Bile Acid and Cholesterol Metabolism in Atherosclerotic Cardiovascular Disease and Therapy [0.03%]
胆酸和胆固醇代谢在动脉粥样硬化心血管疾病中的作用及其治疗意义
John Y L Chiang,Jessica M Ferrell,Yue Wu et al.
John Y L Chiang et al.
Dysregulation of lipid metabolism is a major factor contributing to atherosclerotic cardiovascular disease (ACVD), which is the number one cause of death in western countries. The liver plays a central role in maintaining whole body cholest...
Precision Medicine Considerations for the Management of Heart Disease and Stroke in East Asians [0.03%]
东亚人群精准医疗在心血管疾病和卒中管理中的考虑因素
Candida L Goodnough,Eric R Gross
Candida L Goodnough
Heart disease is the leading cause of death in Asian Americans. Importantly, people of East Asian descent are more likely to carry a loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic...