patients may have clinical implications for predicting long-term adverse card...
Factors associated with hypercholesterolemia in older adults: A cross-sectional investigation [0.03%]
老年人高胆固醇患病因素的横断面研究
Maria Clara Alves de Oliveira,Júlia Perfeito Andrade,Ana Carolina Souza Porto et al.
Maria Clara Alves de Oliveira et al.
Objective: To investigate the factors associated with hypercholesterolemia in older adults residing in a small municipality in northeastern Brazil. Method...