Association of small-fiber polyneuropathy with three previously unassociated rare missense SCN9A variants [0.03%]
三种罕见的SCN9A基因错义变异与小型纤维多发性神经病相关性研究
Mary A Kelley,Anne Louise Oaklander
Mary A Kelley
Background: Small fiber polyneuropathy (SFN) involves ectopic firing and degeneration of small-diameter, somatic/autonomic peripheral axons. Causes include diabetes, inflammation and rare pathogenic mutations, including i...
Anthony H Dickenson,Ryan Patel
Anthony H Dickenson
Neuropathic pain remains poorly treated, with most new drugs falling through the translational gap. The traditional model of bench-to-bedside research has relied on identifying new mechanisms/targets in animal models and then developing cli...
Evaluating the psychometric properties of the Widespread Pain Index and the Symptom Severity scale in youth with painful conditions [0.03%]
评估广泛疼痛指数和症状严重程度量表在患有疼痛状况的青少年中的心理测量属性
Joanne Dudeney,Emily F Law,Alagumeena Meyyappan et al.
Joanne Dudeney et al.
Background: Assessing features of centralized pain may prove to be clinically meaningful in pediatric populations. However, we are currently limited by the lack of validated pediatric measures. ...
Parent chronic pain and mental health symptoms impact responses to children's pain [0.03%]
父母的慢性疼痛和心理症状影响其对子女疼痛的反应
Lauren M Fussner,Cathleen Schild,Amy Lewandowski Holley et al.
Lauren M Fussner et al.
Background: Chronic pain is a prevalent health condition associated with parenting difficulties. Pain-specific parenting, such as protectiveness and catastrophizing, may contribute to chronic pain in children. Additional ...
Treatment expectations but not preference affect outcome in a trial of CBT and exercise for pain [0.03%]
疼痛的认知行为疗法和运动治疗临床试验的效果与患者的期待而非倾向有关
Marcus John Beasley,Elizabeth Alice Ferguson-Jones,Gary John Macfarlane
Marcus John Beasley
Background: Patients' beliefs and attitudes toward a treatment can affect treatment response. In unblinded trials this can affect outcomes. Aims: The aim of this analysis was to examine the association between treatment preference and expec...