Estimated Glomerular Filtration Rate Discordance and Cardiopulmonary Morbidity in Sickle Cell Disease [0.03%]
血红蛋白SC病 Discordance和心血管肺部疾病发病率的关系研究
Kabir Olaniran,Alecia Nero,Robert D Toto
Kabir Olaniran
Discordance between cystatin C- and creatinine-based estimated glomerular filtration rate (eGFR) is a recognized cardiovascular risk marker, yet its magnitude and clinical significance in sickle cell disease (SCD) remain unknown. We conduct...
Shoko Furukawa,Masahiro Takeyama,Kaoru Horiuchi et al.
Shoko Furukawa et al.
Bone Mineral Density, Bone Remodeling Biomarkers, and Hemostatic Correlates in Hemophilia and von Willebrand Disease [0.03%]
血友病和血管性假血友病患者的骨密度、骨代谢标志物及止血功能相关因素
Divyaswathi Citla-Sridhar,Simon Chung,Andrew W Brown et al.
Divyaswathi Citla-Sridhar et al.
Persons with hemophilia (PwH) have lower bone mineral density (BMD) and increased fracture risk, but data for persons with von Willebrand disease (PwVWD) are limited. Biological mechanisms underlying altered bone health in bleeding disorder...
HMA + venetoclax triplet regimens for the initial treatment of AML in adults- CONTRA [0.03%]
成人急性髓系白血病初始治疗的HMA+维奈克拉三联方案-反面观点
Maximilian Stahl,Richard M Stone
Maximilian Stahl
Etheresia Pretorius,Douglas B Kell
Etheresia Pretorius
Mutational Profiling Links Biologically Relevant Variants to Multi-Systemic Rosai-Dorfman Disease [0.03%]
突变谱分析将生物相关的变异与多系统性罗斯AI-多尔夫曼病联系起来
Gordon J Ruan,Steven Tessier,Aishwarya Ravindran et al.
Gordon J Ruan et al.
"Immunologic Dream Team": BiTEs peri-allotransplant to redirect donor lymphocytes towards GVL [0.03%]
免疫学梦之队：BiTE于移植前重定向捐赠淋巴细胞以实现GVL效应
Lorenzo Iovino,Mazyar Shadman,Filippo Milano et al.
Lorenzo Iovino et al.
Bispecific T cell engagers (BiTEs) provide high rates of responses in patients with relapsed and refractory B cell lymphomas and multiple myeloma otherwise resistant to other therapies, but unfortunately the duration of response to these tr...
Absolute Risk Trade-offs of Donor Age, Sex, and Graft Source in PTCy-Based Transplantation [0.03%]
PTCy方案移植中供者年龄、性别及移植物来源的风险收益比分析
Yosra M Aljawai,Mariam T Nawas,Shannon R McCurdy et al.
Yosra M Aljawai et al.
Atezolizumab for relapsed/refractory extranodal NK/T-cell lymphoma: the phase II NCCH1903/ATTACK trial [0.03%]
复发/难治结外自然杀伤细胞/T细胞淋巴瘤的阿特珠单抗治疗：II期NCCH1903/ATTACK试验结果
Shinichi Makita,Junji Koya,Yasuhiro Suzuki et al.
Shinichi Makita et al.
Extranodal NK/T-cell lymphoma (ENKTL) is rare and has limited treatment options available for relapsed/refractory (R/R) disease. This multicenter single-arm phase II study evaluated the efficacy and safety of atezolizumab monotherapy in pat...
Tumor-Platelet Crosstalk in Cancer: Mechanisms, Thrombotic Risk, and Translational Opportunities [0.03%]
肿瘤血小板在癌症中的相互作用：机制、促凝风险和转化机遇
Bernardo Gindri Dos Santos,Zihang Li,Tessa J Barrett
Bernardo Gindri Dos Santos
Platelets are recognized as mediators of cancer progression, extending beyond hemostasis to influence tumor growth, metastatic dissemination, immune evasion, and thrombotic complications. Tumors remodel platelets through thrombocytosis and ...